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Speech Biomarkers in Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease
May 7, 2021
… in patients with idiopathic rapid eye movement sleep behavior disorder (iRBD) and early-stage Parkinson …
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Distributed Circuit Dysfunction Underlying Motor and Sleep Deficits in a Progressive Model of Parkinson’s Disease
… it compromises the ability to move about in the world and sleep through the night . Understanding how the dysfunction … begins and then evolves to cause difficulty in moving and sleeping will allow us to diagnose PD earlier — increasing … parts of the brain, ultimately leading to both motor and sleep deficits characteristic of PD. Study Design: Our plan …
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Production of Preclinical Model of REM Sleep Behavior Disorder Using Alpha-synuclein Fibrils
… Study Rationale: REM sleep behavior disorder (RBD) is characterized by abnormal motor behaviors during the REM phase of sleep and is highly predictive of Parkinson’s disease (PD). …
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Something to Sleep On: Researchers Connect Bedtime Disorder to Higher Risk of Parkinson's Disease
March 26, 2012
… Many people with Parkinson’s disease (PD) have trouble sleeping. In addition to a general difficulty falling and then staying asleep, some deal with restless leg syndrome (an uncontrollable urge to move the legs during sleep). Others experience intense nightmares. Some …
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Assessing Parkinson’s at Home: Contactless Monitoring of Sleep, Motor Symptom Progression and Medication Response
… study investigates the feasibility of tracking mobility, sleep and quality of life in a passive, contactless manner … Parkinson’s severity, progression over time, impact on sleep and medication response without imposing any burden on … We will collect continuous readings of gait speed, sleep and other activity-related measurements passively …
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Dopamine transporter imaging predicts clinically-defined a-synucleinopathy in REM sleep behavior disorder
November 22, 2020
… Individuals with idiopathic rapid eye movement sleep behavior disorder (iRBD) are at high risk for a …