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Marianna Cortese, MD, PhD
… of neurologic diseases, such as Parkinson’s disease (PD), multiple sclerosis, and amyotrophic lateral sclerosis. She …
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Dari Shalon, PhD
… science. Returning to entrepreneurship, Dr. Shalon launched multiple Silicon Valley med-tech startups. In 2017, Dr. …
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Gastrointestinal Function in Parkinson's Mice
… and abnormal neuropathophysiology in the enteric nervous system (ENS), the semi-autonomous network of nerves that … First, alpha-synuclein accumulates in the enteric nervous system of transgenic mice in a way that is similar in … GI symptoms and their cause. Second, several of the model systems had behavioral and/or pathological abnormalities in …
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Roy Freeman, MD
… of the small nerve fibers and the autonomic nervous system. He received his MB ChB at the University of Cape … ganglionopathy, and hypoglycemia and the autonomic nervous system. Dr. Freeman is the chairman of the World Federation … of Neurology research group on the autonomic nervous system. He is the former president of the American …
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Use of HspB1 Chaperone to Inhibit Pathological Alpha-synuclein Aggregation
… disease. Here, we examine the potency of key chaperone systems and their mode of action to provide the basis for … chaperones to assess the potency of different chaperone systems in preventing alpha-synuclein aggregation. This … proteins to compare the efficiency of the studied chaperone systems. In addition, fluorescence spectroscopy can …
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Data Repository for Experimental Data
… by the Michael J Fox Foundation. We will then populate the system with data from those experiments, ensuring that our … on an existing, open-source, federally-funded database system (called 'Yogo') and will involve the creation of … engineering model of experimental design. Security of the system will be maintained at the maximum level possible to …