-
Kurt R Brunden, PhD
… Drug Discovery Foundation and an ad hoc reviewer for multiple scientific journals. Dr. Brunden has over 75 …
-
David R. Walt, PhD
… founder of Illumina and Quanterix, and he has co-founded multiple other life-sciences startups. He is a member of the …
-
Andrew Stephens, MD, PhD
… with 7,300+ citations (h-index 45) and contributed to multiple patents. …
-
Vineet Gupta, PhD
… these discoveries into clinic, Vineet has also co-founded multiple biotech startups. His current startup, Allosite …
-
Dysregulation of Ubiquitylation in Parkinson's Disease
… There is increasing evidence that the ubiquitin proteasome system has altered function in neurodegenerative diseases. … We will take advantage of our expertise in the ubiquitin system to study the functional interaction of Parkin with … there are general abnormalities in the ubiquitin proteasome system in Autosomal Recessive and other forms of Parkinson's …
-
Treating Early Cognitive Impairments and Associated Movement Control Deficits by Stimulating alpha4beta2* nAChRs
… Objective/Rationale: Cholinergic systems decline early in PD and are hypothesized to … between decline in cholinergic and dopaminergic brain systems on cognitive and motor functions; (2) to demonstrate … that the attentional deficits which result from cholinergic system decline contribute to movement control deficits; and …