… imaging scans, a tool for assessing dopamine transporter system dysfunction and thereby Parkinson’s pathology, … alpha-synuclein, such as Dementia with Lewy Bodies (DLB) or Multiple System Atrophy (MSA). The test, on its own, cannot differentiate …

… in immunological pathways, linking LRRK2 -PD to the immune system. Hypothesis: We hypothesize that LRRK2 mutations … process. Then, the “activity level” of the immune system influences disease development and progression. Study … Disease: The comparison of “activity levels” of the immune system between the above-mentioned cohorts will help us to …

… the functional role of adult neurogenesis, how the vascular system influences neurogenesis at the cellular (using a culture system) and systems level (in the rodent nervous system) in both normal …

… for Molecular Plant Physiology, working on systems biology and next-generation sequencing analysis. In … received a 5-year fellowship from the Luxembourg Centre for Systems Biomedicine (LCSB) and the Institute for Systems Biology (Hood and Dudley labs) to work on genomics …

… followed his lab elucidated the mechanisms by which this system was regulated, as well as other gene systems. Today his lab focuses on genetic and epigenetic … mechanisms of gene expression and regulation in the immune system with an emphasis on disease models. Dr. Boss has …

… will then determine when and how H1N1 infects the nervous system.  Specifically, we want to determine both the … of the infection and its sequalae in the nervous system. We will examine mice both early in the infectious … parkinsonism including cell loss, activation of the immune system within the nervous system and increases in the …