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Jeremy M. Boss, PhD
… followed his lab elucidated the mechanisms by which this system was regulated, as well as other gene systems. Today his lab focuses on genetic and epigenetic … mechanisms of gene expression and regulation in the immune system with an emphasis on disease models. Dr. Boss has …
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Influence of Immune Subtypes on the LRRK2 Phenotype
… in immunological pathways, linking LRRK2 -PD to the immune system. Hypothesis: We hypothesize that LRRK2 mutations … process. Then, the “activity level” of the immune system influences disease development and progression. Study … Disease: The comparison of “activity levels” of the immune system between the above-mentioned cohorts will help us to …
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Brandi K. Ormerod, PhD
… the functional role of adult neurogenesis, how the vascular system influences neurogenesis at the cellular (using a culture system) and systems level (in the rodent nervous system) in both normal …
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Role of H1N1 Influenza Virus in the Etiology of Parkinson's Disease
… will then determine when and how H1N1 infects the nervous system. Specifically, we want to determine both the … of the infection and its sequalae in the nervous system. We will examine mice both early in the infectious … parkinsonism including cell loss, activation of the immune system within the nervous system and increases in the …
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Stuart C. Sealfon, MD
… of Medicine and Professor of Neurobiology, Pharmacology and Systems Therapeutics. His laboratory applies diverse systems biology approaches to achieve a better understanding … signals. His research focuses on studying signaling systems, which are critical for understanding cell responses …
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Shalini Narayana, MBBS, PhD
… research emphasis is on examining the changes in the neural systems that result from neurological disorders, training, … imaging to study both normal and disordered speech motor systems. Dr. Narayana has focused on examining examined alterations in the speech motor system in patients with Parkinson’s disease, as well as its …