The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2010LRRK2 G2019S Disease Penetrance Modifiers
Objective/Rationale:
The most commonly found mutation in Parkinson’s disease patients is LRRK2 G2019S. This mutation can lead to the development of Parkinson’s disease at very different ages, from... -
MJFF Research Grant, 2010Characterization of an Inhibitor Compound of LRRK2 Function
Objective/Rationale:
LRRK2 (Leucine-Rich Repeat Kinase 2) is a protein thought to be involved in regulating signaling pathways in cells. Mutations in the gene for LRRK2 are associated with some... -
Research Grant, 2010Symptoms and Side Effects of LRRK2 Mutation Carriers and Assessment of Factors Influencing LRRK2-related PD Expression
Objective/Rationale:
By incorporating our Spanish LRRK2 cohort with G2019S and R1441G mutations into the existing LRRK2 Cohort Consortium (L2CC) of people of Ashkenazi Jewish and North African Arab... -
MJFF Research Grant, 2010Development of Selective LRRK2 Inhibitors
Objective/Rationale:
LRRK2 kinase has been implicated as a potential therapeutic target for the treatment of Parkinson’s disease. The goal of our project is to make experimental drugs to test whether... -
Rapid Response Innovation Awards, 2009Defining Genetic Factors for PD in a Conserved Population
Objective/Rationale:
The identification of genes underlying risk for Parkinson’s disease (PD) helps to further the understanding of this complex disorder, with the discovery of new genes contributing... -
Program-non-specific Funding, 2009Data Repository for Experimental Data
Objective/Rationale:
Synthesizing biomedical data into effective discoveries is greatly hampered by the way science is both reported in research articles and stored in databases. Articles do not...
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Our funding programs support basic, translational and clinical research from academia and industry.