The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2021Evaluation of a Drug that Removes Excess Iron from the Brain as a Treatment for Parkinson’s Disease
Study Rationale:
In Parkinson’s disease (PD), the death of cells in brain regions that control movement causes motor symptoms. Brain imaging studies show that iron builds up in these areas, damaging... -
Therapeutic Pipeline Program, 2021Novel Inhibitors of Cell Death for the Treatment of People with Parkinson’s Disease
Study Rationale:
Subcellular structures called mitochondria perform many critical activities for brain cells. They generate enormous amounts of energy and remove the calcium that floods into neurons... -
Therapeutic Pipeline Program, 2021Studies to Assess the Potential of Gold “Nanocrystals” for the Treatment of Parkinson’s Disease
Study Rationale:
CNM-Au8 is a new type of nanomedicine that consists of tiny crystals made of pure gold. The multifaceted surface of these gold nanocrystals provides a platform for metabolic... -
Biomarkers, 2021Measurement of Mitochondrial DNA in Early Stages of Parkinson’s Disease
Study Rationale:
People with a form of idiopathic REM sleep behavior disorder (iRBD) experience nightmares and lash out physically during a stage of sleep when the body's muscles are normally... -
Therapeutic Pipeline Program, 2021Novel Inhibitors of Protein Aggregation as Potential Therapeutics for Parkinson’s Disease
Study Rationale:
The protein alpha-synuclein can aggregate in brain cells, which leads to brain cell death in Parkinson’s disease (PD). We plan to investigate a novel class of drugs — called protein... -
Therapeutic Pipeline Program, 2021Pharmacological Targeting of Inflammation to Modify Disease Progression in Pre-clinical Models of Parkinson’s Disease
Study Rationale:
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by pronounced brain inflammation. Despite being the most common movement disorder to date, no therapy...
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Our funding programs support basic, translational and clinical research from academia and industry.