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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Integrated Analysis of Alpha-synuclein in the North American Prodromal Synucleinopathy (NAPS) Cohort

    Study Rationale: REM sleep behavior disorder is well recognized as a prodromal condition associated with a high risk of subsequently developing neurodegenerative disorders termed synucleinopathies...

  • Research Grant, 2025
    Construction of a Living Library of Digital Technologies for Use in Research and Care of Parkinson’s Disease.

    Study Rationale: Interest in digital technologies within Parkinson’s disease (sensors, devices, specific smartphone apps) for early detection and disease monitoring has increased in recent years. Over...

  • Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025
    Identifying Biochemical, Histological and Molecular Signatures of Constipation Associated with Parkinson’s Disease

    Study Rationale: Constipation is one of the most common non-motor symptoms of Parkinson’s disease (PD). It occurs in 50 to 80 percent of people with PD and doubles the risk of PD diagnosis after 10...

  • Research Grant, 2025
    Discovery of Alpha-synuclein PET Tracer for Parkinson’s Disease

    Study Rationale: In Parkinson’s disease (PD), a protein called alpha-synuclein builds up inside of brain cells. Research suggests that this protein accumulation damages the cells and eventually leads...

  • Research Grant, 2025
    Identifying Protein Changes Associated with Parkinson’s Disease: Proteomics Public Data Compilation

    Study Rationale: Accumulation of toxic protein aggregates is a hallmark of neurodegenerative disorders that include Parkinson’s disease (PD), Lewy body dementia (LBD) and multiple system atrophy (MSA)...

  • Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025
    Elucidating the Role of PINK1 and PRKN in Cell Type-specific Responses to Alpha-synuclein Pathology

    Study Rationale: Parkinson’s disease (PD) is associated with loss of dopamine neurons and aggregation of the protein alpha-synuclein. Mutations that impair the function of PINK1 and PRKN, proteins...

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