The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2013The Role of the Protein FBXO7 in Parkinsonism
Objective/Rationale:
Increasing evidence points to an important role of genetics in Parkinson’s disease (PD). Causative mutations (alterations in the DNA sequence) have been found in many... -
Therapeutic Pipeline Program, 2013Study to Evaluate RM-131 Administered to Parkinson’s Patients with Chronic Constipation
Objective/Rationale:
The purpose of this study, called MOVE-PD, is to investigate how patients with Parkinson’s disease (PD) and chronic constipation respond to the drug RM-131. The study... -
LRRK2 Target Engagement Ligand, 2013LRRK2 Target Engagement Ligand (Supplement)
Promising Outcomes of Original Grant:
New compounds from several distinct series have been synthesized that have improved inhibition of the LRRK2 enzymatic kinase activity. We assessed their... -
Research Grant, 2013Characterization of MJFF Alpha-Synuclein Filament-specific Antibodies
Objective/Rationale:
The protein alpha-synuclein aggregates abnormally in brain tissue affected by Parkinson’s disease. The present project is a follow up on a project that generated a... -
Rapid Response Innovation Awards, 2013Effect of the Stimulation Frequency of STN DBS on Swallowing Function in Patients with Parkinson’s Disease
Objective/Rationale:
The stimulation frequency in subthalamic nucleus deep brain stimulation (STN DBS) has been found to affect the axial symptoms of freezing of gait (FOG) and speech in... -
Research Grant, 2013Parkinson's Disease Biomarker Search in Cerebrospinal Fluid by Ambient Ionization Mass Spectrometry
Objective/Rationale:
This effort aims to use mass spectrometry analysis to detect and identify molecules present in a biological sample in its natural state (no dilution or extraction or other...
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Our funding programs support basic, translational and clinical research from academia and industry.