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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • RRIA (Rapid Response Innovation Awards), 2013
    Physiological Mechanism Underlying Alpha Synuclein-driven Oxidant Stress

    Objective/Rationale:            
    The formation of alpha-synuclein inclusions is the cardinal pathology of Parkinson’s disease (PD). Their appearance is accompanied by free radical (unstable atoms or...

  • RRIA (Rapid Response Innovation Awards), 2013
    Dietary Lectins and Parkinson’s Disease

    Objective/Rationale:             
    Recently it has been suggested that ingested environmental toxins may trigger a series of events, starting in the gastrointestinal tract, that eventually result in...

  • Rapid Response Innovation Awards, 2013
    Regulation of Tau Protein by MicroRNA

    Objective/Rationale:   
    We propose studies to address the overall hypothesis that small ribonucleic acids (RNAs) – molecules that code and regulate genes –contribute to the type of tau protein...

  • Research Grant, 2013
    Identification of RNAs in Carrier Protein and Exosomes Compared to RNA Found in the Whole Sample

    Objective/Rationale:          
    Isolation of RNA biomarkers from biofluids is a new promising approach to monitor health and disease. RNAs exist in different fractions of cell-free biofluids. Some are...

  • Research Grant, 2013
    Inhaled Levodopa as a Treatment for Intermittent Motor Fluctuations in Parkinson’s Disease

    Promising Outcomes of Original Grant:
    Intrapulmonary delivery of levodopa results in rapid, consistent and predictable augmentation of plasma levodopa levels in both healthy volunteers and subjects...

  • Rapid Response Innovation Awards, 2013
    Neuroprotectin D1 (NPD1) as a Disease-modifying Therapy for Parkinson’s Disease

    Objective/Rationale:             
    Progressive loss of dopaminergic neurons in Parkinson’s disease (PD) involves several pathogenic mechanisms. It may be assumed that drugs acting on more than one...

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