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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Cognition Biomarkers, 2013
    Validation of Novel and Traditional Quantitative EEG Biomarkers

    Objective/Rationale:
    Cognitive problems commonly add to the disability of the motor symptoms of Parkinson’s disease (PD), but there are no highly effective treatments for cognitive dysfunction in PD...

  • Improved Biomarkers and Clinical Outcome Measures, 2019
    Correlating MRI, Pathology and Cognitive Assessments toward Biomarkers of Cognitive Decline

    Study Rationale:
    Parkinson’s studies are working to identify magnetic resonance imaging (MRI) biomarkers for early diagnosis, disease severity and progression. However, attempts to explore how brain...

  • Defining Cognitive Phenotypes of Parkinson’s Disease, 2011
    The Relationship Between Cognitive Phenotypes of PD with Visual Hallucinations and 5HT2A Receptors in the Inferotemporal Cortex

    Objective/Rationale:
    The project aims to understand the mechanisms underlying cognitive deficits that are associated with visual hallucinations (VH) in Parkinson’s disease (PD). We have previously...

  • Cognition Biomarkers, 2013
    Validation of Computer-based Saccade Measures as a Biomarker for Neurocognitive Changes in Parkinson's Disease

    Objective/Rationale:
    Saccades are fast eye movements that shift visual focus for tasks like reading, visual searching and coordinating safe movement. Research has shown that the speed, accuracy and...

  • Research Grant, 2018
    Safety and Tolerability of GRF6021 Infusions in People with Parkinson's Disease and Cognitive Impairment

    Study Rationale & Design:
    Components of blood have been found to improve health and enhance multiple biological functions, including brain function, in older animals. Blood plasma has been...

  • Cognition Biomarkers, 2013
    Identification and Validation of Cerebrospinal Fluid Markers Related to Altered Amyloid-beta Processing in the Prediction of Dementia Associated with Parkinson’s Disease

    Objective/Rationale:             
    Patients with Parkinson’s disease (PD) are at increased risk to develop dementia compared with the general population. However, not all patients experience this...

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