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  • Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations
    2020
    Summary Details
    OPEN
    Title: Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations
    Author(s): Bramsh Q. Chandio, Shannon L. Risacher, Franco Pestilli, Daniel Bullock, Fang‐Cheng Yeh, Serge Koudoro, Ariel Rokem, Jaroslaw Harezlak, Eleftherios Garyfallidis
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-020-74054-4
    Best OA location URL: https://www.nature.com/articles/s41598-020-74054-4.pdf
    Citation Count: 104
  • Reduced striatal vesicular monoamine transporter 2 in REM sleep behavior disorder: imaging prodromal parkinsonism
    2020
    Summary Details
    OPEN
    Title: Reduced striatal vesicular monoamine transporter 2 in REM sleep behavior disorder: imaging prodromal parkinsonism
    Author(s): Leah C. Beauchamp, Victor L. Villemagne, David I. Finkelstein, Vincent Doré, Ashley I. Bush, Kevin J. Barnham, Christopher C. Rowe
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-020-74495-x
    Best OA location URL: https://www.nature.com/articles/s41598-020-74495-x.pdf
    Citation Count: 15
  • Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanisms
    2020
    Summary Details
    OPEN
    Title: Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanisms
    Author(s): Mohammad Asif Emon, Ashley Heinson, Ping Wu, Daniel Domingo‐Fernándéz, Meemansa Sood, Henri A. Vrooman, Jean‐Christophe Corvol, Phil Scordis, Martin Hofmann‐Apitius, Holger Fröhlich
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-020-76200-4
    Best OA location URL: https://publica.fraunhofer.de/handle/publica/264830
    Citation Count: 20
  • Molecular estimation of neurodegeneration pseudotime in older brains
    2020
    Summary Details
    OPEN
    Title: Molecular estimation of neurodegeneration pseudotime in older brains
    Author(s): Sumit Mukherjee, Laura Heath, Christoph Preuß, Suman Jayadev, Gwenn A. Garden, Anna K. Greenwood, Solveig K. Sieberts, Philip L. De Jager, Nilüfer Ertekin‐Taner, Gregory W. Carter, Lara M. Mangravite, Benjamin A. Logsdon
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-020-19622-y
    Best OA location URL: https://www.nature.com/articles/s41467-020-19622-y.pdf
    Citation Count: 50
  • Cerebrospinal fluid proteomics implicates the granin family in Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: Cerebrospinal fluid proteomics implicates the granin family in Parkinson’s disease
    Author(s): Melissa Rotunno, Monica Lane, Wenfei Zhang, Pavlina Wolf, Petra Oliva, Catherine Viel, Anne‐Marie Wills, Roy N. Alcalay, Clemens R. Scherzer, Lamya S. Shihabuddin, Kate Zhang, S. Pablo Sardi
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-020-59414-4
    Best OA location URL: https://www.nature.com/articles/s41598-020-59414-4.pdf
    Citation Count: 77
  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
    2020
    Summary Details
    OPEN
    Title: Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
    Author(s): Eric M. Reiman, Joseph F. Arboleda‐Velásquez, Yakeel T. Quiroz, Matthew J. Huentelman, Thomas G. Beach, Richard J. Caselli, Yinghua Chen, Yi Su, Amanda Myers, John Hardy, Jean Paul Vonsattel, Steven G. Younkin, David Bennett, Philip L. De Jager, Eric B. Larson, Paul K. Crane, C. Dirk Keene, M. Ilyas Kamboh, Julia Kofler, Linda Duque, John R. Gilbert, Harry E. Gwirtsman, Joseph D. Buxbaum, Dennis W. Dickson, Matthew P. Frosch, Bernardino Ghetti, Kathryn L. Lunetta, Li-San Wang, Bradley T. Hyman, Walter A. Kukull, Tatiana M. Foroud, Jonathan L. Haines, Richard Mayeux, Margaret A. Pericak‐Vance, Julie A. Schneider, John Q. Trojanowski, Lindsay A. Farrer, Gerard D. Schellenberg, Gary W. Beecham, Thomas J. Montine, Gyungah Jun, Erin L. Abner, Perrie M. Adams, Marilyn S. Albert, Roger L. Albin, Liana G. Apostolova, Steven E. Arnold, Sanjay Asthana, Craig Atwood, Clinton T. Baldwin, Robert C. Barber, Lisa L. Barnes, Sandra Barral, James T. Becker, Duane Beekly, Eileen H. Bigio, Thomas D. Bird, Deborah Blacker, Bradley F. Boeve, James D. Bowen, Adam Boxer, James R. Burke, Jeffrey M. Burns, Nigel J. Cairns, Laura B. Cantwell, Chuanhai Cao, Chris Carlson, Cynthia M. Carlsson, Regina M. Carney, Minerva M. Carrasquillo, Helena C. Chui, David H. Cribbs, Elizabeth Crocco, Carlos Cruchaga, Charles DeCarli, Malcolm Dick, Rachelle S. Doody, Ranjan Duara, Nilüfer Ertekin‐Taner, Denis A. Evans, Kelley Faber, Thomas Fairchild, Kenneth B. Fallon, David W. Fardo, Martin R. Farlow, Steven H. Ferris, Douglas Galasko, Marla Gearing, Daniel H. Geschwind, Valentina Ghisays, Alison Goate, Neill R. Graff‐Radford, Robert C. Green, John H. Growdon, Hákon Hákonarson, Ronald L. Hamilton, Kara L. Hamilton‐Nelson, Lindy E. Harrell, Lawrence S. Honig, Ryan M. Huebinger, Christine M. Hulette, Gail P. Jarvik, Lee‐Way Jin, Anna Karydas, Mindy J. Katz, John Kauwe, Jonathan Kaye, Ronald Kim, Neil W. Kowall, Joel H. Kramer, Brian W. Kunkle, Amanda P. Kuzma, Frank M. LaFerla, James J. Lah, Yuk Yee Leung, James B. Leverenz, Allan I. Levey, Ge Li, Andrew P. Lieberman, Richard Lipton, Oscar L. López, Constantine G. Lyketsos, John Malamon, Daniel Marson, Eden R. Martin, Frank Martiniuk, Deborah C. Mash, Eliezer Masliah, Wayne C. McCormick, Susan M. McCurry, Andrew McDavid, Stefan McDonough, Ann C. McKee, Marsel Mesulam, Bruce L. Miller, Carol A. Miller, Joshua W. Miller, John C. Morris, Shubhabrata Mukherjee, Adam C. Naj, Sid E. O’Bryant, John Olichney, Joseph E. Parisi, Henry L. Paulson, Elaine R. Peskind, Ronald Petersen, Aimee Pierce, Wayne W. Poon, Huntington Potter, Liming Qu, Joseph F. Quinn, Ashok Raj, Murray A. Raskind, ‌Barry Reisberg, Joan Reisch, Christiane Reitz, John M. Ringman, Erik D. Roberson, Ekaterina Rogaeva, Howard J. Rosen, Roger N. Rosenberg, Donald R. Royall, Mark A. Sager, Mary Sano, Andrew J. Saykin, Lon S. Schneider, William W. Seeley, Amanda Smith, Joshua A. Sonnen, Salvatore Spina, Peter St George‐Hyslop, Robert A. Stern, Russell H. Swerdlow, Rudolph E. Tanzi, Juan C. Troncoso, Debby W. Tsuang, Otto Valladares, Vivianna M. Van Deerlin, Linda J. Van Eldik, Badri N. Vardarajan, Harry V. Vinters, Sandra Weıntraub, Kathleen A. Welsh‐Bohmer, Kirk C. Wilhelmsen, Jennifer Williamson, Thomas S. Wingo, Randall L. Woltjer, Clinton B. Wright, Chuang-Kuo Wu, Chang‐En Yu, Lei Yu, Yi Zhao
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-019-14279-8
    Best OA location URL: https://escholarship.org/content/qt2n48k3rk/qt2n48k3rk.pdf
    Citation Count: 382
  • Metabolic syndrome does not influence the phenotype of LRRK2 and GBA related Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: Metabolic syndrome does not influence the phenotype of LRRK2 and GBA related Parkinson’s disease
    Author(s): Avner Thaler, Shani Shenhar‐Tsarfaty, Yanay Shaked, Tanya Gurevich, Nurit Omer, Anat Bar‐Shira, Mali Gana‐Weisz, Orly Goldstein, Meir Kestenbaum, Jesse M. Cedarbaum, Avi Orr‐Urtreger, Nir Giladi, Anat Mirelman
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-020-66319-9
    Best OA location URL: https://www.nature.com/articles/s41598-020-66319-9.pdf
    Citation Count: 21
  • Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
    2020
    Summary Details
    OPEN
    Title: Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
    Author(s): Amberley D. Stephens, Maria Zacharopoulou, Rani Moons, Giuliana Fusco, Neeleema Seetaloo, Anass Chiki, Philippa J. Woodhams, Ioanna Mela, Hilal A. Lashuel, Jonathan J. Phillips, Alfonso De Simone, Frank Sobott, Gabriele S. Kaminski Schierle
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-020-16564-3
    Best OA location URL: https://www.nature.com/articles/s41467-020-16564-3.pdf
    Citation Count: 138
  • Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
    Author(s): Julien Bryois, Nathan Skene, Thomas Hansen, Lisette J. A. Kogelman, Hunna J. Watson, Zijing Liu, Roger A.H. Adan, Lars Alfredsson, Tetsuya Ando, Ole A. Andreassen, Jessica H. Baker, Andrew W. Bergen, Wade H. Berrettini, Andreas Birgegård, Joseph M. Boden, Ilka Boehm, Claudette Boni, Vesna Boraska Perica, Harry Brandt, Gerome Breen, Julien Bryois, Katharina Buehren, Cynthia M. Bulik, Roland Burghardt, Matteo Cassina, Sven Cichon, Maurizio Clementi, Jonathan R. I. Coleman, Roger D. Cone, Philippe Courtet, Steven Crawford, Scott J. Crow, James L. Crowley, Unna N. Danner, Oliver S. P. Davis, Martina de Zwaan, George Dedoussis, Daniela Degortes, Janiece E. DeSocio, Danielle M. Dick, Dimitris Dikeos, Christian Dina, Monika Dmitrzak‐Węglarz, Elisa Docampo Martínez, Laramie E. Duncan, Karin Egberts, Stefan Ehrlich, Geòrgia Escaramís, Tõnu Esko, Xavier Estivill, Anne Farmer, Angela Favaro, Fernando Fernández‐Aranda, Manfred Fichter, Krista Fischer, Manuel Föcker, Lenka Foretová, Andreas J. Forstner, Monica Forzan, C. Franklin, Steven Gallinger, Héléna A. Gaspar, Ina Giegling, Johanna Giuranna, Paola Giusti-Rodríquez, Fragiskos Gonidakis, Scott D. Gordon, Philip Gorwood, Monica Gratacos Mayora, Jakob Grove, Sébastien Guillaume, Yiran Guo, Hákon Hákonarson, Katherine A. Halmi, Ken B. Hanscombe, Konstantinos Hatzikotoulas, Joanna Hauser, Johannes Hebebrand, Sietske G. Helder, Anjali K. Henders, Stefan Herms, Beate Herpertz‐Dahlmann, Wolfgang Herzog, Anke Hinney, L. John Horwood, Christopher Hübel, Laura M. Huckins, James I. Hudson, Hartmut Imgart, Hidetoshi Inoko, Vladimí­r Janout, Susana Jiménez‐Múrcia, Craig Johnson, Jennifer Jordan, Antonio Julià, Anders Juréus, Gursharan Kalsi, Deborah Kaminská, Allan S. Kaplan, Jaakko Kaprio, Leila Karhunen, Andreas Karwautz, Martien J. Kas, Walter H. Kaye, James L. Kennedy, Martin A. Kennedy, Anna Keski‐Rahkonen, Kirsty Kiezebrink, Youl‐Ri Kim, Katherine M. Kirk, Lars Klareskog, Kelly Klump, Gun Peggy Knudsen, Maria La Via, Mikael Landén, Janne Tidselbak Larsen, Stéphanie Le Hellard, Virpi Leppä, Robert D. Levitan, Dong Li, Paul Lichtenstein, Lisa Lilenfeld, Bochao Lin, Jolanta Lissowska, Jurjen J. Luykx, Pierre J. Magistretti, Mario Maj, Katrin Männik, Sara Marsal, Christian R. Marshall, Nicholas G. Martin, Manuel Mattheisen, Morten Mattingsdal, Sara McDevitt, Peter McGuffin, Sarah E. Medland, Andres Metspalu, Ingrid Meulenbelt, Nadia Micali, John C. Mitchell, Karen S. Mitchell, Palmiero Monteleone, Alessio Maria Monteleone, Grant W. Montgomery, Preben Bo Mortensen, Melissa A. Munn‐Chernoff, Benedetta Nacmias, Marie Navratilova, Claes Norring, Ιωάννα Ντάλλα, Catherine M. Olsen, Roel A. Ophoff, Julie O’Toole, Leonid Padyukov, Aarno Palotie, Jacques Pantel, Hana Papežová, Richard Parker, John F. Pearson, Nancy Pedersen, Liselotte Petersen, Dalila Pinto, Kirstin L. Purves, Raquel Rabionet, Anu Raevuori, Nicolás Ramoz, Ted Reichborn‐Kjennerud, Valdo Ricca, Samuli Ripatti, Stephan Ripke, Franziska Ritschel, Marion Roberts, Alessandro Rotondo, Dan Rujescu, Filip Rybakowski, Paolo Santonastaso, André Scherag, Stephen W. Scherer, Ulrike Schmidt, Nicholas J. Schork, Alexandra Schosser, Jochen Seitz, Lenka Šlachtová, P. Eline Slagboom, M Landt, Agnieszka Slopien, Sandro Sorbi, Michael Strober, Garret D. Stuber, Patrick F. Sullivan, Beata Świątkowska, Jin P. Szatkiewicz, Ioanna Tachmazidou, Elena Tenconi, Laura Thornton, Alfonso Tortorella, Federica Tozzi, Janet Treasure, Άρτεμις Τσίτσικα, Marta Tyszkiewicz‐Nwafor, Konstantinos Tziouvas, Annemarie van Elburg, Eric F. van Furth, Tracey Wade, Gudrun Wagner, Esther Walton, Hunna J. Watson, Thomas Werge, David C. Whiteman, Elisabeth Widén, D. Blake Woodside, Shuyang Yao, Zeynep Yılmaz, Eleftheria Zeggini, Stephanie Zerwas, Stephan Zipfel, Verneri Anttila, Ville Artto, Andrea Carmine Belin, Irene de Boer, Marcus Dörr, Sigrid Børte, Daniel I. Chasman, Lynn Cherkas, Anne Francke Christensen, Bru Cormand, Ester Cuenca-León, George Davey Smith, Martin Dichgans, Cornelia M. van Duijn, Tõnu Esko, Ann Louise Esserlind, Michel D. Ferrari, Rune R. Frants, Tobias Freilinger, Nick Furlotte, Padhraig Gormley, Lyn R. Griffiths, Eija Hämäläinen, Thomas Hansen, Marjo Hiekkala, M. Arfan Ikram, Andrés Ingason, Marjo‐Riitta Järvelin, Risto Kajanne, Mikko Kallela, Jaakko Kaprio, Mari Kaunisto, Lisette J. A. Kogelman, Christian Kubisch, Mitja Kurki, Tobias Kurth, Lenore Launer, Terho Lehtimäki, Davor Lessel, Lannie Ligthart, Nadia K. Litterman, Arn van den Maagdenberg, Alfons Macaya, Rainer Malik, Massimo Mangino, George McMahon, Bertram Müller‐Myhsok, Benjamin M. Neale, Carrie A. M. Northover, Dale R. Nyholt, Jes Olesen, Aarno Palotie, Priit Palta, Linda M. Pedersen, Nancy Pedersen, Daniëlle Posthuma, Patricia Pozo‐Rosich, Alice Pressman, Olli Raitakari, Markus Schürks, Cèlia Sintas, Kāri Stefánsson, Hreinn Stefánsson, Stacy Steinberg, David P. Strachan, Gisela M. Terwindt, Marta Vila‐Pueyo, Maija Wessman, Bendik S. Winsvold, Huiying Zhao, John‐Anker Zwart, Michelle Agee, Babak Alipanahi, Adam Auton, Robert K. Bell, Katarzyna Bryc, Sarah L. Elson, Pierre Fontanillas, Nicholas A. Furlotte, Karl Heilbron, David A. Hinds, Karen E. Huber, Aaron Kleinman, Nadia K. Litterman, Jennifer C. McCreight, Matthew H. McIntyre, Joanna L. Mountain, Elizabeth S. Noblin, Carrie A. M. Northover, Steven J. Pitts, J. Fah Sathirapongsasuti, Olga V. Sazonova, Janie F. Shelton, Suyash Shringarpure, Chao Tian, Joyce Y. Tung, Vladimir Vacic, Catherine H. Wilson, Leo Brueggeman, Gerome Breen, Cynthia M. Bulik, Ernest Arenas, Jens Hjerling‐Leffler, Patrick F. Sullivan
    Journal Name: Nature Genetics
    Publisher: Springer Science and Business Media LLC
    Vol: 52
    Issue #: 5
    Start Page: 482
    End Page: 493
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41588-020-0610-9
    Best OA location URL: https://kclpure.kcl.ac.uk/ws/files/151614623/Genetic_Identification_of_Cell_Types_Underlying_Brain_Complex_BREEN_Published27April2020_GREEN_AAM.pdf
    Citation Count: 295
  • Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
    2020
    Summary Details
    OPEN
    Title: Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
    Author(s): Elisabeth H. Thijssen, Renaud La Joie, Amy Wolf, Amelia Strom, Ping Wang, Leonardo Iaccarino, Viktoriya Bourakova, Yann Cobigo, Hilary W. Heuer, Salvatore Spina, Lawren VandeVrede, Xiyun Chai, Nicholas K. Proctor, David Airey, Sergey Shcherbinin, Cynthia Evans, John R. Sims, Henrik Zetterberg, Kaj Blennow, Anna M. Karydas, Charlotte E. Teunissen, Joel H. Kramer, Lea T. Grinberg, William W. Seeley, Howie Rosen, Bradley F. Boeve, Bruce L. Miller, Gil D. Rabinovici, Jeffrey L. Dage, Julio C. Rojas, Adam L. Boxer
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 26
    Issue #: 3
    Start Page: 387
    End Page: 397
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41591-020-0762-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7101073
    Citation Count: 657
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