4451 - 4475 of 6258 Results
Title
Year
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OPENTitle: A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brainJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.40202Best OA location URL: https://doi.org/10.7554/elife.40202Citation Count: 238
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OPENTitle: Importance of low diagnostic Accuracy for early Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 33Issue #: 10Start Page: 1551End Page: 1554Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.27485Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6544441Citation Count: 109
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OPENTitle: β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s diseaseJournal Name: SciencePublisher: American Association for the Advancement of Science (AAAS)Vol: 357Issue #: 6354Start Page: 891End Page: 898Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/science.aaf3934Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5761666Citation Count: 403
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OPENTitle: 14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shorteningJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 25Issue #: 1Start Page: 109End Page: 122Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddv453Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/1/109/7145789/ddv453.pdfCitation Count: 78
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OPENTitle: Illuminating G-Protein-Coupling Selectivity of GPCRsJournal Name: CellPublisher: Elsevier BVVol: 177Issue #: 7Start Page: 1933End Page: 1947.e25Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.cell.2019.04.044Best OA location URL: http://www.cell.com/article/S0092867419304969/pdfCitation Count: 549
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OPENTitle: Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with diseaseJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-018-0282-4Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-018-0282-4Citation Count: 202
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OPENTitle: Mitochondrial complex I deficiency induces Alzheimer's disease–like signatures that are reversible by targeted therapyJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 21Issue #: 8Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/alz.70519Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/12307131Citation Count: 0
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OPENTitle: Fast, multicolour optical sectioning over extended fields of view with patterned illumination and machine learningJournal Name: Biomedical Optics ExpressPublisher: Optica Publishing GroupVol: 15Issue #: 2Start Page: 1074End Page: 1074Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1364/boe.510912Best OA location URL: https://doi.org/10.1364/boe.510912Citation Count: 2
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OPENTitle: Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinaseJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 475Issue #: 1Start Page: 1End Page: 22Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bcj20170802Best OA location URL: https://portlandpress.com/biochemj/article-pdf/475/1/1/694077/bcj-2017-0802.pdfCitation Count: 145
- Pathway‐Specific Remodeling of Thalamostriatal Synapses in a Mouse Model of Parkinson's Disease2022OPENTitle: Pathway‐Specific Remodeling of Thalamostriatal Synapses in a Mouse Model of Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 6Start Page: 1164End Page: 1174Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1002/mds.29030Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29030Citation Count: 11
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OPENTitle: Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance studyJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 20Issue #: 9Start Page: 739End Page: 752Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s1474-4422(21)00214-3Best OA location URL: https://research.vumc.nl/en/publications/c35ddb07-cc7c-4ca6-ad06-b6cd811d4b63Citation Count: 424
- Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup2024OPENTitle: Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association WorkgroupJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 20Issue #: 8Start Page: 5143End Page: 5169Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/alz.13859Best OA location URL: https://hdl.handle.net/11380/1365841Citation Count: 616
- O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s disease2017OPENTitle: O-GlcNAc regulation of autophagy and α-synuclein homeostasis; implications for Parkinson’s diseaseJournal Name: Molecular BrainPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13041-017-0311-1Best OA location URL: https://molecularbrain.biomedcentral.com/track/pdf/10.1186/s13041-017-0311-1Citation Count: 81
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OPENTitle: Gender Differences in the Prevalence of Parkinson's DiseaseJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 10Issue #: 1Start Page: 86End Page: 93Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mdc3.13584Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13584Citation Count: 41
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OPENTitle: Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-023-45078-3Best OA location URL: https://www.nature.com/articles/s41598-023-45078-3.pdfCitation Count: 8
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OPENTitle: Brain structure ages—A new biomarker for multi‐disease classificationJournal Name: Human Brain MappingPublisher: WileyVol: 45Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/hbm.26558Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.26558Citation Count: 22
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OPENTitle: The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 116Issue #: 30Start Page: 14979End Page: 14988Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1073/pnas.1900289116Best OA location URL: https://escholarship.org/content/qt2wj7c9h7/qt2wj7c9h7.pdfCitation Count: 73
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OPENTitle: Efficacy of biologically-directed daylight therapy on sleep and circadian rhythm in Parkinson's disease: a randomised, double-blind, parallel-group, active-controlled, phase 2 clinical trialJournal Name: eClinicalMedicinePublisher: Elsevier BVVol: 69Issue #:Start Page: 102474End Page: 102474Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.eclinm.2024.102474Best OA location URL: http://www.thelancet.com/article/S2589537024000531/pdfCitation Count: 9
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OPENTitle: The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and humanJournal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 475Issue #: 11Start Page: 1861End Page: 1883Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bcj20180248Best OA location URL: https://portlandpress.com/biochemj/article-pdf/475/11/1861/691623/bcj-2018-0248.pdfCitation Count: 198
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OPENTitle: NeuroBooster Array: A Genome‐Wide Genotyping Platform to Study Neurological Disorders Across Diverse PopulationsJournal Name: Movement DisordersPublisher: WileyVol: 39Issue #: 11Start Page: 2039End Page: 2048Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1002/mds.29902Best OA location URL: https://doi.org/10.1002/mds.29902Citation Count: 16
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OPENTitle: Structure of the second phosphoubiquitin–binding site in parkinJournal Name: Journal of Biological ChemistryPublisher: Elsevier BVVol: 298Issue #: 7Start Page: 102114End Page: 102114Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.jbc.2022.102114Best OA location URL: http://www.jbc.org/article/S0021925822005555/pdfCitation Count: 21
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OPENTitle: Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s DiseaseJournal Name: Cell ReportsPublisher: Elsevier BVVol: 22Issue #: 4Start Page: 930End Page: 940Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.celrep.2017.12.092Best OA location URL: http://www.cell.com/article/S2211124717319290/pdfCitation Count: 456
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OPENTitle: Gastrointestinal symptoms are predictive of trajectories of cognitive functioning in de novo Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 72Issue #:Start Page: 7End Page: 12Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2020.01.009Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7179075Citation Count: 59
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OPENTitle: Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic ProfilesJournal Name: Journal of Proteome ResearchPublisher: American Chemical Society (ACS)Vol: 17Issue #: 7Start Page: 2460End Page: 2469Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/acs.jproteome.8b00224Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6599609Citation Count: 67
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OPENTitle: Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation ProgramJournal Name: NeuropathologyPublisher: WileyVol: 35Issue #: 4Start Page: 354End Page: 389Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/neup.12189Citation Count: 427