1526 - 1550 of 6324 Results
Title
Year
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OPENTitle: Discovery and characterization of a novel series of N -phenylsulfonyl-1 H -pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu 4 )Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4955388Citation Count: 5
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OPENTitle: Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's diseaseJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 13Issue #: 3Start Page: e0192497End Page: e0192497Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0192497Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0192497&type=printableCitation Count: 25
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OPENTitle: The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2Journal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 474Issue #: 9Start Page: 1547End Page: 1558Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1042/bcj20160909Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6178381Citation Count: 35
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OPENTitle: DJ-1 Interacts with and Regulates Paraoxonase-2, an Enzyme Critical for Neuronal Survival in Response to Oxidative StressJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 9Start Page: e106601End Page: e106601Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0106601Best OA location URL: https://escholarship.org/uc/item/6g52h4gcCitation Count: 46
- Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration2012OPENTitle: Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegenerationJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 122Issue #: 9Start Page: 3159End Page: 3169Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci64575Citation Count: 57
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OPENTitle: Select E2 enzymes differentially regulate parkin activation and mitophagyJournal Name: Journal of Cell SciencePublisher: The Company of BiologistsVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1242/jcs.147520Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4132391Citation Count: 69
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OPENTitle: Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep40263Best OA location URL: https://www.nature.com/articles/srep40263.pdfCitation Count: 55
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OPENTitle: LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell modelsJournal Name: Journal of Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 91Issue #: 4Start Page: 513End Page: 522Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00109-012-0984-yBest OA location URL: https://link.springer.com/content/pdf/10.1007/s00109-012-0984-y.pdfCitation Count: 74
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OPENTitle: Nonmotor Symptoms in LRRK2 G2019S Associated Parkinson’s DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 10Start Page: e108982End Page: e108982Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0108982Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0108982&type=printableCitation Count: 79
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OPENTitle: Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic MiceJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 4Start Page: e94826End Page: e94826Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0094826Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094826&type=printableCitation Count: 35
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OPENTitle: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 115Issue #: 22Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1718946115Best OA location URL: https://www.pnas.org/content/pnas/115/22/E5164.full.pdfCitation Count: 109
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OPENTitle: Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in miceJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-017-15813-8Best OA location URL: https://www.nature.com/articles/s41598-017-15813-8.pdfCitation Count: 141
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OPENTitle: Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep32583Best OA location URL: https://www.nature.com/articles/srep32583.pdfCitation Count: 22
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OPENTitle: Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neuronsJournal Name: Journal of Neuroscience ResearchPublisher: WileyVol: 89Issue #: 3Start Page: 406End Page: 417Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/jnr.22549Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6487665Citation Count: 17
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OPENTitle: APOE,MAPT, andSNCAGenes and Cognitive Performance in Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 71Issue #: 11Start Page: 1405End Page: 1405Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2014.1455Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/1900308/noi140049.pdfCitation Count: 196
- Domain-specific accuracy of the Montreal Cognitive Assessment subsections in Parkinson's disease2017OPENTitle: Domain-specific accuracy of the Montreal Cognitive Assessment subsections in Parkinson's diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 38Issue #:Start Page: 31End Page: 34Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2017.02.008Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5400012Citation Count: 59
- GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease2015OPENTitle: GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 1Start Page: 95End Page: 102Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26359Best OA location URL: http://doi.org/10.1002/mds.26359Citation Count: 189
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OPENTitle: Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and NeurodegenerationJournal Name: PLOS GeneticsPublisher: Public Library of Science (PLoS)Vol: 12Issue #: 3Start Page: e1005944End Page: e1005944Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pgen.1005944Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005944&type=printableCitation Count: 287
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OPENTitle: Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson’s disease: an observational and case–control studyJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/npjparkd.2015.2Best OA location URL: https://escholarship.org/uc/item/48r6x3tjCitation Count: 135
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OPENTitle: Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblastsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-018-19865-2Best OA location URL: https://doi.org/10.1038/s41598-018-19865-2Citation Count: 8
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OPENTitle: Parkinson disease and incidental Lewy body diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 85Issue #: 19Start Page: 1670End Page: 1679Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000002102Best OA location URL: https://n.neurology.org/content/neurology/85/19/1670.full.pdfCitation Count: 104
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OPENTitle: Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's diseaseJournal Name: Behavioural Brain ResearchPublisher: Elsevier BVVol: 230Issue #: 2Start Page: 309End Page: 316Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bbr.2011.12.007Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3324279Citation Count: 145
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OPENTitle: Activation of the unfolded protein response enhances motor recovery after spinal cord injuryJournal Name: Cell Death & DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 2Start Page: e272End Page: e272Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/cddis.2012.8Best OA location URL: https://www.nature.com/articles/cddis20128.pdfCitation Count: 137
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OPENTitle: Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian ratsJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 60Issue #: 6Start Page: 861End Page: 868Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2010.12.032Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3133531Citation Count: 71
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OPENTitle: LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complexJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2014.00049Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2014.00049/pdfCitation Count: 97