2051 - 2075 of 6509 Results
Title
Year
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OPENTitle: Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 4Start Page: 1325End Page: 1330Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0605208103Best OA location URL: http://doi.org/10.1073/pnas.0605208103Citation Count: 578
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OPENTitle: Balancing the basal ganglia circuitry: A possible new role for dopamine D2 receptors in health and diseaseJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 7Start Page: 895End Page: 903Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26282Best OA location URL: http://doi.org/10.1002/mds.26282Citation Count: 47
- Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)2010OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29
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OPENTitle: Allopregnanolone Reinstates Tyrosine Hydroxylase Immunoreactive Neurons and Motor Performance in an MPTP-Lesioned Mouse Model of Parkinson's DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 11Start Page: e50040End Page: e50040Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0050040Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0050040&type=printableCitation Count: 50
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OPENTitle: Vitamin D Status During Pregnancy and Risk of Multiple Sclerosis in Offspring of Women in the Finnish Maternity CohortJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 73Issue #: 5Start Page: 515End Page: 515Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2015.4800Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2499458/noi150103.pdfCitation Count: 169
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OPENTitle: Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu4Journal Name: ACS Combinatorial SciencePublisher: American Chemical Society (ACS)Vol: 13Issue #: 2Start Page: 159End Page: 165Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1021/co1000508Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3057427Citation Count: 8
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OPENTitle: Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)Journal Name: Cellular and Molecular Life SciencesPublisher: Springer Science and Business Media LLCVol: 69Issue #: 20Start Page: 3511End Page: 3527Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1007/s00018-012-1071-9Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00018-012-1071-9.pdfCitation Count: 33
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OPENTitle: Binding of the Radioligand SIL23 to α-Synuclein Fibrils in Parkinson Disease Brain Tissue Establishes Feasibility and Screening Approaches for Developing a Parkinson Disease Imaging AgentJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 2Start Page: e55031End Page: e55031Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0055031Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0055031&type=printableCitation Count: 116
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OPENTitle: Inhibitor treatment of peripheral mononuclear cells from Parkinson’s disease patients further validates LRRK2 dephosphorylation as a pharmacodynamic biomarkerJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep31391Best OA location URL: https://www.nature.com/articles/srep31391.pdfCitation Count: 260
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OPENTitle: Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2Journal Name: Nature Chemical BiologyPublisher: Springer Science and Business Media LLCVol: 7Issue #: 4Start Page: 203End Page: 205Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nchembio.538Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3287420Citation Count: 421
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OPENTitle: Remote control of induced dopaminergic neurons in parkinsonian ratsJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 124Issue #: 7Start Page: 3215End Page: 3229Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci74664Best OA location URL: http://www.jci.org/articles/view/74664/files/pdfCitation Count: 118
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OPENTitle: A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptorsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 1Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ncomms1085Best OA location URL: https://www.nature.com/articles/ncomms1085.pdfCitation Count: 151
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OPENTitle: LRRK2 kinase activity and biology are not uniformly predicted by its autophosphorylation and cellular phosphorylation site statusJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2014.00054Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2014.00054/pdfCitation Count: 69
- Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging2016OPENTitle: Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of AgingJournal Name: Journal of the American Geriatrics SocietyPublisher: WileyVol: 65Issue #: 4Start Page: 792End Page: 799Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/jgs.14670Best OA location URL: http://doi.org/10.1111/jgs.14670Citation Count: 56
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OPENTitle: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contextsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep29945Best OA location URL: https://www.nature.com/articles/srep29945.pdfCitation Count: 129
- Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas2011OPENTitle: Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomasJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 4Start Page: 1439End Page: 1444Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1012500108Citation Count: 88
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OPENTitle: Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathwayJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 34Issue #: 1Start Page: 95End Page: 106Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2008.12.007Best OA location URL: http://doi.org/10.1016/j.nbd.2008.12.007Citation Count: 222
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OPENTitle: The microbiome of the human lower airways: a next generation sequencing perspectiveJournal Name: World Allergy Organization JournalPublisher: Elsevier BVVol: 8Issue #:Start Page: 23End Page: 23Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1186/s40413-015-0074-zBest OA location URL: http://www.worldallergyorganizationjournal.org/article/S1939455119302200/pdfCitation Count: 43
- Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases2017OPENTitle: Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseasesJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 14Issue #: 3Start Page: 352End Page: 366Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.jalz.2017.09.012Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2017.09.012Citation Count: 140
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OPENTitle: Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 34Issue #: 8Start Page: 2077.e11End Page: 2077.e18Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.02.016Best OA location URL: http://doi.org/10.1016/j.neurobiolaging.2013.02.016Citation Count: 141
- Dysrhythmia of timed movements in Parkinson׳s disease and freezing of gait2015OPENTitle: Dysrhythmia of timed movements in Parkinson׳s disease and freezing of gaitJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1624Issue #:Start Page: 222End Page: 231Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.brainres.2015.07.041Citation Count: 27
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OPENTitle: Analysis of Mitochondrial haemoglobin in Parkinson's disease brainJournal Name: MitochondrionPublisher: Elsevier BVVol: 29Issue #:Start Page: 45End Page: 52Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.mito.2016.05.001Best OA location URL: https://doi.org/10.1016/j.mito.2016.05.001Citation Count: 26
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OPENTitle: Is the N-Back Task a Valid Neuropsychological Measure for Assessing Working Memory?Journal Name: Archives of Clinical NeuropsychologyPublisher: Oxford University Press (OUP)Vol: 24Issue #: 7Start Page: 711End Page: 717Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/arclin/acp063Best OA location URL: https://academic.oup.com/acn/article-pdf/24/7/711/11189/acp063.pdfCitation Count: 210
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OPENTitle: Light sensitization of DNA nanostructures via incorporation of photo-cleavable spacersJournal Name: Chemical CommunicationsPublisher: Royal Society of Chemistry (RSC)Vol: 51Issue #: 26Start Page: 5747End Page: 5750Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1039/c5cc00082cBest OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4394657Citation Count: 55
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OPENTitle: Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 36Issue #: 12Start Page: 3121End Page: 3129Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2015.08.017Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4838454Citation Count: 54