5851 - 5900 of 6255 Results
Title
Year
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OPENTitle: Sea cucumber-derived extract can protect skin cells from oxidative DNA damage and mitochondrial degradation, and promote wound healingJournal Name: Biomedicine & PharmacotherapyPublisher: Elsevier BVVol: 180Issue #:Start Page: 117466End Page: 117466Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.biopha.2024.117466Best OA location URL: https://doi.org/10.1016/j.biopha.2024.117466Citation Count: 0
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OPENTitle: Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylationJournal Name: Genome ResearchPublisher: Cold Spring Harbor LaboratoryVol: 33Issue #: 2Start Page: 184End Page: 196Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1101/gr.277057.122Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10069470Citation Count: 18
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OPENTitle: Analysis of PTRHD1 common and rare variants in European patients with Parkinson's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 107Issue #:Start Page: 178End Page: 180Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2021.06.005Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9662088Citation Count: 3
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OPENTitle: The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 116Issue #: 30Start Page: 14979End Page: 14988Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1073/pnas.1900289116Best OA location URL: https://escholarship.org/content/qt2wj7c9h7/qt2wj7c9h7.pdfCitation Count: 73
- Higher Risk, Higher Reward? Self‐Reported Effects of Real‐World Cannabis Use in Parkinson's Disease2022OPENTitle: Higher Risk, Higher Reward? Self‐Reported Effects of Real‐World Cannabis Use in Parkinson's DiseaseJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 9Issue #: 3Start Page: 340End Page: 350Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mdc3.13414Best OA location URL: https://doi.org/10.1002/mdc3.13414Citation Count: 18
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OPENTitle: Deep Learning and fMRI-Based Pipeline for Optimization of Deep Brain Stimulation During Parkinson’s Disease Treatment: Toward Rapid Semi-Automated Stimulation OptimizationJournal Name: IEEE Journal of Translational Engineering in Health and MedicinePublisher: Institute of Electrical and Electronics Engineers (IEEE)Vol: 12Issue #:Start Page: 589End Page: 599Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1109/jtehm.2024.3448392Best OA location URL: https://doi.org/10.1109/jtehm.2024.3448392Citation Count: 2
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OPENTitle: CSF biomarkers associated with disease heterogeneity in early Parkinson’s disease: the Parkinson’s Progression Markers Initiative studyJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 131Issue #: 6Start Page: 935End Page: 949Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-016-1552-2Best OA location URL: http://doi.org/10.1007/s00401-016-1552-2Citation Count: 199
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OPENTitle: Impaired Economy of Gait and Decreased Six-Minute Walk Distance in Parkinson's DiseaseJournal Name: Parkinson's DiseasePublisher: WileyVol: 2012Issue #:Start Page: 1End Page: 6Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2012/241754Best OA location URL: https://downloads.hindawi.com/journals/pd/2012/241754.pdfCitation Count: 36
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OPENTitle: Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factorJournal Name: Science AdvancesPublisher: American Association for the Advancement of Science (AAAS)Vol: 7Issue #: 24Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1126/sciadv.abg6677Best OA location URL: https://doi.org/10.1126/sciadv.abg6677Citation Count: 45
- Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson’s disease2024OPENTitle: Vaccination with structurally adapted fungal protein fibrils induces immunity to Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 147Issue #: 5Start Page: 1644End Page: 1652Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/brain/awae061Best OA location URL: https://doi.org/10.1093/brain/awae061Citation Count: 4
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OPENTitle: A worldwide study of subcortical shape as a marker for clinical staging in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-024-00825-9Best OA location URL: https://doi.org/10.1038/s41531-024-00825-9Citation Count: 2
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OPENTitle: UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicalsJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 454Issue #: 7206Start Page: 846End Page: 851Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nature07181Citation Count: 685
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OPENTitle: Epidemiology meets toxicogenomics: Mining toxicologic evidence in support of an untargeted analysis of pesticides exposure and Parkinson’s diseaseJournal Name: Environment InternationalPublisher: Elsevier BVVol: 170Issue #:Start Page: 107613End Page: 107613Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.envint.2022.107613Best OA location URL: https://doi.org/10.1016/j.envint.2022.107613Citation Count: 13
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OPENTitle: Self‐Report versus Clinician Examination in Early Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 3Start Page: 585End Page: 597Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.28884Best OA location URL: https://doi.org/10.1002/mds.28884Citation Count: 23
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OPENTitle: An increased rate of longitudinal cognitive decline is observed in Parkinson's disease patients with low CSF Aß42 and an APOE ε4 alleleJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 127Issue #:Start Page: 278End Page: 286Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2019.02.023Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6588475Citation Count: 26
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OPENTitle: Progression of MDS‐UPDRS Scores Over Five Years in De Novo Parkinson Disease from the Parkinson's Progression Markers Initiative CohortJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 5Issue #: 1Start Page: 47End Page: 53Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mdc3.12553Citation Count: 162
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OPENTitle: Distribution of Parkinson’s disease associated RAB39B in mouse brain tissueJournal Name: Molecular BrainPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13041-020-00584-7Best OA location URL: https://molecularbrain.biomedcentral.com/track/pdf/10.1186/s13041-020-00584-7Citation Count: 9
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OPENTitle: Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neuronsJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41531-022-00423-7Best OA location URL: https://www.nature.com/articles/s41531-022-00423-7.pdfCitation Count: 43
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OPENTitle: Cerebral chemoarchitecture shares organizational traits with brain structure and functionJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 12Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7554/elife.83843Best OA location URL: https://doi.org/10.7554/elife.83843Citation Count: 13
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OPENTitle: New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissuesJournal Name: Frontiers in Molecular BiosciencesPublisher: Frontiers Media SAVol: 10Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fmolb.2023.1087982Best OA location URL: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1087982/pdfCitation Count: 4
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OPENTitle: Posterior Cortical Cognitive Deficits Are Associated With Structural Brain Alterations in Mild Cognitive Impairment in Parkinson’s DiseaseJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 13Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2021.668559Best OA location URL: https://doi.org/10.3389/fnagi.2021.668559Citation Count: 26
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OPENTitle: Sources of PM2.5 exposure misclassification in three Finnish register-based study populations and the impact on attenuation of health effect estimatesJournal Name: Science of The Total EnvironmentPublisher: Elsevier BVVol: 954Issue #:Start Page: 176422End Page: 176422Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.scitotenv.2024.176422Best OA location URL: https://doi.org/10.1016/j.scitotenv.2024.176422Citation Count: 3
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OPENTitle: Sex effects on brain structure in de novo Parkinson’s disease: a multimodal neuroimaging studyJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 143Issue #: 10Start Page: 3052End Page: 3066Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awaa234Citation Count: 77
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OPENTitle: Development of Pyridothiophene Compounds for PET Imaging of α‐SynucleinJournal Name: Chemistry – A European JournalPublisher: WileyVol: 30Issue #: 23Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/chem.202303921Best OA location URL: https://doi.org/10.1002/chem.202303921Citation Count: 5
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OPENTitle: Comparative study of cerebrospinal fluid α‐synuclein seeding aggregation assays for diagnosis of Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 34Issue #: 4Start Page: 536End Page: 544Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.27646Best OA location URL: https://movementdisorders.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.27646Citation Count: 193
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OPENTitle: The effects of dopamine on digit span in Parkinson’s diseaseJournal Name: Journal of Clinical Movement DisordersPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40734-016-0033-zBest OA location URL: https://clinicalmovementdisorders.biomedcentral.com/track/pdf/10.1186/s40734-016-0033-zCitation Count: 23
- Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition2017OPENTitle: Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque depositionJournal Name: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseasePublisher: Elsevier BVVol: 1864Issue #: 1Start Page: 208End Page: 225Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bbadis.2017.07.005Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5875988Citation Count: 63
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OPENTitle: Deep clinical and neuropathological phenotyping of Pick diseaseJournal Name: Annals of NeurologyPublisher: WileyVol: 79Issue #: 2Start Page: 272End Page: 287Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.24559Best OA location URL: http://doi.org/10.1002/ana.24559Citation Count: 170
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OPENTitle: Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 2Start Page: 416End Page: 421Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.28846Best OA location URL: https://doi.org/10.1002/mds.28846Citation Count: 36
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OPENTitle: Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s DiseaseJournal Name: MetabolitesPublisher: MDPI AGVol: 11Issue #: 1Start Page: 29End Page: 29Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/metabo11010029Best OA location URL: https://www.mdpi.com/2218-1989/11/1/29/pdf?version=1609749889Citation Count: 106
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OPENTitle: Clinical deep brain stimulation strategies for orientation-selective pathway activationJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 15Issue #: 5Start Page: 056029End Page: 056029Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1088/1741-2552/aad978Best OA location URL: https://doi.org/10.1088/1741-2552/aad978Citation Count: 54
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OPENTitle: Validation of human microRNA target pathways enables evaluation of target prediction toolsJournal Name: Nucleic Acids ResearchPublisher: Oxford University Press (OUP)Vol: 49Issue #: 1Start Page: 127End Page: 144Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/nar/gkaa1161Best OA location URL: https://academic.oup.com/nar/article-pdf/49/1/127/35597117/gkaa1161.pdfCitation Count: 56
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OPENTitle: Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementiaJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 9Issue #: 2Start Page: 106End Page: 121Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.51482Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.51482Citation Count: 31
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OPENTitle: Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by GlucosylceramideJournal Name: NeuronPublisher: Elsevier BVVol: 97Issue #: 1Start Page: 92End Page: 107.e10Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuron.2017.12.012Best OA location URL: http://www.cell.com/article/S0896627317311352/pdfCitation Count: 195
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OPENTitle: Altered dynamics of visual contextual interactions in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-019-0085-5Best OA location URL: https://www.nature.com/articles/s41531-019-0085-5.pdfCitation Count: 8
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OPENTitle: LRRK2 Regulates Voltage-Gated Calcium Channel FunctionJournal Name: Frontiers in Molecular NeurosciencePublisher: Frontiers Media SAVol: 9Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnmol.2016.00035Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2016.00035/pdfCitation Count: 51
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OPENTitle: An alpha‐synuclein MRM assay with diagnostic potential for Parkinson's disease and monitoring disease progressionJournal Name: PROTEOMICS – Clinical ApplicationsPublisher: WileyVol: 11Issue #: 7-8Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/prca.201700045Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5540649Citation Count: 19
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OPENTitle: Novel conformation‐selective alpha‐synuclein antibodies raised against different in vitro fibril forms show distinct patterns of Lewy pathology in Parkinson's diseaseJournal Name: Neuropathology and Applied NeurobiologyPublisher: WileyVol: 43Issue #: 7Start Page: 604End Page: 620Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/nan.12402Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5632188Citation Count: 60
- LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression2024OPENTitle: LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progressionJournal Name: Translational NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1186/s40035-024-00403-2Best OA location URL: https://translationalneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s40035-024-00403-2Citation Count: 6
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OPENTitle: Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 78Issue #: 3Start Page: 312End Page: 312Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1001/jamaneurol.2020.4725Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2773698/jamaneurology_simuni_2020_oi_200091_1614894403.37383.pdfCitation Count: 111
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OPENTitle: Lewy body pathology in Alzheimer's disease: A clinicopathological prospective studyJournal Name: Acta Neurologica ScandinavicaPublisher: WileyVol: 139Issue #: 1Start Page: 76End Page: 81Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ane.13028Citation Count: 42
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OPENTitle: Detecting alpha-synuclein aggregates with small molecules on single-molecule arrayJournal Name: Chemical SciencePublisher: Royal Society of Chemistry (RSC)Vol: 16Issue #: 29Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1039/d4sc07649dBest OA location URL: https://pubs.rsc.org/en/content/articlepdf/2025/sc/d4sc07649dCitation Count: 0
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OPENTitle: The hexosamine biosynthetic pathway rescues lysosomal dysfunction in Parkinson’s disease patient iPSC derived midbrain neuronsJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-024-49256-3Best OA location URL: https://doi.org/10.1038/s41467-024-49256-3Citation Count: 7
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OPENTitle: Splicing accuracy varies across human introns, tissues, age and diseaseJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 16Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-024-55607-xBest OA location URL: https://escholarship.org/content/qt9pj488ct/qt9pj488ct.pdfCitation Count: 0
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OPENTitle: Is REM Sleep Behavior Disorder Changing? Secular Changes Versus Referral PatternsJournal Name: Movement Disorders Clinical PracticePublisher: WileyVol: 10Issue #: 10Start Page: 1519End Page: 1524Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1002/mdc3.13842Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13842Citation Count: 2
- Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson's Disease Progression2020OPENTitle: Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson's Disease ProgressionJournal Name: Movement DisordersPublisher: WileyVol: 35Issue #: 8Start Page: 1466End Page: 1471Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/mds.28073Best OA location URL: https://escholarship.org/content/qt2jx1q8tx/qt2jx1q8tx.pdfCitation Count: 27
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OPENTitle: Predicting primary progressive aphasias with support vector machine approaches in structural MRI dataJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 14Issue #:Start Page: 334End Page: 343Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2017.02.003Best OA location URL: https://doi.org/10.1016/j.nicl.2017.02.003Citation Count: 50
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OPENTitle: Severe cholinergic terminal loss in newly diagnosed dementia with Lewy bodiesJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 146Issue #: 9Start Page: 3690End Page: 3704Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awad192Best OA location URL: https://academic.oup.com/brain/article-pdf/146/9/3690/51330532/awad192.pdfCitation Count: 27
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OPENTitle: Toward Omics-Scale Quantitative Mass Spectrometry Imaging of Lipids in Brain Tissue Using a Multiclass Internal Standard MixtureJournal Name: Analytical ChemistryPublisher: American Chemical Society (ACS)Vol: 95Issue #: 51Start Page: 18719End Page: 18730Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1021/acs.analchem.3c02724Best OA location URL: https://doi.org/10.1021/acs.analchem.3c02724Citation Count: 24
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OPENTitle: BRF110, an Orally Active Nurr1-RXRα-Selective Rexinoid, Enhances BDNF Expression without Elevating TriglyceridesJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 68Issue #: 4Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1021/acs.jmedchem.4c03046Best OA location URL: https://doi.org/10.1021/acs.jmedchem.4c03046Citation Count: 4