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4131 - 4140 of 6255 Results
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  • Cortical proteins may provide motor resilience in older adults
    2021
    Summary Details
    OPEN
    Title: Cortical proteins may provide motor resilience in older adults
    Author(s): Aron S. Buchman, Lei Yu, Shahram Oveisgharan, Vladislav Petyuk, Shinya Tasaki, Chris Gaiteri, R. J. Wilson, Francine Grodstein, Julie A. Schneider, Hans‐Ulrich Klein, Philip L. De Jager, David A. Bennett
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-021-90859-3
    Best OA location URL: https://www.nature.com/articles/s41598-021-90859-3.pdf
    Citation Count: 16
  • Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration
    2021
    Summary Details
    OPEN
    Title: Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration
    Author(s): Libin Zhou, Kwangsik Nho, Maria G. Haddad, Nicole Cherepacha, Agne Tubeleviciute-Aydin, Andy P. Tsai, Andrew J. Saykin, P. Jesper Sjöström, Andréa C. LeBlanc
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-021-91367-0
    Best OA location URL: https://www.nature.com/articles/s41598-021-91367-0.pdf
    Citation Count: 12
  • A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology
    2021
    Summary Details
    OPEN
    Title: A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology
    Author(s): Jinhong Wie, Zhenjiang Liu, Haikun Song, Thomas F. Tropea, Lu Yang, Huanhuan Wang, Yuling Liang, Chunlei Cang, Kimberly Aranda, Joey Lohmann, Jing Yang, Boxun Lu, Alice Chen‐Plotkin, Kelvin C. Luk, Dejian Ren
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 591
    Issue #: 7850
    Start Page: 431
    End Page: 437
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-03185-z
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7979525
    Citation Count: 98
  • Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells
    2021
    Summary Details
    OPEN
    Title: Dysregulation of mitochondrial and proteolysosomal genes in Parkinson’s disease myeloid cells
    Author(s): Elisa Navarro, Evan Udine, Kátia de Paiva Lopes, Madison Parks, Giulietta Riboldi, Brian M. Schilder, Jack Humphrey, Gijsje J. L. Snijders, Ricardo A. Vialle, Maojuan Zhuang, Tamjeed Sikder, Charalambos Argyrou, Amanda Allan, Michael J. Chao, Kurt Farrell, Brooklyn Henderson, Sarah Simon, Deborah Raymond, Sonya Elango, Roberto A. Ortega, Vicki Shanker, Matthew Swan, Carolyn W. Zhu, Ritesh Ramdhani, Ruth H. Walker, Winona Tse, Mary Sano, Ana C. Pereira, Tim Ahfeldt, Alison Goate, Susan Bressman, John F. Crary, Lot D. de Witte, Steven J. Frucht, Rachel Saunders‐Pullman, Towfique Raj
    Journal Name: Nature Aging
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 9
    Start Page: 850
    End Page: 863
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s43587-021-00110-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8728893
    Citation Count: 35
  • Disruption of mitochondrial complex I induces progressive parkinsonism
    2021
    Summary Details
    OPEN
    Title: Disruption of mitochondrial complex I induces progressive parkinsonism
    Author(s): Patricia González‐Rodríguez, Enrico Zampese, Kristen A. Stout, Jaime N. Guzmán, Ema Ilijić, Ben Yang, Tatiana Tkatch, Mihaela Stavarache, David L. Wokosin, Lin Gao, Michael G. Kaplitt, José López‐Barneo, Paul T. Schumacker, D. James Surmeier
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 599
    Issue #: 7886
    Start Page: 650
    End Page: 656
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-04059-0
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9189968
    Citation Count: 429
  • Activation mechanism of PINK1
    2021
    Summary Details
    OPEN
    Title: Activation mechanism of PINK1
    Author(s): Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 602
    Issue #: 7896
    Start Page: 328
    End Page: 335
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-021-04340-2
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8828467
    Citation Count: 88
  • Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
    2021
    Summary Details
    OPEN
    Title: Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
    Author(s): Yiyi Ma, Eric B. Dammer, Daniel Felsky, Duc M. Duong, Hans‐Ulrich Klein, Charles C. White, Maotian Zhou, Benjamin A. Logsdon, Cristin McCabe, Jishu Xu, Minghui Wang, Thomas S. Wingo, James J. Lah, Bin Zhang, Julie A. Schneider, Mariet Allen, Xue Wang, Nilüfer Ertekin‐Taner, Nicholas T. Seyfried, Allan I. Levey, David A. Bennett, Philip L. De Jager
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-021-27204-9
    Best OA location URL: https://escholarship.org/content/qt0nc5b6ht/qt0nc5b6ht.pdf
    Citation Count: 42
  • Quantitative phosphoproteomics uncovers dysregulated kinase networks in Alzheimer’s disease
    2021
    Summary Details
    OPEN
    Title: Quantitative phosphoproteomics uncovers dysregulated kinase networks in Alzheimer’s disease
    Author(s): Nader Morshed, Meelim J. Lee, Felicia H. Rodriguez, Douglas A. Lauffenburger, Diego Mastroeni, Forest M. White
    Journal Name: Nature Aging
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 6
    Start Page: 550
    End Page: 565
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s43587-021-00071-1
    Best OA location URL:
    Citation Count: 37
  • Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
    2021
    Summary Details
    OPEN
    Title: Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
    Author(s): Angela M. Crist, Kelly M. Hinkle, Xue Wang, Christina M. Moloney, Billie J. Matchett, Sydney A. Labuzan, Isabelle Frankenhauser, Nkem O. Azu, Amanda M. Liesinger, Elizabeth R. Lesser, Daniel Serie, Zachary Quicksall, Tulsi Patel, Troy Carnwath, Michael DeTure, Xiaojia Tang, Ronald C. Petersen, Ranjan Duara, Neill R. Graff‐Radford, Mariet Allen, Minerva M. Carrasquillo, Hu Li, Owen A. Ross, Nilüfer Ertekin‐Taner, Dennis W. Dickson, Yan W. Asmann, Rickey E. Carter, Melissa E. Murray
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-021-22399-3
    Best OA location URL: https://www.nature.com/articles/s41467-021-22399-3.pdf
    Citation Count: 69
  • Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologies
    2021
    Summary Details
    OPEN
    Title: Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologies
    Author(s): Nicasia Beebe-Wang, Safiye Çelik, Ethan Weinberger, Pascal Sturmfels, Philip L. De Jager, Sara Mostafavi, Su‐In Lee
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-021-25680-7
    Best OA location URL: https://www.nature.com/articles/s41467-021-25680-7.pdf
    Citation Count: 15
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