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5681 - 5690 of 6509 Results
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  • Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples
    2020
    Summary Details
    OPEN
    Title: Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples
    Author(s): Jens O. Watzlawik, Xu Hou, Dominika Fričová, Chloe Ramnarine, Sandeep Kumar Barodia, Tania F. Gendron, Michael G. Heckman, Michael DeTure, Joanna Siuda, Zbigniew K. Wszołek, Clemens R. Scherzer, Owen A. Ross, Guojun Bu, Dennis W. Dickson, Matthew S. Goldberg, Fabienne C. Fiesel, Wolfdieter Springer
    Journal Name: Autophagy
    Publisher: Informa UK Limited
    Vol: 17
    Issue #: 9
    Start Page: 2613
    End Page: 2628
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1080/15548627.2020.1834712
    Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15548627.2020.1834712?needAccess=true
    Citation Count: 60
  • USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation
    2020
    Summary Details
    OPEN
    Title: USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation
    Author(s): Emma V. Rusilowicz-Jones, Jane Jardine, Andreas Kallinos, Adán Pinto-Fernández, Franziska Guenther, Mariacarmela Giurrandino, Francesco G. Barone, Katy R. McCarron, Christopher J. Burke, Alejandro Murad, Aitor Martinez, Elena Marcassa, Malte Gersch, Alexandre J. Buckmelter, Katherine J. Kayser-Bricker, Frédéric Lamoliatte, Akshada Gajbhiye, Simon Davis, Hannah C. Scott, Emma J. Murphy, Katherine S. England, Heather Mortiboys, David Komander, Matthias Trost, Benedikt M. Kessler, Stephanos Ioannidis, Michael K. Ahlijanian, Sylvie Urbé, Michael J. Clague
    Journal Name: Life Science Alliance
    Publisher: Life Science Alliance, LLC
    Vol: 3
    Issue #: 8
    Start Page: e202000768
    End Page: e202000768
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.26508/lsa.202000768
    Best OA location URL: https://www.life-science-alliance.org/content/lsa/3/8/e202000768.full.pdf
    Citation Count: 128
  • Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
    2020
    Summary Details
    OPEN
    Title: Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
    Author(s): Lucia Iannotta, Alice Biosa, Jillian H. Kluss, Giulia Tombesi, Alice Kaganovich, Susanna Cogo, Nicoletta Plotegher, Laura Civiero, Evy Lobbestael, Veerle Baekelandt, Mark Cookson, Elisa Greggio
    Journal Name: Cells
    Publisher: MDPI AG
    Vol: 9
    Issue #: 11
    Start Page: 2344
    End Page: 2344
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3390/cells9112344
    Best OA location URL: https://www.mdpi.com/2073-4409/9/11/2344/pdf?version=1603442755
    Citation Count: 59
  • Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations
    2020
    Summary Details
    OPEN
    Title: Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations
    Author(s): Pilar Rivero-Ríos, María Romo-Lozano, Belén Fernández, Elena Fdez, Sabine Hilfiker
    Journal Name: Cells
    Publisher: MDPI AG
    Vol: 9
    Issue #: 7
    Start Page: 1719
    End Page: 1719
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3390/cells9071719
    Best OA location URL: https://www.mdpi.com/2073-4409/9/7/1719/pdf?version=1595002890
    Citation Count: 35
  • The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia
    2020
    Summary Details
    OPEN
    Title: The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia
    Author(s): Mitchell J. Bartlett, Omar S. Mabrouk, Lajos Szabó, Andrew J. Flores, Kate L. Parent, Jean M. Bidlack, Michael L. Heien, Robert T. Kennedy, Robin Polt, Scott J. Sherman, Torsten Falk
    Journal Name: International Journal of Molecular Sciences
    Publisher: MDPI AG
    Vol: 22
    Issue #: 1
    Start Page: 20
    End Page: 20
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3390/ijms22010020
    Best OA location URL: https://www.mdpi.com/1422-0067/22/1/20/pdf?version=1608635348
    Citation Count: 10
  • Fluctuation Imaging of LRRK2 Reveals that the G2019S Mutation Alters Spatial and Membrane Dynamics
    2020
    Summary Details
    OPEN
    Title: Fluctuation Imaging of LRRK2 Reveals that the G2019S Mutation Alters Spatial and Membrane Dynamics
    Author(s): Bethany J. Sanstrum, Brandee Goo, Diana Z. Y. Holden, Donovan D. Delgado, Thien Nguyen, Kiana D. Lee, Nicholas G. James
    Journal Name: Molecules
    Publisher: MDPI AG
    Vol: 25
    Issue #: 11
    Start Page: 2561
    End Page: 2561
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3390/molecules25112561
    Best OA location URL: https://www.mdpi.com/1420-3049/25/11/2561/pdf?version=1591348343
    Citation Count: 4
  • Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
    2020
    Summary Details
    OPEN
    Title: Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
    Author(s): Ying Fan, Francesca Tonelli, Shalini Padmanabhan, Marco A. S. Baptista, Lindsey Riley, Danielle Smith, Connie Marras, Andrew J.M. Howden, Dario R. Alessi, Esther Sammler
    Journal Name: Journal of Visualized Experiments
    Publisher: MyJove Corporation
    Vol:
    Issue #: 157
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3791/58956
    Citation Count: 11
  • The Future of GDNF in Parkinson's Disease
    2020
    Summary Details
    OPEN
    Title: The Future of GDNF in Parkinson's Disease
    Author(s): Fredric P. Manfredsson, Nicole K. Polinski, Thyagarajan Subramanian, Nicholas M. Boulis, Dustin R. Wakeman, Ronald J. Mandel
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 12
    Issue #:
    Start Page: 593572
    End Page: 593572
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3389/fnagi.2020.593572
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2020.593572/pdf
    Citation Count: 49
  • Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson’s disease
    Author(s): Yaping Chu, Raymond T. Bartus, Fredric P. Manfredsson, C. Warren Olanow, Jeffrey H. Kordower
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 143
    Issue #: 3
    Start Page: 960
    End Page: 975
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/awaa020
    Best OA location URL: https://doi.org/10.1093/brain/awaa020
    Citation Count: 85
  • SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants
    2020
    Summary Details
    OPEN
    Title: SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants
    Author(s): Pavel P. Kuksa, Chien‐Yueh Lee, Alexandre Amlie‐Wolf, Prabhakaran Gangadharan, Elisabeth E. Mlynarski, Yi‐Fan Chou, Han‐Jen Lin, Heather Issen, Emily Greenfest‐Allen, Otto Valladares, Yuk Yee Leung, Li‐San Wang
    Journal Name: Bioinformatics
    Publisher: Oxford University Press (OUP)
    Vol: 36
    Issue #: 12
    Start Page: 3879
    End Page: 3881
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/bioinformatics/btaa246
    Best OA location URL: https://academic.oup.com/bioinformatics/article-pdf/36/12/3879/33437175/btaa246.pdf
    Citation Count: 14
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