6026 - 6050 of 9148 Results
Title
Year
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RESTRICTEDTitle: Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTPJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 105Issue #: 5Start Page: 1716End Page: 1721Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.0705363105Best OA location URL: http://doi.org/10.1073/pnas.0705363105Citation Count: 268
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OPENTitle: Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 109Issue #: 26Start Page: 10322End Page: 10327Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1203223109Best OA location URL: https://www.pnas.org/content/pnas/109/26/10322.full.pdfCitation Count: 99
- Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells2009OPENTitle: Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 18Start Page: 7613End Page: 7618Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0902396106Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2671325Citation Count: 231
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OPENTitle: Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 36Start Page: 15454End Page: 15459Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0813216106Best OA location URL: http://doi.org/10.1073/pnas.0813216106Citation Count: 266
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OPENTitle: Progressive dopaminergic cell loss with unilateral-to-bilateral progression in a genetic model of Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 109Issue #: 39Start Page: 15918End Page: 15923Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1205102109Best OA location URL: https://www.pnas.org/content/pnas/109/39/15918.full.pdfCitation Count: 87
- Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas2011RESTRICTEDTitle: Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomasJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 4Start Page: 1439End Page: 1444Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.1012500108Citation Count: 95
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OPENTitle: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 47Start Page: 18754End Page: 18759Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0704908104Best OA location URL: http://doi.org/10.1073/pnas.0704908104Citation Count: 435
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RESTRICTEDTitle: Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 107Issue #: 21Start Page: 9879End Page: 9884Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.1004676107Best OA location URL: http://doi.org/10.1073/pnas.1004676107Citation Count: 510
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OPENTitle: R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 34Start Page: 14622End Page: 14627Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0906334106Best OA location URL: http://doi.org/10.1073/pnas.0906334106Citation Count: 313
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 41Start Page: E3945End Page: 54Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/94836Citation Count: 213
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RESTRICTEDTitle: Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stressJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 102Issue #: 14Start Page: 5215End Page: 5220Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.0501282102Best OA location URL: http://doi.org/10.1073/pnas.0501282102Citation Count: 708
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OPENTitle: Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 27Start Page: 11441End Page: 11446Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0702717104Best OA location URL: https://www.pnas.org/doi/pdf/10.1073/pnas.0702717104Citation Count: 539
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP12014OPENTitle: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 18Start Page: 6804End Page: 6809Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321845111Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/104291Citation Count: 215
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OPENTitle: Derivation of midbrain dopamine neurons from human embryonic stem cellsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 101Issue #: 34Start Page: 12543End Page: 12548Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0404700101Best OA location URL: http://doi.org/10.1073/pnas.0404700101Citation Count: 975
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 224
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 1Start Page: E34End Page: 43Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 127
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OPENTitle: In vivo demonstration that α-synuclein oligomers are toxicJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 108Issue #: 10Start Page: 4194End Page: 4199Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1100976108Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3053976Citation Count: 1494
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OPENTitle: Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 106Issue #: 33Start Page: 14063End Page: 14068Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0900096106Best OA location URL: http://doi.org/10.1073/pnas.0900096106Citation Count: 461
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OPENTitle: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 28Start Page: 8756End Page: 8761Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1509742112Best OA location URL: https://www.pnas.org/content/pnas/112/28/8756.full.pdfCitation Count: 195
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo2015OPENTitle: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 49Start Page: E6818End Page: 24Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1519430112Best OA location URL: https://www.pnas.org/content/pnas/112/49/E6818.full.pdfCitation Count: 30
- Stochastic electrotransport selectively enhances the transport of highly electromobile molecules2015OPENTitle: Stochastic electrotransport selectively enhances the transport of highly electromobile moleculesJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 112Issue #: 46Start Page: E6274End Page: 83Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1510133112Best OA location URL: https://www.pnas.org/content/pnas/112/46/E6274.full.pdfCitation Count: 265
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OPENTitle: Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 110Issue #: 2Start Page: 636End Page: 641Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1220399110Best OA location URL: https://www.pnas.org/content/pnas/110/2/636.full.pdfCitation Count: 210
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OPENTitle: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 111Issue #: 29Start Page: 10732End Page: 10737Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321785111Best OA location URL: https://www.pnas.org/content/pnas/111/29/10732.full.pdfCitation Count: 343
- Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons2016OPENTitle: Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 113Issue #: 47Start Page: E7564End Page: E7571Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1608784113Best OA location URL: https://www.pnas.org/content/pnas/113/47/E7564.full.pdfCitation Count: 60
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OPENTitle: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasisJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 114Issue #: 5Start Page: 1165End Page: 1170Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1522872114Best OA location URL: https://www.pnas.org/content/pnas/114/5/1165.full.pdfCitation Count: 121