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  • Model-Based Comparison of Deep Brain Stimulation Array Functionality with Varying Number of Radial Electrodes and Machine Learning Feature Sets
    2016
    Summary Details
    OPEN
    Title: Model-Based Comparison of Deep Brain Stimulation Array Functionality with Varying Number of Radial Electrodes and Machine Learning Feature Sets
    Author(s): Benjamin A. Teplitzky, Laura Zitella Verbick, YiZi Xiao, Matthew D. Johnson
    Journal Name: Frontiers in Computational Neuroscience
    Publisher: Frontiers Media SA
    Vol: 10
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fncom.2016.00058
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fncom.2016.00058/pdf
    Citation Count: 41
  • Safety, tolerability, and preliminary efficacy of SYN120, a dual 5-HT6/5-HT2A antagonist, for the treatment of Parkinson disease dementia: A randomized, controlled, proof-of-concept trial
    2023
    Summary Details
    RESTRICTED
    Title: Safety, tolerability, and preliminary efficacy of SYN120, a dual 5-HT6/5-HT2A antagonist, for the treatment of Parkinson disease dementia: A randomized, controlled, proof-of-concept trial
    Author(s): Hubert H. Fernandez, Daniel Weintraub, Eric A. Macklin, Irene Litvan, Michael A. Schwarzschild, Jamie L. Eberling, Aleksandar Videnović, Christopher Kenney
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 114
    Issue #:
    Start Page: 105511
    End Page: 105511
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2023.105511
    Citation Count: 10
  • Leucine‐rich repeat kinase 2‐sensitive Na + /Ca 2+ exchanger activity in dendritic cells
    2015
    Summary Details
    RESTRICTED
    Title: Leucine‐rich repeat kinase 2‐sensitive Na + /Ca 2+ exchanger activity in dendritic cells
    Author(s): Jing Yan, Ahmad Ahnilaji, Evi Schmid, Bernat Elvira, Derya R. Shimshek, Herman van der Putten, Carsten A. Wagner, Ekaterina Shumilina, Florian Läng
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Vol: 29
    Issue #: 5
    Start Page: 1701
    End Page: 1710
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1096/fj.14-264028
    Citation Count: 19
  • A Fixable Fluorescence‐Quenched Substrate for Quantitation of Lysosomal Glucocerebrosidase Activity in Both Live and Fixed Cells
    2023
    Summary Details
    OPEN
    Title: A Fixable Fluorescence‐Quenched Substrate for Quantitation of Lysosomal Glucocerebrosidase Activity in Both Live and Fixed Cells
    Author(s): Sha Zhu, Matthew C. Deen, Yanping Zhu, Pierre‐André Gilormini, Xi Chen, Oliver B. Davis, Marcus Y. Chin, Anastasia G. Henry, David J. Vocadlo
    Journal Name: Angewandte Chemie International Edition
    Publisher: Wiley
    Vol: 62
    Issue #: 40
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/anie.202309306
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.202309306
    Citation Count: 9
  • The PINK1—Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells
    2021
    Summary Details
    OPEN
    Title: The PINK1—Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells
    Author(s): Aaron Bradshaw, Philip Campbell, Anthony H.V. Schapira, Huw R. Morris, Jan‐Willem Taanman
    Journal Name: PLOS ONE
    Publisher: Public Library of Science (PLoS)
    Vol: 16
    Issue #: 11
    Start Page: e0259903
    End Page: e0259903
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pone.0259903
    Best OA location URL: https://doi.org/10.1371/journal.pone.0259903
    Citation Count: 18
  • Increased yield of full GBA sequencing in Ashkenazi Jews with Parkinson's disease
    2018
    Summary Details
    OPEN
    Title: Increased yield of full GBA sequencing in Ashkenazi Jews with Parkinson's disease
    Author(s): Jennifer A. Ruskey, Lior Greenbaum, Léanne Roncière, Armaghan Alam, Dan Spiegelman, Christopher Liong, Oren Levy, Cheryl Waters, Stanley Fahn, Karen Marder, Wendy K. Chung, Gilad Yahalom, Simon Israeli‐Korn, Vered Livneh, Tsvia Fay‐Karmon, Roy N. Alcalay, Sharon Hassin‐Baer, Ziv Gan‐Or
    Journal Name: European Journal of Medical Genetics
    Publisher: Elsevier BV
    Vol: 62
    Issue #: 1
    Start Page: 65
    End Page: 69
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.ejmg.2018.05.005
    Citation Count: 61
  • Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
    2020
    Summary Details
    OPEN
    Title: Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
    Author(s): Ying Fan, Francesca Tonelli, Shalini Padmanabhan, Marco A. S. Baptista, Lindsey Riley, Danielle Smith, Connie Marras, Andrew J.M. Howden, Dario R. Alessi, Esther Sammler
    Journal Name: Journal of Visualized Experiments
    Publisher: MyJove Corporation
    Vol:
    Issue #: 157
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3791/58956
    Citation Count: 11
  • Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease
    2012
    Summary Details
    RESTRICTED
    Title: Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease
    Author(s): Eunju Shin, Joanna García, Christian Winkler, Anders Björklund, Manolo Carta
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 47
    Issue #: 3
    Start Page: 393
    End Page: 406
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2012.03.038
    Best OA location URL: https://doaj.org/article/1e207e4e620e4951aa04424fd03c5cff
    Citation Count: 41
  • Cross‐validation of optimized composites for preclinical Alzheimer's disease
    2016
    Summary Details
    OPEN
    Title: Cross‐validation of optimized composites for preclinical Alzheimer's disease
    Author(s): Michael Donohue, Chung‐Kai Sun, Rema Raman, Philip S. Insel, Paul Aisen
    Journal Name: Alzheimer's & Dementia: Translational Research & Clinical Interventions
    Publisher: Wiley
    Vol: 3
    Issue #: 1
    Start Page: 123
    End Page: 129
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.trci.2016.12.001
    Best OA location URL: https://doi.org/10.1016/j.trci.2016.12.001
    Citation Count: 23
  • Latency of subthalamic nucleus deep brain stimulation-evoked cortical activity as a potential biomarker for postoperative motor side effects
    2020
    Summary Details
    OPEN
    Title: Latency of subthalamic nucleus deep brain stimulation-evoked cortical activity as a potential biomarker for postoperative motor side effects
    Author(s): Zachary T. Irwin, Mohammad Z. Awad, Christopher L. Gonzalez, Arie Nakhmani, J. Nicole Bentley, Thomas A. Moore, Kenneth G. Smithson, Barton L. Guthrie, Harrison C. Walker
    Journal Name: Clinical Neurophysiology
    Publisher: Elsevier BV
    Vol: 131
    Issue #: 6
    Start Page: 1221
    End Page: 1229
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.clinph.2020.02.021
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7214089
    Citation Count: 15
  • What Parkinson's disease patients say in their own words about their mood and anxiety symptoms
    2024
    Summary Details
    RESTRICTED
    Title: What Parkinson's disease patients say in their own words about their mood and anxiety symptoms
    Author(s): Karen E. Anderson, Connie Marras, Amy W. Amara, Lana M. Chahine, Shirley Eberly, Abhishek Hosamath, Daniel Kinel, Sneha Mantri, Soania Mathur, David Oakes, Jennifer L. Purks, David G. Standaert, Daniel Weintraub, Ira Shoulson, Lakshmi Arbatti
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 130
    Issue #:
    Start Page: 107190
    End Page: 107190
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2024.107190
    Citation Count: 0
  • Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury
    2014
    Summary Details
    OPEN
    Title: Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury
    Author(s): Nigel H. Greig, David Tweedie, Lital Rachmany, Yazhou Li, Vardit Rubovitch, Shaul Schreiber, Yung‐Hsiao Chiang, Barry J. Hoffer, Jonathan P. Miller, Debomoy K. Lahiri, Kumar Sambamurti, Robert E. Becker, Chaim G. Pick
    Journal Name: Alzheimer's & Dementia
    Publisher: Wiley
    Vol: 10
    Issue #: 1S
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jalz.2013.12.011
    Best OA location URL: http://doi.org/10.1016/j.jalz.2013.12.011
    Citation Count: 69
  • Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
    2018
    Summary Details
    OPEN
    Title: Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
    Author(s): Alban Ordureau, João A. Paulo, Wei Zhang, Tim Ahfeldt, Jiuchun Zhang, Erin F. Cohn, Zhonggang Hou, Jin‐Mi Heo, Lee L. Rubin, Sachdev S. Sidhu, Steven P. Gygi, J. Wade Harper
    Journal Name: Molecular Cell
    Publisher: Elsevier BV
    Vol: 70
    Issue #: 2
    Start Page: 211
    End Page: 227.e8
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.molcel.2018.03.012
    Best OA location URL: http://www.cell.com/article/S1097276518302156/pdf
    Citation Count: 179
  • Grey matter abnormalities are associated only with severe cognitive decline in early stages of Parkinson's disease
    2019
    Summary Details
    OPEN
    Title: Grey matter abnormalities are associated only with severe cognitive decline in early stages of Parkinson's disease
    Author(s): Amée F. Wolters, Anja J.H. Moonen, Renaud Lopes, Albert F.G. Leentjens, Annelien Duits, Luc Defebvre, Christine Delmaire, Paul A.M. Hofman, Frank C. van Bussel, Kathy Dujardin
    Journal Name: Cortex
    Publisher: Elsevier BV
    Vol: 123
    Issue #:
    Start Page: 1
    End Page: 11
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.cortex.2019.09.015
    Best OA location URL: https://cris.maastrichtuniversity.nl/en/publications/226efa6a-7701-420c-935c-2c284c758e52
    Citation Count: 16
  • What’s the target: understanding two decades of in silico microRNA-target prediction
    2019
    Summary Details
    RESTRICTED
    Title: What’s the target: understanding two decades of in silico microRNA-target prediction
    Author(s): Fabian Kern, Christina Backes, Pascal Hirsch, Tobias Fehlmann, Martin Hart, Eckart Meese, Andreas Keller, Fabian Kern, Christina Backes, Pascal Hirsch, Tobias Fehlmann, Martin Hart, Eckart Meese, Andreas Keller
    Journal Name: Briefings in Bioinformatics
    Publisher: Oxford University Press (OUP)
    Vol: 21
    Issue #: 6
    Start Page: 1999
    End Page: 2010
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1093/bib/bbz111
    Citation Count: 51
  • Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia
    2022
    Summary Details
    OPEN
    Title: Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia
    Author(s): Rebecca L. Miller, Dhruva D. Dhavale, Jennifer Y. O’Shea, Kristin M. Andruska, Jialu Liu, Erin Franklin, Chandana Buddhala, Susan K. Loftin, John R. Cirrito, Richard J. Perrin, Nigel J. Cairns, Meghan C. Campbell, Joel S. Perlmutter, Paul T. Kotzbauer
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 9
    Issue #: 2
    Start Page: 106
    End Page: 121
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.51482
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.51482
    Citation Count: 35
  • Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease
    2018
    Summary Details
    OPEN
    Title: Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease
    Author(s): Measho Abreha, Eric B. Dammer, Lingyan Ping, Tian Zhang, Duc M. Duong, Marla Gearing, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: PROTEOMICS
    Publisher: Wiley
    Vol: 18
    Issue #: 20
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/pmic.201800108
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6283072
    Citation Count: 66
  • Oxidative Damage in Parkinson's Disease
    2005
    Summary Details
    RESTRICTED
    Title: Oxidative Damage in Parkinson's Disease
    Author(s): Todd Sherer, J. Timothy Greenamyre
    Journal Name: Antioxidants & Redox Signaling
    Publisher: Mary Ann Liebert Inc
    Vol: 7
    Issue #: 5-6
    Start Page: 627
    End Page: 629
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1089/ars.2005.7.627
    Citation Count: 27
  • Topiramate as an adjunct to amantadine in the treatment of dyskinesia in parkinson's disease: A randomized, double‐blind, placebo‐controlled multicenter study
    2017
    Summary Details
    RESTRICTED
    Title: Topiramate as an adjunct to amantadine in the treatment of dyskinesia in parkinson's disease: A randomized, double‐blind, placebo‐controlled multicenter study
    Author(s): Christopher G. Goetz, Glenn T. Stebbins, Kathryn A. Chung, Anthony P. Nicholas, Robert A. Hauser, Douglas Merkitch, Mark Stacy
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 32
    Issue #: 9
    Start Page: 1335
    End Page: 1336
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27092
    Citation Count: 13
  • Characterization of AN6001, a positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors
    2019
    Summary Details
    RESTRICTED
    Title: Characterization of AN6001, a positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors
    Author(s): Marloes van Hout, Jessica L. Klein, Philip K. Ahring, David T. Brown, Siganya Thaneshwaran, Altair Brito dos Santos, Anders A. Jensen, Kristi A. Kohlmeier, Palle Christophersen, Tino Dyhring
    Journal Name: Biochemical Pharmacology
    Publisher: Elsevier BV
    Vol: 174
    Issue #:
    Start Page: 113788
    End Page: 113788
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.bcp.2019.113788
    Citation Count: 5
  • Utilising functional MRI (fMRI) to explore the freezing phenomenon in Parkinson’s disease
    2011
    Summary Details
    RESTRICTED
    Title: Utilising functional MRI (fMRI) to explore the freezing phenomenon in Parkinson’s disease
    Author(s): James M. Shine, Philip B. Ward, Sharon L. Naismith, Mark Pearson, Simon J.G. Lewis
    Journal Name: Journal of Clinical Neuroscience
    Publisher: Elsevier BV
    Vol: 18
    Issue #: 6
    Start Page: 807
    End Page: 810
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.jocn.2011.02.003
    Citation Count: 36
  • Jumping to overcome freezing of gait while turning in Parkinson's disease
    2019
    Summary Details
    RESTRICTED
    Title: Jumping to overcome freezing of gait while turning in Parkinson's disease
    Author(s): Karlo J. Lizárraga, Bhairavei Gnanamanogaran, Alfonso Fasano, Anthony E. Lang
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 64
    Issue #:
    Start Page: 349
    End Page: 351
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2019.04.021
    Citation Count: 2
  • A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults
    2025
    Summary Details
    OPEN
    Title: A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults
    Author(s): Jordan L. Schultz, Phillip E. Gander, Craig D. Workman, Laura L. Boles Ponto, Stephen Cross, Christopher Nance, Christopher L. Groth, Eric B. Taylor, Sarah E. Ernst, Jia Xu, Manuchair Ebadi, Vincent A. Magnotta, Michael J. Welsh, Nandakumar S. Narayanan
    Journal Name: Journal of Parkinson’s Disease
    Publisher: SAGE Publications
    Vol: 15
    Issue #: 7
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc, cc-by-nc
    DOI - Digital Object Identifier: 10.1177/1877718x251356503
    Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/1877718X251356503
    Citation Count: 0
  • Sex differences in LRRK2 G2019S and idiopathic Parkinson's Disease
    2017
    Summary Details
    OPEN
    Title: Sex differences in LRRK2 G2019S and idiopathic Parkinson's Disease
    Author(s): Marta San Luciano, Cuiling Wang, Roberto A. Ortega, Nir Giladi, Karen Marder, Susan Bressman, Rachel Saunders‐Pullman
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 4
    Issue #: 11
    Start Page: 801
    End Page: 810
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.489
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.489
    Citation Count: 35
  • Inflammatory profile in LRRK2-associated prodromal and clinical PD
    2016
    Summary Details
    OPEN
    Title: Inflammatory profile in LRRK2-associated prodromal and clinical PD
    Author(s): Kathrin Brockmann, Anja Apel, Claudia Schulte, Nicole Schneiderhan‐Marra, Claustre Pont‐Sunyer, Dolores Vilas, Javier Ruiz‐Martínez, Markus Langkamp, Jean‐Christophe Corvol, Florence Cormier, Thomas Knorpp, Thomas Joos, Thomas Gasser, Birgitt Schüle, Jan Aasly, Tatiana Foroud, J.F. Martí-Massó, Alexis Brice, Eduardo Tolosa, Connie Marras, Daniela Berg, Walter Maetzler
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-016-0588-5
    Best OA location URL: https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-016-0588-5
    Citation Count: 66
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