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  • A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
    2010
    Summary Details
    OPEN
    Title: A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions
    Author(s): Sheila M. Fleming, Caitlin Mulligan, Franziska Richter, Farzad Mortazavi, Vincent Lemesre, Carmen Frías, Chunni Zhu, Alistair Stewart, Illana Gozes, Bruce H. Morimoto, Marie‐Françoise Chesselet
    Journal Name: Molecular and Cellular Neuroscience
    Publisher: Elsevier BV
    Vol: 46
    Issue #: 3
    Start Page: 597
    End Page: 606
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.mcn.2010.12.011
    Best OA location URL: https://europepmc.org/articles/pmc3046337?pdf=render
    Citation Count: 71
  • Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
    2010
    Summary Details
    OPEN
    Title: Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
    Author(s): Rahul Srinivasan, Rigo Pantoja, Fraser J. Moss, Elisha D.W. Mackey, Çağdaş Devrim Son, Julie M. Miwa, Henry A. Lester
    Journal Name: Journal of General Physiology
    Publisher: Rockefeller University Press
    Vol: 137
    Issue #: 1
    Start Page: 59
    End Page: 79
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1085/jgp.201010532
    Best OA location URL: https://rupress.org/jgp/article-pdf/137/1/59/1187438/jgp_201010532.pdf
    Citation Count: 162
  • TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
    2010
    Summary Details
    OPEN
    Title: TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
    Author(s): NiCole A. Finch, Minerva M. Carrasquillo, Matthew Baker, Nicola J. Rutherford, Giovanni Coppola, Mariely DeJesus‐Hernandez, Richard Crook, T. Hunter, Roberta Ghidoni, Luisa Benussi, Julia E. Crook, Elizabeth Finger, K.J. Hantanpaa, Anna M. Karydas, Pheth Sengdy, John Gonzalez, William W. Seeley, Nancy Johnson, Thomas G. Beach, Marsel Mesulam, Gianluigi Forloni, Andrew Kertesz, David S. Knopman, Ryan J. Uitti, Charles L. White, Richard J. Caselli, Carol F. Lippa, Eileen H. Bigio, Zbigniew K. Wszołek, Giuliano Binetti, Ian R. Mackenzie, Bruce L. Miller, Bradley F. Boeve, Steven G. Younkin, Dennis W. Dickson, Ronald C. Petersen, Neill R. Graff‐Radford, Daniel H. Geschwind, Rosa Rademakers
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 5
    Start Page: 467
    End Page: 474
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31820a0e3b
    Best OA location URL: https://n.neurology.org/content/neurology/76/5/467.full.pdf
    Citation Count: 233
  • Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
    2010
    Summary Details
    OPEN
    Title: Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
    Author(s): Beate Winner, H.L. Melrose, Chen Zhao, K.M. Hinkle, Mei Yue, Caroline Kent, Adam Braithwaite, Sina Ogholikhan, Robert Aigner, Jürgen Winkler, Matthew J. Farrer, F H Gage
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 41
    Issue #: 3
    Start Page: 706
    End Page: 716
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.12.008
    Best OA location URL:
    Citation Count: 184
  • Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
    2010
    Summary Details
    RESTRICTED
    Title: Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
    Author(s): Rebecca Banerjee, M. Flint Beal, Bobby Thomas
    Journal Name: Trends in Neurosciences
    Publisher: Elsevier BV
    Vol: 33
    Issue #: 12
    Start Page: 541
    End Page: 549
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.tins.2010.09.001
    Best OA location URL: https://europepmc.org/articles/pmc2981680?pdf=render
    Citation Count: 190
  • Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics
    2010
    Summary Details
    RESTRICTED
    Title: Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics
    Author(s): Suneil K. Kalia, Lorraine V. Kalia, Pamela J. McLean
    Journal Name: CNS & Neurological Disorders - Drug Targets
    Publisher: Bentham Science Publishers Ltd.
    Vol: 9
    Issue #: 6
    Start Page: 741
    End Page: 753
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2174/187152710793237386
    Best OA location URL: https://europepmc.org/articles/pmc3364514?pdf=render
    Citation Count: 93
  • N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouse
    2010
    Summary Details
    OPEN
    Title: N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouse
    Author(s): Ari Berman, Wai‐Yee Chan, Angela Brennan, Reno C. Reyes, Brittany Adler, Sang Won Suh, Tiina M. Kauppinen, Ylva Edling, Raymond A. Swanson
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 69
    Issue #: 3
    Start Page: 509
    End Page: 520
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.22162
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22162
    Citation Count: 130
  • Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains
    2010
    Summary Details
    OPEN
    Title: Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains
    Author(s): Raymond T. Bartus, Christopher D. Herzog, Yaping Chu, Alistair Wilson, Lamar Brown, João Siffert, Eugene M. Johnson, C. Warren Olanow, Elliott J. Mufson, Jeffrey H. Kordower
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 1
    Start Page: 27
    End Page: 36
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23442
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6333467
    Citation Count: 164
  • HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease
    2010
    Summary Details
    OPEN
    Title: HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease
    Author(s): C. Savio Chan, Kelly E. Glajch, Tracy S. Gertler, Jaime N. Guzmán, Jeff Mercer, Alan S. Lewis, Alan B Goldberg, Tatiana Tkatch, Ryuichi Shigemoto, Sheila M. Fleming, Dane M. Chetkovich, Pavel Osten, Hitoshi Kita, D. James Surmeier
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 1
    Start Page: 85
    End Page: 92
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2692
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3058391
    Citation Count: 183
  • Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: Time course of protection and neurorestoration
    2010
    Summary Details
    OPEN
    Title: Effects of intrastriatal GDNF on the response of dopamine neurons to 6-hydroxydopamine: Time course of protection and neurorestoration
    Author(s): Ann D. Cohen, Michael J. Zigmond, Amanda Smith
    Journal Name: Brain Research
    Publisher: Elsevier BV
    Vol: 1370
    Issue #:
    Start Page: 80
    End Page: 88
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.brainres.2010.11.006
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3019295
    Citation Count: 41
  • SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
    2010
    Summary Details
    OPEN
    Title: SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
    Author(s): Ignácio F. Mata, Min Shi, Pinky Agarwal, Kathryn A. Chung, Karen L. Edwards, Stewart A. Factor, Douglas Galasko, Carmen Ginghină, Alida Griffith, Donald S. Higgins, Denise M. Kay, Hojoong Kim, James B. Leverenz, Joseph F. Quinn, John W. Roberts, Ali Samii, Katherine W. Snapinn, Debby W. Tsuang, Dora Yearout, Jing Zhang, Haydeh Payami, Cyrus P. Zabetian
    Journal Name: Archives of Neurology
    Publisher: American Medical Association (AMA)
    Vol: 67
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/archneurol.2010.279
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3010848
    Citation Count: 166
  • Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
    2010
    Summary Details
    OPEN
    Title: Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression
    Author(s): Min Shi, Joshua M. Bradner, Aneeka M. Hancock, Kathryn A. Chung, Joseph F. Quinn, Elaine R. Peskind, Douglas Galasko, Joseph Jankovic, Cyrus P. Zabetian, Hojoong M. Kim, James B. Leverenz, Thomas J. Montine, Carmen Ginghină, Un Jung Kang, Kevin C. Cain, Yu Wang, Jan Aasly, David Goldstein, Jing Zhang
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 69
    Issue #: 3
    Start Page: 570
    End Page: 580
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.22311
    Best OA location URL:
    Citation Count: 405
  • Chaperone-mediated autophagy: machinery, regulation and biological consequences
    2010
    Summary Details
    RESTRICTED
    Title: Chaperone-mediated autophagy: machinery, regulation and biological consequences
    Author(s): Wenming Li, Qian Yang, Zixu Mao
    Journal Name: Cellular and Molecular Life Sciences
    Publisher: Springer Science and Business Media LLC
    Vol: 68
    Issue #: 5
    Start Page: 749
    End Page: 763
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00018-010-0565-6
    Best OA location URL:
    Citation Count: 111
  • Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease
    2010
    Summary Details
    OPEN
    Title: Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease
    Author(s): Kenya Nishioka, Carles Vilariño‐Güell, Stephanie A. Cobb, Jennifer M. Kachergus, Owen A. Ross, Emna Hentati, Fayçal Hentati, Matthew J. Farrer
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 16
    Issue #: 10
    Start Page: 686
    End Page: 687
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2010.09.007
    Best OA location URL: http://doi.org/10.1016/j.parkreldis.2010.09.007
    Citation Count: 40
  • CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
    2010
    Summary Details
    OPEN
    Title: CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
    Author(s): Rudy J. Castellani, Summer L. Nugent, Alan L. Morrison, Xiongwei Zhu, Hyoung‐gon Lee, Peggy L.R. Harris, Vladan Bajić, Hari Shanker Sharma, Shu G. Chen, Peter Oettgen, George Perry, Mark A. Smith
    Journal Name: Journal of Neural Transmission
    Publisher: Springer Science and Business Media LLC
    Vol: 118
    Issue #: 1
    Start Page: 23
    End Page: 26
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00702-010-0485-5
    Best OA location URL: https://europepmc.org/articles/pmc3090073?pdf=render
    Citation Count: 13
  • Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    2010
    Summary Details
    OPEN
    Title: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    Author(s): Moussa B. H. Youdim
    Journal Name: Rambam Maimonides Medical Journal
    Publisher: Rambam Health Corporation
    Vol: 1
    Issue #: 2
    Start Page: e0011
    End Page: e0011
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.5041/rmmj.10011
    Best OA location URL: https://www.rmmj.org.il/userimages/13/0/PublishFiles/13Article.pdf
    Citation Count: 8
  • PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
    2010
    Summary Details
    RESTRICTED
    Title: PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
    Author(s): Bin Zheng, Zhixiang Liao, Joseph J. Locascio, Kristen A. Lesniak, Sarah S. Roderick, Marla L. Watt, Aron C. Eklund, Yanli Zhang‐James, Peter D. Kim, Michael A. Hauser, Edna Grünblatt, Linda Moran, Silvia Mandel, Peter Riederer, Renee M. Miller, Howard J. Federoff, Ullrich Wüllner, Spyridon Papapetropoulos, Moussa B. H. Youdim, Ippolita Cantuti‐Castelvetri, Anne B. Young, Jeffery M. Vance, Richard L. Davis, John C. Hedreen, Charles H. Adler, Thomas G. Beach, Manuel B. Graeber, Frank A. Middleton, Jean‐Christophe Rochet, Clemens R. Scherzer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 2
    Issue #: 52
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.3001059
    Best OA location URL: https://europepmc.org/articles/pmc3129986?pdf=render
    Citation Count: 709
  • A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
    2010
    Summary Details
    OPEN
    Title: A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
    Author(s): Praseeda Mullasseril, Kasper B. Hansen, Katie M. Vance, Kevin K. Ogden, Hongjie Yuan, Natalie L. Kurtkaya, Rose Santangelo, Anna G. Orr, Phuong T. Le, Kimberly Vellano, Dennis C. Liotta, Stephen F. Traynelis
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/ncomms1085
    Best OA location URL: https://www.nature.com/articles/ncomms1085.pdf
    Citation Count: 151
  • Biomarkers in Parkinson‘s Disease: A Funder‘s Perspective
    2010
    Summary Details
    RESTRICTED
    Title: Biomarkers in Parkinson‘s Disease: A Funder‘s Perspective
    Author(s): Mark Frasier, Sohini Chowdhury, Jamie L. Eberling, Todd Sherer
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 5
    Start Page: 723
    End Page: 729
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.89
    Best OA location URL:
    Citation Count: 17
  • Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    2010
    Summary Details
    RESTRICTED
    Title: Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    Author(s): Ruth Roberts, Robert A. Smith, Stephen Safe, Csaba Szabó, Ronald B. Tjalkens, Fredika M. Robertson
    Journal Name: Toxicology
    Publisher: Elsevier BV
    Vol: 276
    Issue #: 2
    Start Page: 85
    End Page: 94
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.tox.2010.07.009
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237863
    Citation Count: 181
  • Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis
    2010
    Summary Details
    RESTRICTED
    Title: Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis
    Author(s): Sara Cipriani, Xiqun Chen, Michael A. Schwarzschild
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 5
    Start Page: 701
    End Page: 712
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.94
    Best OA location URL: https://europepmc.org/articles/pmc3049925?pdf=render
    Citation Count: 119
  • Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
    2010
    Summary Details
    OPEN
    Title: Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
    Author(s): S. A. Factor, N. Kyle Steenland, Donald S. Higgins, Eric Molho, Denise M. Kay, Jennifer S. Montimurro, A. R. Rosen, Cyrus P. Zabetian, Haydeh Payami
    Journal Name: Journal of Neurology, Neurosurgery & Psychiatry
    Publisher: BMJ
    Vol: 82
    Issue #: 5
    Start Page: 564
    End Page: 568
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1136/jnnp.2010.222042
    Best OA location URL: http://doi.org/10.1136/jnnp.2010.222042
    Citation Count: 100
  • Estimation of Particulate Mass and Manganese Exposure Levels among Welders
    2010
    Summary Details
    RESTRICTED
    Title: Estimation of Particulate Mass and Manganese Exposure Levels among Welders
    Author(s): Angela Hobson, Noah Seixas, David A. Sterling, Brad A. Racette
    Journal Name: The Annals of Occupational Hygiene
    Publisher: Oxford University Press (OUP)
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1093/annhyg/meq069
    Best OA location URL: https://academic.oup.com/annweh/article-pdf/55/1/113/11209915/meq069.pdf
    Citation Count: 44
  • Qualitative Imaging of Adeno-Associated Virus Serotype 2–Human Aromatic L-Amino Acid Decarboxylase Gene Therapy in a Phase I Study for the Treatment of Parkinson Disease
    2010
    Summary Details
    RESTRICTED
    Title: Qualitative Imaging of Adeno-Associated Virus Serotype 2–Human Aromatic L-Amino Acid Decarboxylase Gene Therapy in a Phase I Study for the Treatment of Parkinson Disease
    Author(s): Francisco Valles, Massimo S. Fiandaca, Jamie L. Eberling, Philip A. Starr, Paul Larson, Chadwick W. Christine, John Forsayeth, R. Mark Richardson, Lei Su, Michael J. Aminoff, Krystof S. Bankiewicz
    Journal Name: Neurosurgery
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 67
    Issue #: 5
    Start Page: 1377
    End Page: 1385
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1227/neu.0b013e3181f53a5c
    Best OA location URL:
    Citation Count: 67
  • A comparative study of Lrrk2 function in primary neuronal cultures
    2010
    Summary Details
    OPEN
    Title: A comparative study of Lrrk2 function in primary neuronal cultures
    Author(s): Justus C. Dächsel, Bahareh Behrouz, Mei Yue, Joel E. Beevers, Heather L. Melrose, Matthew J. Farrer
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 16
    Issue #: 10
    Start Page: 650
    End Page: 655
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2010.08.018
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3159957
    Citation Count: 81
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