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  • Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
    2024
    Summary Details
    OPEN
    Title: Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
    Author(s): Ana Florencia Vega-Benedetti, Clara Porcedda, Tommaso Ercoli, Giuliana Fusco, Chiara Burgaletto, Rita Pillai, Francesca Palmas, Anna Cantone, Fabrizio Angius, Paolo Solla, Alfonso De Simone, Giuseppina Cantarella, Cesarina Giallongo, Valeria Sogos, Giovanni Defazio, Anna R. Carta
    Journal Name: Journal of Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 271
    Issue #: 9
    Start Page: 5916
    End Page: 5929
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00415-024-12554-3
    Best OA location URL: https://doi.org/10.1007/s00415-024-12554-3
    Citation Count: 0
  • Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation
    2019
    Summary Details
    OPEN
    Title: Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation
    Author(s): Ying‐Qiu Zheng, Yu Zhang, Yvonne Yau, Yashar Zeighami, Kevin Larcher, Bratislav Miŝić, Alain Dagher
    Journal Name: PLOS Biology
    Publisher: Public Library of Science (PLoS)
    Vol: 17
    Issue #: 11
    Start Page: e3000495
    End Page: e3000495
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1371/journal.pbio.3000495
    Best OA location URL: https://doi.org/10.1371/journal.pbio.3000495
    Citation Count: 124
  • LRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesias
    2016
    Summary Details
    OPEN
    Title: LRRK2 phosphorylation level correlates with abnormal motor behaviour in an experimental model of levodopa-induced dyskinesias
    Author(s): Jennifer Stanic, Manuela Mellone, Maria Daniela Cirnaru, María Dolores Pérez‐Carrión, Elisa Zianni, Mónica Di Luca, Fabrizio Gardoni, Giovanni Piccoli
    Journal Name: Molecular Brain
    Publisher: Springer Science and Business Media LLC
    Vol: 9
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13041-016-0234-2
    Best OA location URL: https://molecularbrain.biomedcentral.com/track/pdf/10.1186/s13041-016-0234-2
    Citation Count: 13
  • Generalization of deep learning models for ultra-low-count amyloid PET/MRI using transfer learning
    2020
    Summary Details
    OPEN
    Title: Generalization of deep learning models for ultra-low-count amyloid PET/MRI using transfer learning
    Author(s): Kevin T. Chen, M Schürer, Jiahong Ouyang, Mary Ellen I. Koran, Guido Davidzon, Elizabeth C. Mormino, Solveig Tiepolt, Karl‐Titus Hoffmann, Osama Sabri, Greg Zaharchuk, Henryk Barthel
    Journal Name: European Journal of Nuclear Medicine and Molecular Imaging
    Publisher: Springer Science and Business Media LLC
    Vol: 47
    Issue #: 13
    Start Page: 2998
    End Page: 3007
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00259-020-04897-6
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7680289
    Citation Count: 42
  • OFF episode quality of life impact scale (OFFELIA): A new measure of quality of life for off episodes in Parkinson's disease
    2024
    Summary Details
    OPEN
    Title: OFF episode quality of life impact scale (OFFELIA): A new measure of quality of life for off episodes in Parkinson's disease
    Author(s): Maja Kuharić, Victoria Kulbokas, Kent A. Hanson, Jonathan Nazari, Kanya Shah, Ai Thi Thuy Nguyen, Tara R. Hensle, Connie Marras, Melissa J. Armstrong, Yash J. Jalundhwala, A. Simon Pickard
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 123
    Issue #:
    Start Page: 106070
    End Page: 106070
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2024.106070
    Best OA location URL: http://www.prd-journal.com/article/S1353802024000828/pdf
    Citation Count: 1
  • Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
    2017
    Summary Details
    OPEN
    Title: Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
    Author(s): Marcel Scheepstra, Sebastian A. Andrei, R.M.J.M. de Vries, Femke A. Meijer, Jian‐Nong Ma, Ethan S. Burstein, Roger Olsson, Christian Ottmann, L.‐G. Milroy, Luc Brunsveld
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 8
    Issue #: 9
    Start Page: 2065
    End Page: 2077
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1021/acschemneuro.7b00216
    Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00216
    Citation Count: 23
  • Genome‐Wide Analysis of Structural Variants in Parkinson Disease
    2023
    Summary Details
    OPEN
    Title: Genome‐Wide Analysis of Structural Variants in Parkinson Disease
    Author(s): Kimberley J. Billingsley, Jinhui Ding, Pilar Álvarez Jerez, Anastasia Illarionova, Kristin Levine, Francis P. Grenn, Mary B. Makarious, Anni Moore, Dan Vitale, Xylena Reed, Dena Hernández, Ali Torkamani, Mina Ryten, John Hardy, Ruth Chia, Sonja W. Scholz, Bryan J. Traynor, Clifton L. Dalgard, Debra Ehrlich, Toshiko Tanaka, Luigi Ferrucci, Thomas G. Beach, Geidy E. Serrano, John P. Quinn, Vivien J. Bubb, Ryan L. Collins, Xuefang Zhao, Mark Walker, Emma Pierce‐Hoffman, Harrison Brand, Michael E. Talkowski, Bradford Casey, Mark Cookson, Androo J. Markham, Mike A. Nalls, Medhat Mahmoud, Fritz J. Sedlazeck, Cornelis Blauwendraat, J. Raphael Gibbs, Andrew Singleton
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 93
    Issue #: 5
    Start Page: 1012
    End Page: 1022
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/ana.26608
    Best OA location URL: https://pub.dzne.de/record/255487
    Citation Count: 26
  • Advantages of timing the duration of a freezing of gait-provoking test in individuals with Parkinson’s disease
    2020
    Summary Details
    RESTRICTED
    Title: Advantages of timing the duration of a freezing of gait-provoking test in individuals with Parkinson’s disease
    Author(s): Talia Herman, Moria Dagan, Shirley Shema-Shiratzky, Tal Reches, Marina Brozgol, Nir Giladi, Brad Manor, Jeffrey M. Hausdorff
    Journal Name: Journal of Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 267
    Issue #: 9
    Start Page: 2582
    End Page: 2588
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00415-020-09856-7
    Citation Count: 9
  • Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha‐Synuclein Disease
    2024
    Summary Details
    OPEN
    Title: Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha‐Synuclein Disease
    Author(s): Ethan Brown, Lana M. Chahine, Andrew Siderowf, Caroline Gochanour, Ryan Kurth, Micah J. Marshall, Chelsea Caspell‐Garcia, Michael C. Brumm, Craig Stanley, Monica Korell, Bridget McMahon, Maggie Kuhl, Kimberly Fabrizio, Laura Heathers, Luis Concha‐Marambio, Claudio Soto, Sohini Chowdhury, Christopher S. Coffey, Tatiana M. Foroud, Tanya Simuni, Kenneth Marek, Caroline M. Tanner
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 97
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/ana.27158
    Best OA location URL: https://escholarship.org/uc/item/5vs9p83m
    Citation Count: 4
  • Lack of evidence for association of UQCRC1 with Parkinson's disease in Europeans
    2020
    Summary Details
    OPEN
    Title: Lack of evidence for association of UQCRC1 with Parkinson's disease in Europeans
    Author(s): Konstantin Senkevich, Sara Bandrés‐Ciga, Ziv Gan‐Or, Lynne Krohn
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 101
    Issue #:
    Start Page: 297.e1
    End Page: 297.e4
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2020.10.030
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8938960
    Citation Count: 9
  • Hoehn and Yahr stage 3 and postural stability item in the movement disorder society–unified Parkinson's disease rating scale
    2018
    Summary Details
    RESTRICTED
    Title: Hoehn and Yahr stage 3 and postural stability item in the movement disorder society–unified Parkinson's disease rating scale
    Author(s): Deepak Gupta, Stanley Fahn, Curtis Tatsuoka, Un Jung Kang
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 7
    Start Page: 1188
    End Page: 1189
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27453
    Citation Count: 4
  • Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
    2020
    Summary Details
    OPEN
    Title: Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
    Author(s): Mathieu Bourdenx, Aurélien Nioche, Sandra Doveró, Marie-Laure Arotçarena, Sandrine Camus, Grégory Porras, Marie-Laure Thiolat, Nicolas P. Rougier, Alice Prigent, P. Aubert, Sylvain Bohic, Christophe Sandt, Florent Laferrière, Évelyne Doudnikoff, Niels Kruse, Brit Mollenhauer, Salvatore Novello, Michele Morari, Thierry Leste‐Lasserre, Inés Trigo‐Damas, Michel Goillandeau, Céline Perier, Cristina Estrada, Nuria García‐Carrillo, Ariadna Recasens, Nishant N. Vaikath, Omar M. A. El‐Agnaf, María Trinidad Herrero, Pascal Derkinderen, Miquel Vila, José Á. Obeso, Benjamin Dehay, Erwan Bézard
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 6
    Issue #: 20
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.aaz9165
    Best OA location URL: http://hdl.handle.net/11392/2420388
    Citation Count: 53
  • echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline
    2021
    Summary Details
    OPEN
    Title: echolocatoR: an automated end-to-end statistical and functional genomic fine-mapping pipeline
    Author(s): Brian M. Schilder, Jack Humphrey, Towfique Raj
    Journal Name: Bioinformatics
    Publisher: Oxford University Press (OUP)
    Vol: 38
    Issue #: 2
    Start Page: 536
    End Page: 539
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/bioinformatics/btab658
    Best OA location URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10060715/pdf/btab658.pdf
    Citation Count: 27
  • Retro-Walking and Cholinergic Network Correlates in Parkinson’s Disease
    2025
    Summary Details
    OPEN
    Title: Retro-Walking and Cholinergic Network Correlates in Parkinson’s Disease
    Author(s): Alexis Griggs, Giulia Carli, Taylor Brown, Prabesh Kanel, Stiven Roytman, Chatkaew Pongmala, Miriam van Emde Boas, Nicolaas I. Bohnen
    Journal Name: Journal of Movement Disorders
    Publisher: The Korean Movement Disorder Society
    Vol: 18
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.14802/jmd.25109
    Best OA location URL: https://doi.org/10.14802/jmd.25109
    Citation Count: 0
  • Is Freezing of Gait in Parkinson's Disease a Result of Multiple Gait Impairments? Implications for Treatment
    2012
    Summary Details
    OPEN
    Title: Is Freezing of Gait in Parkinson's Disease a Result of Multiple Gait Impairments? Implications for Treatment
    Author(s): Meir Plotnik, Nir Giladi, Jeffrey M. Hausdorff
    Journal Name: Parkinson's Disease
    Publisher: Wiley
    Vol: 2012
    Issue #:
    Start Page: 1
    End Page: 8
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1155/2012/459321
    Best OA location URL: https://downloads.hindawi.com/journals/pd/2012/459321.pdf
    Citation Count: 110
  • Is the MC1R variant p.R160W associated with Parkinson's?
    2015
    Summary Details
    OPEN
    Title: Is the MC1R variant p.R160W associated with Parkinson's?
    Author(s): Steven Lubbe, Valentina Escott‐Price, Alexis Brice, Thomas Gasser, John Hardy, Peter Heutink, Manu Sharma, Nicholas Wood, Mike A. Nalls, Andrew Singleton, Nigel Williams, Huw R. Morris
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 79
    Issue #: 1
    Start Page: 159
    End Page: 161
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.24527
    Best OA location URL: http://doi.org/10.1002/ana.24527
    Citation Count: 18
  • Dopaminergic Retinal Cell Loss and Visual Dysfunction in Parkinson Disease
    2020
    Summary Details
    OPEN
    Title: Dopaminergic Retinal Cell Loss and Visual Dysfunction in Parkinson Disease
    Author(s): Isabel Ortuño‐Lizarán, Xavier Sánchez‐Sáez, Pedro Lax, Geidy E. Serrano, Thomas G. Beach, Charles H. Adler, Nicolás Cuenca
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 88
    Issue #: 5
    Start Page: 893
    End Page: 906
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.25897
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.25897
    Citation Count: 87
  • A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
    2022
    Summary Details
    OPEN
    Title: A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
    Author(s): Edmundo G. Vides, Ayan Adhikari, Claire Y Chiang, Paweł Lis, Elena Purlyte, Charles Limouse, Justin L Shumate, Elena Spínola-Lasso, Herschel S. Dhekne, Dario R. Alessi, Suzanne R. Pfeffer
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Vol: 11
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.7554/elife.79771
    Best OA location URL: https://doi.org/10.7554/elife.79771
    Citation Count: 53
  • Altered dynamics of visual contextual interactions in Parkinson’s disease
    2019
    Summary Details
    OPEN
    Title: Altered dynamics of visual contextual interactions in Parkinson’s disease
    Author(s): M. Isabel Vanegas, Annabelle Blangero, James E. Galvin, Alessandro Di Rocco, Angelo Quartarone, Maria Felice Ghilardi, Simon P. Kelly
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 5
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-019-0085-5
    Best OA location URL: https://www.nature.com/articles/s41531-019-0085-5.pdf
    Citation Count: 9
  • New insights from a Malaysian real-world deep brain stimulation cohort
    2024
    Summary Details
    OPEN
    Title: New insights from a Malaysian real-world deep brain stimulation cohort
    Author(s): Alfand Marl F. Dy Closas, Ai Huey Tan, Yi Wen Tay, Jia Wei Hor, Tzi Shin Toh, Jia Lun Lim, Choey Yee Lew, Chun Yoong Cham, Carolyn Chue Wai Yim, Kok Yoon Chee, Chong Guan Ng, Lei Cheng Lit, A. Anuar, Lara M. Lange, Zih‐Hua Fang, Sara Bandrés‐Ciga, Katja Lohmann, Christine Klein, Azlina Ahmad, Kalai Arasu Muthusamy, Shen‐Yang Lim
    Journal Name: Journal of Parkinson’s Disease
    Publisher: SAGE Publications
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1177/1877718x241297715
    Best OA location URL: https://doi.org/10.1177/1877718x241297715
    Citation Count: 0
  • Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients
    2017
    Summary Details
    OPEN
    Title: Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients
    Author(s): Andrea M. Kälin, Min Tae M Park, M. Mallar Chakravarty, Jason P. Lerch, Lars Michels, Clemens Schroeder, Sarah D. Broicher, Spyros Kollias, Roger M. Nitsch, Anton Gietl, Paul G. Unschuld, Christoph Höck, Sandra E. Leh
    Journal Name: Frontiers in Aging Neuroscience
    Publisher: Frontiers Media SA
    Vol: 9
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnagi.2017.00038
    Best OA location URL: https://doi.org/10.3389/fnagi.2017.00038
    Citation Count: 58
  • Genome-wide case-only analysis of gene-gene interactions with known Parkinson’s disease risk variants reveals link between LRRK2 and SYT10
    2023
    Summary Details
    OPEN
    Title: Genome-wide case-only analysis of gene-gene interactions with known Parkinson’s disease risk variants reveals link between LRRK2 and SYT10
    Author(s): Milda Aleknonytė‐Resch, Joanne Trinh, Hampton L. Leonard, Sylvie Delcambre, Elsa Leitão, Dongbing Lai, Semra Smajić, Avi Orr‐Urtreger, Avner Thaler, Cornelis Blauwendraat, Arunabh Sharma, Mary B. Makarious, Jonggeol Jeff Kim, Julie Lake, Pegah Rahmati, Sandra Freitag‐Wolf, Philip Seibler, Tatiana Foroud, Andrew Singleton, Anne Grünewald, Frank J. Kaiser, Christine Klein, Michael Krawczak, Astrid Dempfle
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 9
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-023-00550-9
    Best OA location URL: https://www.nature.com/articles/s41531-023-00550-9.pdf
    Citation Count: 5
  • Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1
    2013
    Summary Details
    OPEN
    Title: Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1
    Author(s): Gregory C. Luerman, Chuong Nguyen, Harry Samaroo, Paula Loos, Hualin Simon Xi, Andres Hurtado‐Lorenzo, Elie Needle, G. Stephen Noell, Paul Galatsis, John Dunlop, Kieran F. Geoghegan, Warren D. Hirst
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 128
    Issue #: 4
    Start Page: 561
    End Page: 576
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/jnc.12483
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12483
    Citation Count: 63
  • Characterization of age-related microstructural changes in locus coeruleus and substantia nigra pars compacta
    2019
    Summary Details
    OPEN
    Title: Characterization of age-related microstructural changes in locus coeruleus and substantia nigra pars compacta
    Author(s): Jason Langley, Sana Hussain, Justino J. Flores, Ilana J. Bennett, Xiaoping Hu
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 87
    Issue #:
    Start Page: 89
    End Page: 97
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2019.11.016
    Best OA location URL: https://arxiv.org/pdf/1911.11336
    Citation Count: 46
  • Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and aging mice
    2020
    Summary Details
    OPEN
    Title: Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and aging mice
    Author(s): Natalia Ninkina, Tatiana Tarasova, Kirill Chaprov, Andrei Roman, Michail S. Kukharsky, Л. Г. Колик, Ruslan Ovchinnikov, A. A. Ustyugov, А. Д. Дурнев, Vladimir L. Buchman
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 91
    Issue #:
    Start Page: 76
    End Page: 87
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2020.02.026
    Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2020.02.026
    Citation Count: 29
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