1376 - 1400 of 8620 Results
Title
Year
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OPENTitle: A soluble α-synuclein construct forms a dynamic tetramerJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 108Issue #: 43Start Page: 17797End Page: 17802Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1113260108Citation Count: 445
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OPENTitle: Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 41Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1309991110Best OA location URL: http://europepmc.org/articles/PMC3799334Citation Count: 175
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OPENTitle: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegenerationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 110Issue #: 1Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1217296110Best OA location URL: https://www.pnas.org/content/pnas/110/1/300.full.pdfCitation Count: 115
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 114
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OPENTitle: Parkinson disease-associated mutation R1441H in LRRK2 prolongs the “active state” of its GTPase domainJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 11Start Page: 4055End Page: 4060Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1323285111Best OA location URL: https://www.pnas.org/content/pnas/111/11/4055.full.pdfCitation Count: 109
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OPENTitle: Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 7Start Page: 2626End Page: 2631Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1318306111Best OA location URL: https://www.pnas.org/content/pnas/111/7/2626.full.pdfCitation Count: 350
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OPENTitle: Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 29Start Page: 10732End Page: 10737Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321785111Best OA location URL: https://www.pnas.org/content/pnas/111/29/10732.full.pdfCitation Count: 301
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP12014OPENTitle: Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 18Start Page: 6804End Page: 6809Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1321845111Best OA location URL: https://infoscience.epfl.ch/handle/20.500.14299/104291Citation Count: 198
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 206
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo2015OPENTitle: CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivoJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 49Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1519430112Best OA location URL: https://www.pnas.org/content/pnas/112/49/E6818.full.pdfCitation Count: 29
- α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation2015OPENTitle: α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylationJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 15Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1417883112Best OA location URL: https://www.pnas.org/content/pnas/112/15/E1926.full.pdfCitation Count: 139
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OPENTitle: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 28Start Page: 8756End Page: 8761Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1509742112Best OA location URL: https://www.pnas.org/content/pnas/112/28/8756.full.pdfCitation Count: 184
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OPENTitle: Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 113Issue #: 34Start Page: 9587End Page: 9592Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1610099113Best OA location URL: https://www.pnas.org/content/pnas/113/34/9587.full.pdfCitation Count: 238
- Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons2016OPENTitle: Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 113Issue #: 47Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1608784113Best OA location URL: https://www.pnas.org/content/pnas/113/47/E7564.full.pdfCitation Count: 53
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OPENTitle: Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 114Issue #: 10Start Page: 2735End Page: 2740Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1621218114Best OA location URL: https://kclpure.kcl.ac.uk/portal/en/publications/fe4ac1f8-01d0-455f-938a-1a1dbc447b69Citation Count: 35
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OPENTitle: Nrf2 mitigates LRRK2- and α-synuclein–induced neurodegeneration by modulating proteostasisJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 114Issue #: 5Start Page: 1165End Page: 1170Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1522872114Best OA location URL: https://www.pnas.org/content/pnas/114/5/1165.full.pdfCitation Count: 113
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OPENTitle: Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 115Issue #: 11Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1713849115Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5856519Citation Count: 185
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OPENTitle: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 115Issue #: 22Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1718946115Best OA location URL: https://www.pnas.org/content/pnas/115/22/E5164.full.pdfCitation Count: 109
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OPENTitle: Maladaptive striatal plasticity in l-DOPA-induced dyskinesiaJournal Name: Progress in Brain ResearchPublisher: ElsevierVol:Issue #:Start Page: 209End Page: 233Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s0079-6123(10)83011-0Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2930606Citation Count: 198
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OPENTitle: Pharmacologically distinct pramipexole-mediated akinesia vs. risk-taking in a rat model of Parkinson's diseaseJournal Name: Progress in Neuro-Psychopharmacology and Biological PsychiatryPublisher: Elsevier BVVol: 70Issue #:Start Page: 77End Page: 84Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.pnpbp.2016.05.004Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5410378Citation Count: 25
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OPENTitle: Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasmJournal Name: Protein Engineering, Design and SelectionPublisher: Oxford University Press (OUP)Vol: 23Issue #: 6Start Page: 489End Page: 498Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/protein/gzq022Best OA location URL: https://academic.oup.com/peds/article-pdf/23/6/489/17494272/gzq022.pdfCitation Count: 58
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OPENTitle: mzStudio: A Dynamic Digital Canvas for User-Driven Interrogation of Mass Spectrometry DataJournal Name: ProteomesPublisher: MDPI AGVol: 5Issue #: 3Start Page: 20End Page: 20Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/proteomes5030020Best OA location URL: https://www.mdpi.com/2227-7382/5/3/20/pdf?version=1501590909Citation Count: 25
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OPENTitle: Proteomic identification of proteins in the human brain: Towards a more comprehensive understanding of neurodegenerative diseaseJournal Name: PROTEOMICS – Clinical ApplicationsPublisher: WileyVol: 2Issue #: 10-11Start Page: 1484End Page: 1497Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/prca.200800043Best OA location URL: https://europepmc.org/articles/pmc3142616?pdf=renderCitation Count: 27
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OPENTitle: The avascular zone and neuronal remodeling of the fovea in Parkinson diseaseJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 2Issue #: 2Start Page: 196End Page: 201Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.146Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.146Citation Count: 41
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OPENTitle: α‐synuclein conformational antibodies fused to penetratin are effective in models of Lewy body diseaseJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 3Issue #: 8Start Page: 588End Page: 606Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.321Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.321Citation Count: 39