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  • Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease
    2022
    Summary Details
    RESTRICTED
    Title: Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease
    Author(s): Danna Jennings, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, Jennifer C. Sasaki, René Meisner, Dolores Diaz, Hilda Solanoy, Xiang Wang, Elvira Negrou, Vitaliy V. Bondar, Rajarshi Ghosh, Michael T. Maloney, Nicholas E. Propson, Yuda Zhu, Romeo Maciuca, Laura Harris, Angela Kay, Peter A. LeWitt, T. Alex King, Drew S. Kern, Aaron Ellenbogen, Ira Goodman, Andrew Siderowf, Jason Aldred, Omid Omidvar, Shababa T. Masoud, Sonnet S. Davis, Annie Arguello, Anthony A. Estrada, Javier de Vicente, Zachary K. Sweeney, Giuseppe Astarita, Marie T. Borin, Bradley K. Wong, Harvey Wong, Hoang N. Nguyen, Kimberly Scearce‐Levie, Carole Ho, Matthew D. Troyer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 14
    Issue #: 648
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.abj2658
    Best OA location URL:
    Citation Count: 163
  • Structure of the second phosphoubiquitin–binding site in parkin
    2022
    Summary Details
    OPEN
    Title: Structure of the second phosphoubiquitin–binding site in parkin
    Author(s): Rayan Fakih, Véronique Sauvé, Kalle Gehring
    Journal Name: Journal of Biological Chemistry
    Publisher: Elsevier BV
    Vol: 298
    Issue #: 7
    Start Page: 102114
    End Page: 102114
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.jbc.2022.102114
    Best OA location URL: http://www.jbc.org/article/S0021925822005555/pdf
    Citation Count: 21
  • The immunology of Parkinson’s disease
    2022
    Summary Details
    RESTRICTED
    Title: The immunology of Parkinson’s disease
    Author(s): Biqing Zhu, Dominic Yin, Hongyu Zhao, Le Zhang
    Journal Name: Seminars in Immunopathology
    Publisher: Springer Science and Business Media LLC
    Vol: 44
    Issue #: 5
    Start Page: 659
    End Page: 672
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1007/s00281-022-00947-3
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00281-022-00947-3.pdf
    Citation Count: 37
  • Evaluating the Use of Digital Biomarkers to Test Treatment Effects on Cognition and Movement in Patients with Lewy Body Dementia
    2022
    Summary Details
    OPEN
    Title: Evaluating the Use of Digital Biomarkers to Test Treatment Effects on Cognition and Movement in Patients with Lewy Body Dementia
    Author(s): Jian Wang, Chakib Battioui, Andrew McCarthy, Xiangnan Dang, Hui Zhang, Albert Man, Jasmine Zou, Jeffrey A. Kyle, Leanne Munsie, Melissa Pugh, Kevin Biglan
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Vol: 12
    Issue #: 6
    Start Page: 1991
    End Page: 2004
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-213126
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd213126?id=journal-of-parkinsons-disease%2Fjpd213126
    Citation Count: 9
  • Longitudinal Cohort Study of Verbatim-Reported Postural Instability Symptoms as Outcomes for Online Parkinson’s Disease Trials
    2022
    Summary Details
    OPEN
    Title: Longitudinal Cohort Study of Verbatim-Reported Postural Instability Symptoms as Outcomes for Online Parkinson’s Disease Trials
    Author(s): Ira Shoulson, Lakshmi Arbatti, Abhishek Hosamath, Shirley Eberly, David Oakes
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Vol: 12
    Issue #: 6
    Start Page: 1969
    End Page: 1978
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-223274
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd223274?id=journal-of-parkinsons-disease%2Fjpd223274
    Citation Count: 9
  • Predicting the onset of freezing of gait in Parkinson’s disease
    2022
    Summary Details
    OPEN
    Title: Predicting the onset of freezing of gait in Parkinson’s disease
    Author(s): Fengting Wang, Yixin Pan, Miao Zhang, Kejia Hu
    Journal Name: BMC Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 22
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12883-022-02713-2
    Best OA location URL: https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/s12883-022-02713-2
    Citation Count: 18
  • PRKRAP1 and Other Pseudogenes in Movement Disorders: The Troublemakers in Genetic Analyses Are More Than Genomic Fossils
    2022
    Summary Details
    OPEN
    Title: PRKRAP1 and Other Pseudogenes in Movement Disorders: The Troublemakers in Genetic Analyses Are More Than Genomic Fossils
    Author(s): Francesca Magrinelli, Katja Lohmann
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol: 9
    Issue #: 5
    Start Page: 698
    End Page: 702
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/mdc3.13499
    Best OA location URL: https://doi.org/10.1002/mdc3.13499
    Citation Count: 2
  • Quantitative Digitography Measures Motor Symptoms and Disease Progression in Parkinson’s Disease
    2022
    Summary Details
    OPEN
    Title: Quantitative Digitography Measures Motor Symptoms and Disease Progression in Parkinson’s Disease
    Author(s): Kevin B. Wilkins, Matthew N. Petrucci, Yasmine M. Kehnemouyi, Anca Velisar, Katie Han, Gerrit Orthlieb, Megan H. Trager, Johanna O’Day, Sudeep Aditham, Helen Brontë‐Stewart
    Journal Name: Journal of Parkinson's Disease
    Publisher: SAGE Publications
    Vol: 12
    Issue #: 6
    Start Page: 1979
    End Page: 1990
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3233/jpd-223264
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd223264?id=journal-of-parkinsons-disease%2Fjpd223264
    Citation Count: 13
  • Association of Structural Measurements of Brain Reserve With Motor Progression in Patients With Parkinson Disease
    2022
    Summary Details
    OPEN
    Title: Association of Structural Measurements of Brain Reserve With Motor Progression in Patients With Parkinson Disease
    Author(s): Linbo Wang, Ping Wu, Peter Brown, Wei Zhang, Fengtao Liu, Yan Han, Chuantao Zuo, Wei Cheng, Jianfeng Feng
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 99
    Issue #: 10
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000200814
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7613818
    Citation Count: 13
  • Disease Progression in Multiple System Atrophy—Novel Modeling Framework and Predictive Factors
    2022
    Summary Details
    OPEN
    Title: Disease Progression in Multiple System Atrophy—Novel Modeling Framework and Predictive Factors
    Author(s): Line Kühnel, Lars Lau Rakêt, Daniel Oudin Åström, Anna‐Karin Berger, Ingeborg Helbech Hansen, Florian Krismer, Gregor K. Wenning, Klaus Seppi, Werner Poewe, JoséLuis Molinuevo
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 37
    Issue #: 8
    Start Page: 1719
    End Page: 1727
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mds.29077
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29077
    Citation Count: 9
  • Interventions for preventing falls in Parkinson's disease
    2022
    Summary Details
    RESTRICTED
    Title: Interventions for preventing falls in Parkinson's disease
    Author(s): Natalie E. Allen, Colleen G. Canning, Lorena Rosa S. Almeida, Bastiaan R. Bloem, S.H.J. Keus, Niklas Löfgren, Alice Nieuwboer, Geert Verheyden, Tiê Parma Yamato, Catherine Sherrington
    Journal Name: Cochrane Database of Systematic Reviews
    Publisher: Wiley
    Vol: 2022
    Issue #: 8
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/14651858.cd011574.pub2
    Best OA location URL: https://repository.ubn.ru.nl/bitstream/handle/2066/252084/1/252084.pdf
    Citation Count: 38
  • Long‐term independence and quality of life after subthalamic stimulation in Parkinson disease
    2022
    Summary Details
    OPEN
    Title: Long‐term independence and quality of life after subthalamic stimulation in Parkinson disease
    Author(s): Anna Castrioto, Bettina Debû, Émilie Cousin, Pierre Pélissier, Eugénie Lhommée, Amélie Bichon, Emmanuelle Schmitt, Andrea Kistner, Sara Meoni, Éric Seigneuret, Stéphan Chabardès, Paul Krack, Elena Moro, Valérie Fraix
    Journal Name: European Journal of Neurology
    Publisher: Wiley
    Vol: 29
    Issue #: 9
    Start Page: 2645
    End Page: 2653
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1111/ene.15436
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543065
    Citation Count: 6
  • Structure–Functional Selectivity Relationship Studies on A-86929 Analogs and Small Aryl Fragments toward the Discovery of Biased Dopamine D1 Receptor Agonists
    2022
    Summary Details
    RESTRICTED
    Title: Structure–Functional Selectivity Relationship Studies on A-86929 Analogs and Small Aryl Fragments toward the Discovery of Biased Dopamine D1 Receptor Agonists
    Author(s): Haoxi Li, Rosa Mirabel, Joseph Zimmerman, Ion Ghiviriga, Darian K. Phidd, Nicole A. Horenstein, Nikhil M. Urs
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 13
    Issue #: 12
    Start Page: 1818
    End Page: 1831
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.2c00235
    Best OA location URL:
    Citation Count: 3
  • Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease
    2022
    Summary Details
    OPEN
    Title: Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease
    Author(s): Becky C. Carlyle, Robert R. Kitchen, Zoe A. Mattingly, Amanda M. Celia, Bianca A. Trombetta, Sudeshna Das, Bradley T. Hyman, Pia Kivisäkk, Steven E. Arnold
    Journal Name: Frontiers in Neurology
    Publisher: Frontiers Media SA
    Vol: 13
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fneur.2022.889647
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fneur.2022.889647/pdf
    Citation Count: 38
  • Unraveling trajectories of diffusive particles on networks
    2022
    Summary Details
    OPEN
    Title: Unraveling trajectories of diffusive particles on networks
    Author(s): Yaohua Sun, Zexi Yu, Christopher J. Obara, Keshav Mittal, Jennifer Lippincott‐Schwartz, Elena F. Koslover
    Journal Name: Physical Review Research
    Publisher: American Physical Society (APS)
    Vol: 4
    Issue #: 2
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1103/physrevresearch.4.023182
    Best OA location URL: http://link.aps.org/pdf/10.1103/PhysRevResearch.4.023182
    Citation Count: 3
  • L-Dopa response, choreic dyskinesia, and dystonia in Perry syndrome
    2022
    Summary Details
    RESTRICTED
    Title: L-Dopa response, choreic dyskinesia, and dystonia in Perry syndrome
    Author(s): Jarosław Dulski, Catalina Cerquera‐Cleves, Łukasz Milanowski, Jolanta Kwiatek-Majkusiak, Dariusz Koziorowski, Owen A. Ross, Jolanta Pentela‐Nowicka, Jarosław Sławek, Zbigniew K. Wszołek
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 100
    Issue #:
    Start Page: 19
    End Page: 23
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2022.05.023
    Best OA location URL:
    Citation Count: 7
  • Olfaction and apathy in early idiopathic Parkinson's disease
    2022
    Summary Details
    RESTRICTED
    Title: Olfaction and apathy in early idiopathic Parkinson's disease
    Author(s): Alfonso Enrique Martinez-Nunez, Kaitie Latack, Miguel Situ-Kcomt, Abhimanyu Mahajan
    Journal Name: Journal of the Neurological Sciences
    Publisher: Elsevier BV
    Vol: 439
    Issue #:
    Start Page: 120314
    End Page: 120314
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.jns.2022.120314
    Best OA location URL:
    Citation Count: 3
  • Are Virtual Objective Assessments of Fall‐Risk Feasible and Safe for People with Parkinson's Disease?
    2022
    Summary Details
    OPEN
    Title: Are Virtual Objective Assessments of Fall‐Risk Feasible and Safe for People with Parkinson's Disease?
    Author(s): Mitra Afshari, Andrea V. Hernandez, Jorik Nonnekes, Bastiaan R. Bloem, Christopher G. Goetz
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol: 9
    Issue #: 6
    Start Page: 799
    End Page: 804
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mdc3.13494
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13494
    Citation Count: 8
  • Association of Olfactory Performance With Motor Decline and Age at Onset in People With Parkinson Disease and the LRRK2 G2019S Variant
    2022
    Summary Details
    OPEN
    Title: Association of Olfactory Performance With Motor Decline and Age at Onset in People With Parkinson Disease and the LRRK2 G2019S Variant
    Author(s): Rachel Saunders‐Pullman, Roberto A. Ortega, Cuiling Wang, Deborah Raymond, Sonya Elango, Katherine Leaver, Nikita Urval, Viktoriya Katsnelson, Rachel S. Gerber, Matthew Swan, Vicki Shanker, Roy N. Alcalay, Anat Mirelman, Michael C. Brumm, Helen Mejia‐Santana, Christopher S. Coffey, Kenneth Marek, Laurie J. Ozelius, Nir Giladi, Karen Marder, Susan Bressman
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 99
    Issue #: 8
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0000000000200737
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484727
    Citation Count: 8
  • ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
    2022
    Summary Details
    OPEN
    Title: ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
    Author(s): William Hancock‐Cerutti, Zheng Wu, Peng Xu, Narayana Yadavalli, Marianna Leonzino, Arun Kumar Tharkeshwar, Shawn M. Ferguson, Gerald S. Shadel, Pietro De Camilli
    Journal Name: Journal of Cell Biology
    Publisher: Rockefeller University Press
    Vol: 221
    Issue #: 7
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by, cc-by
    DOI - Digital Object Identifier: 10.1083/jcb.202106046
    Best OA location URL: https://rupress.org/jcb/article-pdf/221/7/e202106046/1434249/jcb_202106046.pdf
    Citation Count: 73
  • Practical pearls to improve the efficacy and tolerability of levodopa in Parkinson’s disease
    2022
    Summary Details
    RESTRICTED
    Title: Practical pearls to improve the efficacy and tolerability of levodopa in Parkinson’s disease
    Author(s): Abhishek Lenka, Gianluca Di Maria, Guillaume Lamotte, Laxman Bahroo, Joseph Jankovic
    Journal Name: Expert Review of Neurotherapeutics
    Publisher: Informa UK Limited
    Vol: 22
    Issue #: 6
    Start Page: 489
    End Page: 498
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1080/14737175.2022.2091436
    Best OA location URL:
    Citation Count: 4
  • Subacute tremor and ataxia: Diligence in pursuit of a diagnosis
    2022
    Summary Details
    RESTRICTED
    Title: Subacute tremor and ataxia: Diligence in pursuit of a diagnosis
    Author(s): Jessica Frey, Jon B. Toledo, Adolfo Ramirez‐Zamora, Irene A. Malaty
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 104
    Issue #:
    Start Page: 129
    End Page: 131
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2022.05.016
    Best OA location URL:
    Citation Count: 1
  • Targeted copy number variant identification across the neurodegenerative disease spectrum
    2022
    Summary Details
    OPEN
    Title: Targeted copy number variant identification across the neurodegenerative disease spectrum
    Author(s): Allison A. Dilliott, Kristina K. Zhang, Jian Wang, Agessandro Abrahão, Malcolm A. Binns, Sandra E. Black, Michael Borrie, Dar Dowlatshahi, Elizabeth Finger, Corinne E. Fischer, Andrew Frank, Morris Freedman, David A. Grimes, Ayman Hassan, Mandar Jog, Sanjeev Kumar, Anthony E. Lang, Jennifer Mandzia, Mario Masellis, Stephen Pasternak, Bruce G. Pollock, Tarek K. Rajji, Ekaterina Rogaeva, Demetrios J. Sahlas, Gustavo Saposnik, Christine Sato, Dallas Seitz, Christen Shoesmith, Thomas Steeves, Richard H. Swartz, Brian Tan, David F. Tang‐Wai, Maria Carmela Tartaglia, John Turnbull, Lorne Zinman, Robert A. Hegele
    Journal Name: Molecular Genetics & Genomic Medicine
    Publisher: Wiley
    Vol: 10
    Issue #: 8
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mgg3.1986
    Best OA location URL: https://ir.lib.uwo.ca/cgi/viewcontent.cgi?article=1101&context=neurosci_inst_pubs
    Citation Count: 4
  • Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting
    2022
    Summary Details
    OPEN
    Title: Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting
    Author(s): Lara Blömeke, Marlene Pils, Victoria Kraemer‐Schulien, Alexandra Dybala, Anja Schaffrath, Andreas Kulawik, Fabian Rehn, Anneliese Cousin, Volker Nischwitz, Johannes Willbold, Rebecca Zack, Thomas F. Tropea, Tuyen Bujnicki, Gültekin Tamgüney, Daniel Weintraub, David J. Irwin, Murray Grossman, David A. Wolk, John Q. Trojanowski, Oliver Bannach, Alice Chen‐Plotkin, Dieter Willbold
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-022-00330-x
    Best OA location URL: https://www.nature.com/articles/s41531-022-00330-x.pdf
    Citation Count: 26
  • A unifying model for the role of the ATG8 system in autophagy
    2022
    Summary Details
    OPEN
    Title: A unifying model for the role of the ATG8 system in autophagy
    Author(s): Thanh Ngoc Nguyen, Michael Lazarou
    Journal Name: Journal of Cell Science
    Publisher: The Company of Biologists
    Vol: 135
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1242/jcs.258997
    Best OA location URL: https://doi.org/10.1242/jcs.258997
    Citation Count: 18
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