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  • Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
    2018
    Summary Details
    OPEN
    Title: Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
    Author(s): Getaw Worku Hassen, Leo Kesner, Alfred Stracher, Abraham Shulman, Edward Rockenstein, Michael Mante, Anthony Adame, Cassia Overk, Robert A. Rissman, Eliezer Masliah
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-35729-1
    Best OA location URL: https://www.nature.com/articles/s41598-018-35729-1.pdf
    Citation Count: 24
  • Tau immunoreactivity in peripheral tissues of human aging and select tauopathies
    2018
    Summary Details
    OPEN
    Title: Tau immunoreactivity in peripheral tissues of human aging and select tauopathies
    Author(s): Brittany N. Dugger, Brittany Hoffman, Alex Scroggins, Geidy E. Serrano, Charles H. Adler, Holly A. Shill, Christine M. Belden, Marwan N. Sabbagh, John N. Caviness, Erika Driver Dunckley, Thomas G. Beach
    Journal Name: Neuroscience Letters
    Publisher: Elsevier BV
    Vol: 696
    Issue #:
    Start Page: 132
    End Page: 139
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neulet.2018.12.031
    Best OA location URL: https://europepmc.org/articles/pmc7357994?pdf=render
    Citation Count: 49
  • Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity
    2018
    Summary Details
    OPEN
    Title: Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity
    Author(s): Tobias Fehlmann, Thomas Laufer, Christina Backes, Mustafa Kahramann, Julia Alles, Ulrike Fischer, Marie Minet, Nicole Ludwig, Fabian Kern, Tim Kehl, Valentina Galata, Aneta Düsterloh, Hannah Schrörs, Jochen Kohlhaas, Robert Bals, Hanno Huwer, Lars Geffers, Rejko Krüger, Rudi Balling, Hans‐Peter Lenhof, Eckart Meese, Andreas Keller
    Journal Name: RNA Biology
    Publisher: Informa UK Limited
    Vol: 16
    Issue #: 1
    Start Page: 93
    End Page: 103
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1080/15476286.2018.1559689
    Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15476286.2018.1559689?needAccess=true
    Citation Count: 7
  • Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
    2018
    Summary Details
    OPEN
    Title: Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
    Author(s): Allison Kraus, Eri Saijo, Michael A. Metrick, Kathy L. Newell, Christina J. Sigurdson, Gianluigi Zanusso, Bernardino Ghetti, Byron Caughey
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 137
    Issue #: 4
    Start Page: 585
    End Page: 598
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-018-1947-3
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-018-1947-3.pdf
    Citation Count: 115
  • Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease
    2018
    Summary Details
    OPEN
    Title: Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease
    Author(s): Jingting Dai, Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong, Marla Gearing, James J. Lah, Allan I. Levey, Thomas S. Wingo, Nicholas T. Seyfried
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Vol: 11
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2018.00454
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2018.00454/pdf
    Citation Count: 68
  • Non-Dopaminergic Therapies
    2018
    Summary Details
    RESTRICTED
    Title: Non-Dopaminergic Therapies
    Author(s): John G. Nutt, Nicolaas I. Bohnen
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 8
    Issue #: s1
    Start Page: S73
    End Page: S78
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181472
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd181472?id=journal-of-parkinsons-disease%2Fjpd181472
    Citation Count: 7
  • Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies
    2018
    Summary Details
    RESTRICTED
    Title: Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies
    Author(s): Claire Henchcliffe, Malin Parmar
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 8
    Issue #: s1
    Start Page: S131
    End Page: S137
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181488
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd181488?id=journal-of-parkinsons-disease%2Fjpd181488
    Citation Count: 19
  • The Emerging Evidence of the Parkinson Pandemic
    2018
    Summary Details
    RESTRICTED
    Title: The Emerging Evidence of the Parkinson Pandemic
    Author(s): E. Ray Dorsey, Todd Sherer, Michael S. Okun, Bastiaan R. Bloem
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 8
    Issue #: s1
    Start Page: S3
    End Page: S8
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181474
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd181474?id=journal-of-parkinsons-disease%2Fjpd181474
    Citation Count: 905
  • Updating Our Definitions of Parkinson’s Disease for a Molecular Age
    2018
    Summary Details
    RESTRICTED
    Title: Updating Our Definitions of Parkinson’s Disease for a Molecular Age
    Author(s): Alice Chen‐Plotkin, Henrik Zetterberg
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 8
    Issue #: s1
    Start Page: S53
    End Page: S57
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.3233/jpd-181487
    Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd181487?id=journal-of-parkinsons-disease%2Fjpd181487
    Citation Count: 8
  • Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson’s Disease with Mild Cognitive Impairment
    2018
    Summary Details
    OPEN
    Title: Entorhinal Cortex Atrophy in Early, Drug-naive Parkinson’s Disease with Mild Cognitive Impairment
    Author(s): Xiuqin Jia, Zhijiang Wang, Tao Yang, Ying Li, Shuai Gao, Guorong Wu, Tao Jiang, Peipeng Liang
    Journal Name: Aging and disease
    Publisher: Aging and Disease
    Vol: 10
    Issue #: 6
    Start Page: 1221
    End Page: 1221
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.14336/ad.2018.1116
    Best OA location URL: http://www.aginganddisease.org/EN/article/downloadArticleFile.do?attachType=PDF&id=147799
    Citation Count: 42
  • Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease
    2018
    Summary Details
    OPEN
    Title: Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease
    Author(s): Claudia Cicognola, Gunnar Brinkmalm, Jessica Wahlgren, Erik Portelius, Johan Gobom, Nicholas Cullen, Oskar Hansson, Lucilla Parnetti, Radu Constantinescu, Kristin R. Wildsmith, Hsu-Hsin Chen, Thomas G. Beach, Tammaryn Lashley, Henrik Zetterberg, Kaj Blennow, Kina Höglund
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 137
    Issue #: 2
    Start Page: 279
    End Page: 296
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-018-1948-2
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-018-1948-2.pdf
    Citation Count: 140
  • Deep brain stimulation of the substantia nigra for freezing of gait in Parkinson's disease: is it about stimulation frequency?
    2018
    Summary Details
    RESTRICTED
    Title: Deep brain stimulation of the substantia nigra for freezing of gait in Parkinson's disease: is it about stimulation frequency?
    Author(s): Daniel Weiß, Luka Milosevic, Alireza Gharabaghi
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 63
    Issue #:
    Start Page: 229
    End Page: 230
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.12.010
    Best OA location URL:
    Citation Count: 13
  • Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson’s disease
    2018
    Summary Details
    RESTRICTED
    Title: Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson’s disease
    Author(s): Katrina Albert, Merja H. Voutilainen, Andrii Domanskyi, Petteri Piepponen, Sari Ahola, Raimo K. Tuominen, Christopher T. Richie, Brandon K. Harvey, Mikko Airavaara
    Journal Name: Journal of Neuroscience Research
    Publisher: Wiley
    Vol: 97
    Issue #: 3
    Start Page: 346
    End Page: 361
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/jnr.24363
    Best OA location URL:
    Citation Count: 27
  • Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale‐2 in Parkinson's disease
    2018
    Summary Details
    OPEN
    Title: Comparative sensitivity of the MoCA and Mattis Dementia Rating Scale‐2 in Parkinson's disease
    Author(s): Taylor R. Hendershott, Delphine Zhu, Seoni Llanes, Cyrus P. Zabetian, Joseph F. Quinn, Karen L. Edwards, James B. Leverenz, Thomas J. Montine, Brenna Cholerton, Kathleen L. Poston
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 34
    Issue #: 2
    Start Page: 285
    End Page: 291
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27575
    Best OA location URL: https://europepmc.org/articles/pmc6532623?pdf=render
    Citation Count: 17
  • Immune system responses in Parkinson's disease: Early and dynamic
    2018
    Summary Details
    RESTRICTED
    Title: Immune system responses in Parkinson's disease: Early and dynamic
    Author(s): Malú G. Tansey, Marina Romero‐Ramos
    Journal Name: European Journal of Neuroscience
    Publisher: Wiley
    Vol: 49
    Issue #: 3
    Start Page: 364
    End Page: 383
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1111/ejn.14290
    Best OA location URL: https://europepmc.org/articles/pmc6391192?pdf=render
    Citation Count: 107
  • Regional gray matter changes and age predict individual treatment response in Parkinson's disease
    2018
    Summary Details
    OPEN
    Title: Regional gray matter changes and age predict individual treatment response in Parkinson's disease
    Author(s): Tommaso Ballarini, Karsten Mueller, Franziska Albrecht, Filip Růžička, Ondřej Bezdíček, Evžen Růžička, Jan Roth, Josef Vymazal, Robert Jech, Matthias L. Schroeter
    Journal Name: NeuroImage: Clinical
    Publisher: Elsevier BV
    Vol: 21
    Issue #:
    Start Page: 101636
    End Page: 101636
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1016/j.nicl.2018.101636
    Best OA location URL: https://doi.org/10.1016/j.nicl.2018.101636
    Citation Count: 25
  • Self-reported physical activity levels and clinical progression in early Parkinson's disease
    2018
    Summary Details
    RESTRICTED
    Title: Self-reported physical activity levels and clinical progression in early Parkinson's disease
    Author(s): Amy W. Amara, Lana M. Chahine, Nicholas Seedorff, Chelsea Caspell‐Garcia, Christopher S. Coffey, Tanya Simuni
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 61
    Issue #:
    Start Page: 118
    End Page: 125
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2018.11.006
    Best OA location URL:
    Citation Count: 72
  • Non-motor predictors of freezing of gait in Parkinson’s disease
    2018
    Summary Details
    OPEN
    Title: Non-motor predictors of freezing of gait in Parkinson’s disease
    Author(s): Sarah J. Banks, Ece Bayram, Guogen Shan, Denise R. LaBelle, Brent Bluett
    Journal Name: Gait & Posture
    Publisher: Elsevier BV
    Vol: 68
    Issue #:
    Start Page: 311
    End Page: 316
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.gaitpost.2018.12.009
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6773271
    Citation Count: 52
  • A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    2018
    Summary Details
    OPEN
    Title: A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
    Author(s): Hongjun Fu, Andrea Possenti, Rosie Freer, Yoshikazu Nakano, Nancy C. Hernandez Villegas, Maoping Tang, Paula Victoria Maglio Cauhy, Benjamin Lassus, Shuo Chen, Stephanie L. Fowler, Helen Y. Figueroa, Edward D. Huey, Gail V.W. Johnson, Michele Vendruscolo, Karen Duff
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 22
    Issue #: 1
    Start Page: 47
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-018-0298-7
    Best OA location URL: https://doi.org/10.17863/cam.42071
    Citation Count: 210
  • Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB
    2018
    Summary Details
    OPEN
    Title: Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB
    Author(s): Run Yan, Jie Zhang, Hye-Jin Park, Eun Su Park, Stephanie Oh, Haiyan Zheng, Eunsung Junn, Michael Voronkov, Jeffry B. Stock, M. Maral Mouradian
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 115
    Issue #: 51
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1073/pnas.1813365115
    Best OA location URL: https://www.pnas.org/content/pnas/115/51/E12053.full.pdf
    Citation Count: 77
  • Characterizing patient compliance over six months in remote digital trials of Parkinson’s and Huntington disease
    2018
    Summary Details
    OPEN
    Title: Characterizing patient compliance over six months in remote digital trials of Parkinson’s and Huntington disease
    Author(s): Shani Cohen, Zeev Waks, Jordan J. Elm, Mark Forrest Gordon, Igor D. Grachev, Leehee Navon-Perry, Shai Fine, Iris Grossman, Spyros Papapetropoulos, Juha‐Matti Savola
    Journal Name: BMC Medical Informatics and Decision Making
    Publisher: Springer Science and Business Media LLC
    Vol: 18
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12911-018-0714-7
    Best OA location URL: https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-018-0714-7
    Citation Count: 37
  • The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
    2018
    Summary Details
    OPEN
    Title: The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
    Author(s): Veronika E. Neubrand, Irene Forte‐Lago, Marta Caro, Mario Delgado
    Journal Name: Journal of Neuroinflammation
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12974-018-1386-z
    Best OA location URL: https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-018-1386-z
    Citation Count: 14
  • CoREST Complex-Selective Histone Deacetylase Inhibitors Show Prosynaptic Effects and an Improved Safety Profile To Enable Treatment of Synaptopathies
    2018
    Summary Details
    OPEN
    Title: CoREST Complex-Selective Histone Deacetylase Inhibitors Show Prosynaptic Effects and an Improved Safety Profile To Enable Treatment of Synaptopathies
    Author(s): Nathan O. Fuller, Antonella Pirone, Berkley A. Lynch, Michael C. Hewitt, Maria S. Quinton, Timothy D. McKee, Magnus Ivarsson
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 10
    Issue #: 3
    Start Page: 1729
    End Page: 1743
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00620
    Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00620
    Citation Count: 41
  • Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons
    2018
    Summary Details
    OPEN
    Title: Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons
    Author(s): Sarah A. McClymont, Paul W. Hook, Alexandra I. Soto, Xylena Reed, William D. Law, Samuel J. Kerans, Eric L. Waite, Nicole Briceno, Joseph F. Thole, Michael G. Heckman, Nancy N. Diehl, Zbigniew K. Wszołek, Cedric Moore, Heng Zhu, Jennifer A. Akiyama, Diane E. Dickel, Axel Visel, L Pennacchio, Owen A. Ross, M Beer, Andrew S. McCallion
    Journal Name: The American Journal of Human Genetics
    Publisher: Elsevier BV
    Vol: 103
    Issue #: 6
    Start Page: 874
    End Page: 892
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.ajhg.2018.10.018
    Best OA location URL: http://www.cell.com/article/S0002929718303707/pdf
    Citation Count: 38
  • A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's disease
    2018
    Summary Details
    OPEN
    Title: A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's disease
    Author(s): Madeleine Kristiansen, Jodi Maple‐Grødem, Guido Alves, Sampath Arepalli, Dena Hernández, Hirotaka Iwaki, Mike A. Nalls, Andrew Singleton, Ole‐Bjørn Tysnes, Mathias Toft, Lasse Pihlstrøm
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 34
    Issue #: 2
    Start Page: 298
    End Page: 299
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27555
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6379106
    Citation Count: 3
  • Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein
    2018
    Summary Details
    OPEN
    Title: Computational affinity maturation of camelid single-domain intrabodies against the nonamyloid component of alpha-synuclein
    Author(s): Sai Pooja Mahajan, Bunyarit Meksiriporn, Dujduan Waraho‐Zhmayev, Kevin B. Weyant, İlkay Koçer, David C. Butler, Anne Messer, Fernando A. Escobedo, Matthew P. DeLisa
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-35464-7
    Best OA location URL: https://www.nature.com/articles/s41598-018-35464-7.pdf
    Citation Count: 40
  • Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
    2018
    Summary Details
    OPEN
    Title: Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
    Author(s): Vivek Swarup, Flora I. Hinz, Jessica E. Rexach, K Noguchi, Hiroyoshi Toyoshiba, Akira Oda, Keisuke Hirai, Arjun Sarkar, Nicholas T. Seyfried, Chialin Cheng, Stephen J. Haggarty, Raffaele Ferrari, Jonathan D. Rohrer, Adaikalavan Ramasamy, John Hardy, Dena Hernandez, Mike A. Nalls, Andrew B. Singleton, John B. Kwok, Carol Dobson‐Stone, William S. Brooks, Peter R. Schofield, Glenda M. Halliday, John R. Hodges, Olivier Piguet, Lauren Bartley, Elizabeth Thompson, Eric Haan, Isabel Hernández, Agustı́n Ruiz, Merçé Boada, Barbara Borroni, Alessandro Padovani, Nigel J. Cairns, Carlos Cruchaga, Giuliano Binetti, Roberta Ghidoni, Luisa Benussi, Gianluigi Forloni, Diego Albani, Daniela Galimberti, Chiara Fenoglio, María Serpente, Elio Scarpini, Jordi Clarimón, Alberto Lleó, Rafael Blesa, María Landqvist Waldö, Karin Nilsson, Christer Nilsson, Ian R. Mackenzie, Ging‐Yuek Robin Hsiung, David M. A. Mann, Jordan Grafman, Christopher M. Morris, Johannes Attems, Timothy D. Griffiths, Ian G. McKeith, Alan Thomas, Evelyn Jaros, Pietro Pietrini, Edward D. Huey, Eric M. Wassermann, Michael Tierney, Atik Baborie, Pau Pástor, Sara Ortega‐Cubero, Cristina Razquín, Elena Alonso, Robert Perneczky, Janine Diehl‐Schmid, Panagiotis Alexopoulos, Alexander Kurz, Innocenzo Rainero, Elisa Rubino, Lorenzo Pinessi, Ekaterina Rogaeva, Peter St George‐Hyslop, Giacomina Rossi, Fabrizio Tagliavini, Giorgio Giaccone, James B. Rowe, Johannes C. M. Schlachetzki, James Uphill, John Collinge, Simon Mead, Adrian Danek, Vivianna M. Van Deerlin, Murray Grossman, John Q. Trojanowski, Stuart Pickering‐Brown, Parastoo Momeni, Julie van der Zee, Marc Cruts, Christine Van Broeckhoven, Stefano F. Cappa, Isabelle Leber, Alexis Brice, Didier Hannequin, Véronique Golfier, Martine Vercelletto, Benedetta Nacmias, Sandro Sorbi, Silvia Bagnoli, Irene Piaceri, Jørgen E. Nielsen, Lena E. Hjermind, Markus J. Riemenschneider, Manuel Mayhaus, Gilles Gasparoni, Sabrina Pichler, Bernd Ibach, Martin N. Rossor, Nick C. Fox, Jason D. Warren, Maria Grazia Spillantini, Huw R. Morris, Patrizia Rizzu, Peter Heutink, Julie S. Snowden, Sara Rollinson, Alexander Gerhard, Anna Richardson, Amalia C. Bruni, Raffaele Maletta, Francesca Frangipane, Chiara Cupidi, Livia Bernardi, Maria Anfossi, Maura Gallo, Maria Elena Conidi, Nicoletta Smirne, Rosa Rademakers, Matt Baker, Dennis W. Dickson, Neill R. Graff‐Radford, Ronald C. Petersen, David Knopman, Keith A. Josephs, Bradley F. Boeve, Joseph E. Parisi, Bruce L. Miller, Anna M. Karydas, Howard J. Rosen, William W. Seeley, John C. van Swieten, Elise G.P. Dopper, Harro Seelaar, Yolande A.L. Pijnenburg, Philip Scheltens, Giancarlo Logroscino, Rosa Capozzo, Valeria Novelli, Annibale Alessandro Puca, M. Franceschi, Alfredo Postiglione, Graziella Milan, Paolo Sorrentino, Mark Kristiansen, Huei‐Hsin Chiang, Caroline Graff, Florence Pasquier, Adeline Rollin, Vincent Deramecourt, Thibaud Lebouvier, Luigi Ferrucci, Dimitrios Kapogiannis, Murray Grossman, Vivianna M. Van Deerlin, John Q. Trojanowski, James J. Lah, Allan I. Levey, Shinichi Kondou, Daniel H. Geschwind
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 25
    Issue #: 1
    Start Page: 152
    End Page: 164
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41591-018-0223-3
    Best OA location URL: http://hdl.handle.net/2318/1783269
    Citation Count: 130
  • Normal and pathological neuronal distribution of the human mesencephalic locomotor region
    2018
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    Title: Normal and pathological neuronal distribution of the human mesencephalic locomotor region
    Author(s): Sophie B. Sébille, Anne‐Sophie Rolland, Matthieu Faillot, Fernando Pérez‐García, Antoine Collomb-Clerc, Brian Lau, Sylvie Dumas, Sara Fernandez Vidal, Marie‐Laure Welter, Chantal François, Éric Bardinet, Carine Karachi
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 34
    Issue #: 2
    Start Page: 218
    End Page: 227
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    DOI - Digital Object Identifier: 10.1002/mds.27578
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    Citation Count: 33
  • Understanding the role of genetic variability in LRRK2 in Indian population
    2018
    Summary Details
    OPEN
    Title: Understanding the role of genetic variability in LRRK2 in Indian population
    Author(s): Asha Kishore, Ashwin Ashok Kumar Sreelatha, Marc Sturm, Felix von‐Zweydorf, Lasse Pihlstrøm, Francesco Raimondi, Robert B. Russell, Peter Lichtner, Moinak Banerjee, Syam Krishnan, Roopa Rajan, Divya Kalikavil Puthenveedu, Sun Ju Chung, Peter Bauer, Olaf Rieß, Christian Johannes Gloeckner, Rejko Krüger, Thomas Gasser, Manu Sharma
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 34
    Issue #: 4
    Start Page: 496
    End Page: 505
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    Open Access(OA) Status: OPEN
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    DOI - Digital Object Identifier: 10.1002/mds.27558
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985845
    Citation Count: 14
  • Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβviaexosomes
    2018
    Summary Details
    OPEN
    Title: Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβviaexosomes
    Author(s): Javier Pacheco‐Quinto, Dana M. Clausen, Rocío Pérez‐González, Hui Peng, Austin Meszaros, Christopher B. Eckman, Efrat Levy, Elizabeth A. Eckman
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Vol: 33
    Issue #: 3
    Start Page: 3758
    End Page: 3771
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    DOI - Digital Object Identifier: 10.1096/fj.201801319r
    Best OA location URL: https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.201801319R
    Citation Count: 40
  • Renewed assessment of the risk of emergent advanced cell therapies to transmit neuroproteinopathies
    2018
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    Title: Renewed assessment of the risk of emergent advanced cell therapies to transmit neuroproteinopathies
    Author(s): Paul A. De Sousa, Diane Ritchie, Alison Green, Siddharthan Chandran, Richard Knight, Mark Head
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 137
    Issue #: 3
    Start Page: 363
    End Page: 377
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    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00401-018-1941-9
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-018-1941-9.pdf
    Citation Count: 6
  • Information processing deficit in older adults with HIV infection: A comparison with Parkinson’s disease.
    2018
    Summary Details
    OPEN
    Title: Information processing deficit in older adults with HIV infection: A comparison with Parkinson’s disease.
    Author(s): Saranya Sundaram, Eva M Müller-Oehring, Rosemary Fama, Helen M Brontë-Stewart, Kathleen L. Poston, Ryan Goodcase, Talora Martin, Varsha Prabhakar, Joshua Karpf, Tilman Schulte
    Journal Name: Neuropsychology
    Publisher: American Psychological Association (APA)
    Vol: 33
    Issue #: 2
    Start Page: 157
    End Page: 168
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    Open Access(OA) Status: OPEN
    License: publisher-specific, author manuscript
    DOI - Digital Object Identifier: 10.1037/neu0000500
    Best OA location URL: https://doi.org/10.1037/neu0000500
    Citation Count: 4
  • Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa)
    2018
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    Title: Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa)
    Author(s): Brit Mollenhauer, Johannes Zimmermann, Friederike Sixel‐Döring, Niels K. Focke, Tamara Wicke, Jens Ebentheuer, Martina Schaumburg, Elisabeth Lang, Tim Friede, Claudia Trenkwalder
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 34
    Issue #: 1
    Start Page: 67
    End Page: 77
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    DOI - Digital Object Identifier: 10.1002/mds.27492
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    Citation Count: 156
  • Intranasal delivery of hGDNF plasmid DNA nanoparticles results in long-term and widespread transfection of perivascular cells in rat brain
    2018
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    Title: Intranasal delivery of hGDNF plasmid DNA nanoparticles results in long-term and widespread transfection of perivascular cells in rat brain
    Author(s): Amirah E.-E. Aly, Brendan Harmon, Linas Padegimas, Ozge Sesenoglu‐Laird, Mark J. Cooper, David M. Yurek, Barbara L. Waszczak
    Journal Name: Nanomedicine: Nanotechnology, Biology and Medicine
    Publisher: Elsevier BV
    Vol: 16
    Issue #:
    Start Page: 20
    End Page: 33
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    DOI - Digital Object Identifier: 10.1016/j.nano.2018.11.006
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    Citation Count: 26
  • Wearable sensors for Parkinson’s disease: which data are worth collecting for training symptom detection models
    2018
    Summary Details
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    Title: Wearable sensors for Parkinson’s disease: which data are worth collecting for training symptom detection models
    Author(s): Luca Lonini, Andrew Dai, Nicholas Shawen, Tanya Simuni, Cynthia Poon, Leo Shimanovich, Margaret Daeschler, Roozbeh Ghaffari, John A. Rogers, Arun Jayaraman
    Journal Name: npj Digital Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
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    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41746-018-0071-z
    Best OA location URL: https://www.nature.com/articles/s41746-018-0071-z.pdf
    Citation Count: 177
  • Genetic analysis of neurodegenerative diseases in a pathology cohort
    2018
    Summary Details
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    Title: Genetic analysis of neurodegenerative diseases in a pathology cohort
    Author(s): Cornelis Blauwendraat, Olga Pletniková, Joshua T. Geiger, Natalie A. Murphy, Yevgeniya Abramzon, Gay Rudow, Adamantios Mamais, Marya S. Sabir, Barbara J. Crain, Sarah Ahmed, Liana S. Rosenthal, Catherine C. Bakker, Faraz Faghri, Ruth Chia, Jinhui Ding, Ted M. Dawson, Alexander Pantelyat, Marilyn S. Albert, Mike A. Nalls, Susan M. Resnick, Luigi Ferrucci, Mark Cookson, Argye E. Hillis, Juan C. Troncoso, Sonja W. Scholz
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 76
    Issue #:
    Start Page: 214.e1
    End Page: 214.e9
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    Open Access(OA) Status: OPEN
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    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2018.11.007
    Best OA location URL: https://europepmc.org/articles/pmc6391207?pdf=render
    Citation Count: 35
  • Joint modeling of multivariate longitudinal data and survival data in several observational studies of Huntington’s disease
    2018
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    Title: Joint modeling of multivariate longitudinal data and survival data in several observational studies of Huntington’s disease
    Author(s): Jeffrey D. Long, James A. Mills
    Journal Name: BMC Medical Research Methodology
    Publisher: Springer Science and Business Media LLC
    Vol: 18
    Issue #: 1
    Start Page:
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    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s12874-018-0592-9
    Best OA location URL: https://bmcmedresmethodol.biomedcentral.com/track/pdf/10.1186/s12874-018-0592-9.pdf
    Citation Count: 49
  • Benefits of pallidal stimulation in dystonia are linked to cerebellar volume and cortical inhibition
    2018
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    Title: Benefits of pallidal stimulation in dystonia are linked to cerebellar volume and cortical inhibition
    Author(s): Anna Fečíková, Robert Jech, Václav Čejka, Václav Čapek, Daniela Šťastná, Ivana Štětkářová, Karsten Mueller, Matthias L. Schroeter, Filip Růžička, Dušan Urgošík
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
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    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-34880-z
    Best OA location URL: https://www.nature.com/articles/s41598-018-34880-z.pdf
    Citation Count: 13
  • Recruitment of patients with de novo Parkinson disease: successful strategies in a randomized exercise clinical trial
    2018
    Summary Details
    OPEN
    Title: Recruitment of patients with de novo Parkinson disease: successful strategies in a randomized exercise clinical trial
    Author(s): Deborah A. Hall, Charity G. Moore, Cynthia L. Comella
    Journal Name: Trials
    Publisher: Springer Science and Business Media LLC
    Vol: 19
    Issue #: 1
    Start Page:
    End Page:
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    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/s13063-018-2958-z
    Best OA location URL: https://trialsjournal.biomedcentral.com/track/pdf/10.1186/s13063-018-2958-z
    Citation Count: 11
  • RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A
    2018
    Summary Details
    OPEN
    Title: RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A
    Author(s): Jesús Madero‐Pérez, Belén Fernández, Antonio Jesús Lara Ordóñez, Elena Fdez, Evy Lobbestael, Veerle Baekelandt, Sabine Hilfiker
    Journal Name: Frontiers in Molecular Neuroscience
    Publisher: Frontiers Media SA
    Vol: 11
    Issue #:
    Start Page:
    End Page:
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    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnmol.2018.00417
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnmol.2018.00417/pdf
    Citation Count: 43
  • Dietary Patterns, Physical Activity, Sleep, and Risk for Dementia and Cognitive Decline
    2018
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    Title: Dietary Patterns, Physical Activity, Sleep, and Risk for Dementia and Cognitive Decline
    Author(s): Chen Zhao, James M. Noble, Karen Marder, Jacob S. Hartman, Yian Gu, Nikolaos Scarmeas
    Journal Name: Current Nutrition Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 7
    Issue #: 4
    Start Page: 335
    End Page: 345
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    License:
    DOI - Digital Object Identifier: 10.1007/s13668-018-0247-9
    Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13668-018-0247-9.pdf
    Citation Count: 57
  • Evidence for increased completed suicide in first-degree relatives of LRRK2 G2019S mutation Parkinson’s disease
    2018
    Summary Details
    OPEN
    Title: Evidence for increased completed suicide in first-degree relatives of LRRK2 G2019S mutation Parkinson’s disease
    Author(s): Roberto A. Ortega, Mark Groves, Anat Mirelman, Roy N. Alcalay, Deborah Raymond, Sonya Elango, Helen Mejia‐Santana, Nir Giladi, Karen Marder, Susan Bressman, Rachel Saunders‐Pullman
    Journal Name: Journal of Neurology, Neurosurgery & Psychiatry
    Publisher: BMJ
    Vol: 90
    Issue #: 7
    Start Page: 843
    End Page: 844
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1136/jnnp-2018-319364
    Best OA location URL: https://europepmc.org/articles/pmc6506381?pdf=render
    Citation Count: 0
  • Magnetic resonance T1w/T2w ratio: A parsimonious marker for Parkinson disease
    2018
    Summary Details
    OPEN
    Title: Magnetic resonance T1w/T2w ratio: A parsimonious marker for Parkinson disease
    Author(s): Guangwei Du, Mechelle M. Lewis, Christopher T. Sica, Lan Kong, Xuemei Huang
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 85
    Issue #: 1
    Start Page: 96
    End Page: 104
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    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/ana.25376
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    Citation Count: 36
  • Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
    2018
    Summary Details
    OPEN
    Title: Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
    Author(s): Hsu-Hsin Chen, Peter Liu, Paul Auger, Seung-Hye Lee, Oskar Adolfsson, Lorianne Rey-Bellet, Julien Lafrance‐Vanasse, Brad A. Friedman, Maria Pihlgren, Andreas Muhs, Andrea Pfeifer, James A. Ernst, Gai Ayalon, Kristin R. Wildsmith, Thomas G. Beach, Marcel P. van der Brug
    Journal Name: Scientific Reports
    Publisher: Springer Science and Business Media LLC
    Vol: 8
    Issue #: 1
    Start Page:
    End Page:
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    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41598-018-35130-y
    Best OA location URL: https://www.nature.com/articles/s41598-018-35130-y.pdf
    Citation Count: 46
  • A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
    2018
    Summary Details
    OPEN
    Title: A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
    Author(s): Herschel S. Dhekne, Izumi Yanatori, Rachel C. Gomez, Francesca Tonelli, Federico Diez, Birgitt Schüle, Martin Steger, Dario R. Alessi, Suzanne R. Pfeffer
    Journal Name: eLife
    Publisher: eLife Sciences Publications, Ltd
    Vol: 7
    Issue #:
    Start Page:
    End Page:
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    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.7554/elife.40202
    Best OA location URL: https://doi.org/10.7554/elife.40202
    Citation Count: 227
  • Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
    2018
    Summary Details
    OPEN
    Title: Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates
    Author(s): Songye Li, Zhengxin Cai, Xiaoai Wu, Daniel Holden, Richard Pracitto, Michael Kapinos, Hong Gao, David Labaree, Nabeel Nabulsi, Richard E. Carson, Yiyun Huang
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 10
    Issue #: 3
    Start Page: 1544
    End Page: 1554
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschemneuro.8b00526
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6810685
    Citation Count: 95
  • Targeting the pedunculopontine nucleus in Parkinson's disease: Time to go back to the drawing board
    2018
    Summary Details
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    Title: Targeting the pedunculopontine nucleus in Parkinson's disease: Time to go back to the drawing board
    Author(s): Roger L. Albin, D. James Surmeier, Cecilia Tubert, Martin Sarter, Martijn L.T.M. Müller, Nicolaas I. Bohnen, William T. Dauer
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 12
    Start Page: 1871
    End Page: 1875
    Publication Date:
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    License:
    DOI - Digital Object Identifier: 10.1002/mds.27540
    Best OA location URL: http://deepblue.lib.umich.edu/bitstream/2027.42/147041/2/mds27540_am.pdf
    Citation Count: 19
  • Portrait of blood-derived extracellular vesicles in patients with Parkinson’s disease
    2018
    Summary Details
    OPEN
    Title: Portrait of blood-derived extracellular vesicles in patients with Parkinson’s disease
    Author(s): Jérôme Lamontagne‐Proulx, Isabelle St‐Amour, Richard Labib, Jérémie Pilon, Hélèna L. Denis, Nathalie Cloutier, Florence Roux‐Dalvai, Antony T. Vincent, Sarah Mason, Caroline H. Williams‐Gray, Anne‐Claire Duchez, Arnaud Droit, Steve Lacroix, Nicolas Dupré, Mélanie Langlois, Sylvain Chouinard, Michel Panisset, Roger A. Barker, Éric Boilard, Francesca Cicchetti
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 124
    Issue #:
    Start Page: 163
    End Page: 175
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2018.11.002
    Best OA location URL: https://www.repository.cam.ac.uk/bitstream/1810/287349/1/YNBDI_2018_257_Original_V0-2-4-72.pdf
    Citation Count: 43
  • RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
    2018
    Summary Details
    OPEN
    Title: RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
    Author(s): Jin‐Mi Heo, Alban Ordureau, Sharan Swarup, João A. Paulo, Kuang Shen, David M. Sabatini, J. Wade Harper
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 4
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc, cc-by-nc
    DOI - Digital Object Identifier: 10.1126/sciadv.aav0443
    Best OA location URL: https://advances.sciencemag.org/content/advances/4/11/eaav0443.full.pdf
    Citation Count: 162
  • Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure
    2018
    Summary Details
    OPEN
    Title: Serum Insulin-Like Growth Factor-1 in Parkinson's Disease; Study of Cerebrospinal Fluid Biomarkers and White Matter Microstructure
    Author(s): Farzaneh Ghazi Sherbaf, Bahram Mohajer, Amir Ashraf‐Ganjouei, Mahtab Mojtahed Zadeh, Ali Javinani, Hossein Sanjari Moghaddam, Mehdi Shirin Shandiz, Mohammad Hadi Aarabi
    Journal Name: Frontiers in Endocrinology
    Publisher: Frontiers Media SA
    Vol: 9
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fendo.2018.00608
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fendo.2018.00608/pdf
    Citation Count: 17
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