7601 - 7650 of 8587 Results
Title
Year
- FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors2023OPENTitle: FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptorsJournal Name: The EMBO JournalPublisher: Springer Science and Business Media LLCVol: 42Issue #: 13Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.15252/embj.2022112767Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.2022112767Citation Count: 52
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OPENTitle: PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systemsJournal Name: EMBO reportsPublisher: Springer Science and Business Media LLCVol: 24Issue #: 8Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.15252/embr.202256399Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embr.202256399Citation Count: 15
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OPENTitle: Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathyJournal Name: Translational NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40035-022-00309-xBest OA location URL: https://translationalneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s40035-022-00309-xCitation Count: 13
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OPENTitle: Genome-wide Analysis of Motor Progression in Parkinson DiseaseJournal Name: Neurology GeneticsPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 9Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1212/nxg.0000000000200092Best OA location URL: https://ng.neurology.org/content/nng/9/5/e200092.full.pdfCitation Count: 5
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RESTRICTEDTitle: Body Mass Index, Abdominal Adiposity, and Incidence of Parkinson Disease in French Women From the E3N Cohort StudyJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 100Issue #: 3Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000201468Citation Count: 9
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OPENTitle: PINK1: From Parkinson’s disease to mitophagy and back againJournal Name: PLOS BiologyPublisher: Public Library of Science (PLoS)Vol: 21Issue #: 6Start Page: e3002196End Page: e3002196Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1371/journal.pbio.3002196Best OA location URL: https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002196&type=printableCitation Count: 11
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OPENTitle: Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's diseaseJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 17Issue #: 5Start Page: 831End Page: 846Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1002/alz.12240Best OA location URL: https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12240Citation Count: 16
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OPENTitle: Distinct tau PET patterns in atrophy‐defined subtypes of Alzheimer's diseaseJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: 2Start Page: 335End Page: 344Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.jalz.2019.08.201Best OA location URL: https://escholarship.org/content/qt7k74z129/qt7k74z129.pdfCitation Count: 98
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OPENTitle: Genetic screening of a large series of North American sporadic and familial frontotemporal dementia casesJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: 1Start Page: 118End Page: 130Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/alz.12011Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7199807Citation Count: 63
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OPENTitle: Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer’s disease risk in humansJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: S2Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/alz.043533Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.043533Citation Count: 6
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OPENTitle: Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degenerationJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: 1Start Page: 91End Page: 105Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/alz.12001Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.12001Citation Count: 40
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OPENTitle: New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measuresJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: 1Start Page: 131End Page: 143Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jalz.2019.06.4956Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6949386Citation Count: 53
- Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration2019OPENTitle: Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degenerationJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: 1Start Page: 37End Page: 48Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.jalz.2019.04.007Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/j.jalz.2019.04.007Citation Count: 39
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OPENTitle: Cerebrovascular medin is associated with Alzheimer's disease and vascular dementiaJournal Name: Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringPublisher: WileyVol: 12Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/dad2.12072Best OA location URL: https://onlinelibrary.wiley.com/doi/pdf/10.1002/dad2.12072Citation Count: 20
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OPENTitle: Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes NeurotoxicJournal Name: Angewandte ChemiePublisher: WileyVol: 133Issue #: 17Start Page: 9299End Page: 9330Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1002/ange.202000451Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ange.202000451Citation Count: 12
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OPENTitle: Non‐coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in womenJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 17Issue #: 2Start Page: 215End Page: 225Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/alz.12181Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7920533Citation Count: 28
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OPENTitle: BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's DiseaseJournal Name: NeurotherapeuticsPublisher: Elsevier BVVol: 17Issue #: 4Start Page: 1785End Page: 1795Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1007/s13311-020-00965-9Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-020-00965-9.pdfCitation Count: 17
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OPENTitle: ASENT2020 Annual Meeting AbstractsJournal Name: NeurotherapeuticsPublisher: Springer Science and Business Media LLCVol: 17Issue #: 3Start Page: 1311End Page: 1323Publication Date:Open Access(OA) Status: OPENLicense: other-oaDOI - Digital Object Identifier: 10.1007/s13311-020-00896-5Best OA location URL: https://link.springer.com/content/pdf/10.1007/s13311-020-00896-5.pdfCitation Count: 0
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OPENTitle: Cognition in multiple system atrophy: a single‐center cohort studyJournal Name: Annals of Clinical and Translational NeurologyPublisher: WileyVol: 7Issue #: 2Start Page: 219End Page: 228Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/acn3.50987Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.50987Citation Count: 40
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OPENTitle: Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regionsJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41597-020-00642-8Best OA location URL: https://www.nature.com/articles/s41597-020-00642-8.pdfCitation Count: 320
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OPENTitle: Robot-Driven Locomotor Perturbations Reveal Synergy-Mediated, Context-Dependent Feedforward and Feedback Mechanisms of AdaptationJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-61231-8Best OA location URL: https://www.nature.com/articles/s41598-020-61231-8.pdfCitation Count: 25
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OPENTitle: Electrocardiographic changes predate Parkinson’s disease onsetJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-68241-6Best OA location URL: https://escholarship.org/content/qt4nf0d3rs/qt4nf0d3rs.pdfCitation Count: 21
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OPENTitle: Prediction of age at onset in Parkinson’s disease using objective specific neuroimaging genetics based on a sparse canonical correlation analysisJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-68301-xBest OA location URL: https://www.nature.com/articles/s41598-020-68301-x.pdfCitation Count: 11
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OPENTitle: Realistic simulation of virtual multi-scale, multi-modal patient trajectories using Bayesian networks and sparse auto-encodersJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-67398-4Best OA location URL: https://www.nature.com/articles/s41598-020-67398-4.pdfCitation Count: 10
- Serum BDNF levels correlate with regional cortical thickness in minor depression: a pilot study2020OPENTitle: Serum BDNF levels correlate with regional cortical thickness in minor depression: a pilot studyJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-71317-yBest OA location URL: https://www.nature.com/articles/s41598-020-71317-y.pdfCitation Count: 15
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OPENTitle: Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populationsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-74054-4Best OA location URL: https://www.nature.com/articles/s41598-020-74054-4.pdfCitation Count: 104
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OPENTitle: Clustering of Alzheimer’s and Parkinson’s disease based on genetic burden of shared molecular mechanismsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-76200-4Best OA location URL: https://publica.fraunhofer.de/handle/publica/264830Citation Count: 20
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OPENTitle: Reduced striatal vesicular monoamine transporter 2 in REM sleep behavior disorder: imaging prodromal parkinsonismJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-74495-xBest OA location URL: https://www.nature.com/articles/s41598-020-74495-x.pdfCitation Count: 15
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OPENTitle: Cerebrospinal fluid proteomics implicates the granin family in Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-59414-4Best OA location URL: https://www.nature.com/articles/s41598-020-59414-4.pdfCitation Count: 77
- Metabolic syndrome does not influence the phenotype of LRRK2 and GBA related Parkinson’s disease2020OPENTitle: Metabolic syndrome does not influence the phenotype of LRRK2 and GBA related Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-66319-9Best OA location URL: https://www.nature.com/articles/s41598-020-66319-9.pdfCitation Count: 21
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OPENTitle: Post-mortem ventricular cerebrospinal fluid cell-free-mtDNA in neurodegenerative diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-72190-5Best OA location URL: https://www.nature.com/articles/s41598-020-72190-5.pdfCitation Count: 22
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OPENTitle: Functionalization of amyloid fibrils via the Bri2 BRICHOS domainJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-78732-1Best OA location URL: https://www.nature.com/articles/s41598-020-78732-1.pdfCitation Count: 17
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OPENTitle: Association Between Cerebrospinal Fluid Biomarkers and Age-related Brain Changes in Patients with Normal Pressure HydrocephalusJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-66154-yBest OA location URL: https://www.nature.com/articles/s41598-020-66154-y.pdfCitation Count: 18
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OPENTitle: Constipation and sleep behaviour disorder associate with processing speed and attention in males with Parkinson’s disease over five years follow-upJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-020-75800-4Best OA location URL: https://www.nature.com/articles/s41598-020-75800-4.pdfCitation Count: 20
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RESTRICTEDTitle: Tremor-Dominant Cervical Dystonia: a Cerebellar SyndromeJournal Name: The CerebellumPublisher: Springer Science and Business Media LLCVol: 20Issue #: 2Start Page: 300End Page: 305Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s12311-020-01211-wCitation Count: 14
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RESTRICTEDTitle: Progressive Ataxia with Hemiplegic Migraines: a Phenotype of CACNA1A Missense Mutations, Not CAG Repeat ExpansionsJournal Name: The CerebellumPublisher: Springer Science and Business Media LLCVol: 20Issue #: 1Start Page: 134End Page: 139Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s12311-020-01185-9Citation Count: 8
- Impaired Saccade Adaptation in Tremor-Dominant Cervical Dystonia—Evidence for Maladaptive Cerebellum2020RESTRICTEDTitle: Impaired Saccade Adaptation in Tremor-Dominant Cervical Dystonia—Evidence for Maladaptive CerebellumJournal Name: The CerebellumPublisher: Springer Science and Business Media LLCVol: 20Issue #: 5Start Page: 678End Page: 686Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s12311-020-01104-yCitation Count: 16
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OPENTitle: CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriersJournal Name: Translational NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 9Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s40035-020-00192-4Best OA location URL: https://translationalneurodegeneration.biomedcentral.com/track/pdf/10.1186/s40035-020-00192-4Citation Count: 47
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OPENTitle: A blinded, controlled trial of objective measurement in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-020-00136-9Best OA location URL: https://www.nature.com/articles/s41531-020-00136-9.pdfCitation Count: 25
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OPENTitle: mHealth and wearable technology should replace motor diaries to track motor fluctuations in Parkinson’s diseaseJournal Name: npj Digital MedicinePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41746-019-0214-xBest OA location URL: https://www.nature.com/articles/s41746-019-0214-x.pdfCitation Count: 103
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OPENTitle: Enabling precision rehabilitation interventions using wearable sensors and machine learning to track motor recoveryJournal Name: npj Digital MedicinePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41746-020-00328-wBest OA location URL: https://www.nature.com/articles/s41746-020-00328-w.pdfCitation Count: 88
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OPENTitle: Exosome markers of LRRK2 kinase inhibitionJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-020-00138-7Best OA location URL: https://www.nature.com/articles/s41531-020-00138-7.pdfCitation Count: 19
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OPENTitle: Akinetic rigid symptoms are associated with decline in a cortical motor network in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-020-00120-3Best OA location URL: https://www.nature.com/articles/s41531-020-00120-3.pdfCitation Count: 28
- Long-term Parkinson’s disease quality of life after staged DBS: STN vs GPi and first vs second lead2020OPENTitle: Long-term Parkinson’s disease quality of life after staged DBS: STN vs GPi and first vs second leadJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-020-0115-3Best OA location URL: https://www.nature.com/articles/s41531-020-0115-3.pdfCitation Count: 24
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OPENTitle: Multivariate prediction of dementia in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-020-00121-2Best OA location URL: https://escholarship.org/content/qt5n39b8t8/qt5n39b8t8.pdfCitation Count: 41
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OPENTitle: Effect of data length on time delay and embedding dimension for calculating the Lyapunov exponent in walkingJournal Name: Journal of The Royal Society InterfacePublisher: The Royal SocietyVol: 17Issue #: 168Start Page: 20200311End Page: 20200311Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1098/rsif.2020.0311Best OA location URL: https://royalsocietypublishing.org/doi/pdf/10.1098/rsif.2020.0311Citation Count: 24
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OPENTitle: Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson DiseaseJournal Name: The Journal of ImmunologyPublisher: Oxford University Press (OUP)Vol: 205Issue #: 5Start Page: 1323End Page: 1330Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.4049/jimmunol.2000144Best OA location URL: https://www.jimmunol.org/content/jimmunol/205/5/1323.full.pdfCitation Count: 24
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RESTRICTEDTitle: When antibodies mislead: the quest for validationJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 585Issue #: 7824Start Page: 313End Page: 314Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1038/d41586-020-02549-1Citation Count: 37
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OPENTitle: Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophyJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 578Issue #: 7794Start Page: 273End Page: 277Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41586-020-1984-7Citation Count: 656
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OPENTitle: All that’s fit to preprintJournal Name: Nature BiotechnologyPublisher: Springer Science and Business Media LLCVol: 38Issue #: 5Start Page: 507End Page: 507Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41587-020-0536-xBest OA location URL: https://www.nature.com/articles/s41587-020-0536-x.pdfCitation Count: 11