1351 - 1400 of 8666 Results
Title
Year
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RESTRICTEDTitle: Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potentialJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 97Issue #:Start Page: 90End Page: 102Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2016.07.009Citation Count: 149
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RESTRICTEDTitle: Serotonin transporter in Parkinson's disease: A meta‐analysis of positron emission tomography studiesJournal Name: Annals of NeurologyPublisher: WileyVol: 81Issue #: 2Start Page: 171End Page: 180Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/ana.24859Best OA location URL: https://kclpure.kcl.ac.uk/portal/files/62952075/Serontin_Transporter_in_Parkinson_s_disease_SERT_Accepted_GREEN_AAM.pdfCitation Count: 79
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RESTRICTEDTitle: Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe SynthesisJournal Name: Journal of Medicinal ChemistryPublisher: American Chemical Society (ACS)Vol: 61Issue #: 16Start Page: 6945End Page: 6963Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1021/acs.jmedchem.7b01561Citation Count: 116
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RESTRICTEDTitle: Multicellular hypothesis for the pathogenesis of Alzheimer's diseaseJournal Name: The FASEB JournalPublisher: WileyVol: 31Issue #: 5Start Page: 1792End Page: 1795Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1096/fj.201601221rCitation Count: 19
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RESTRICTEDTitle: Understanding the Links Between Cardiovascular Disease and Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 35Issue #: 1Start Page: 55End Page: 74Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27836Best OA location URL: https://europepmc.org/articles/pmc6981000?pdf=renderCitation Count: 83
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RESTRICTEDTitle: Magnetic resonance imaging as a potential biomarker for Parkinson's diseaseJournal Name: Translational ResearchPublisher: Elsevier BVVol: 175Issue #:Start Page: 4End Page: 16Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.trsl.2015.12.006Citation Count: 23
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OPENTitle: Transcription Factor-Induced Lineage Selection of Stem-Cell-Derived Neural Progenitor CellsJournal Name: Cell Stem CellPublisher: Elsevier BVVol: 8Issue #: 6Start Page: 663End Page: 675Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.stem.2011.04.001Best OA location URL: http://www.cell.com/article/S1934590911001664/pdfCitation Count: 86
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RESTRICTEDTitle: Parkinson’s Disease and the COVID-19 PandemicJournal Name: Journal of Parkinson's DiseasePublisher: IOS PressVol: 11Issue #: 2Start Page: 431End Page: 444Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-202320Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd202320?id=journal-of-parkinsons-disease%2Fjpd202320Citation Count: 73
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RESTRICTEDTitle: Regulation of the Neurodegenerative Process Associated to Parkinson’s Disease by CD4+ T-cellsJournal Name: Journal of Neuroimmune PharmacologyPublisher: Springer Science and Business Media LLCVol: 10Issue #: 4Start Page: 561End Page: 575Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s11481-015-9618-9Citation Count: 52
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RESTRICTEDTitle: Animal models of l‐dopa‐induced dyskinesia in Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 33Issue #: 6Start Page: 889End Page: 899Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27337Citation Count: 71
- The Coronavirus Disease 2019 Crisis as Catalyst for Telemedicine for Chronic Neurological Disorders2020RESTRICTEDTitle: The Coronavirus Disease 2019 Crisis as Catalyst for Telemedicine for Chronic Neurological DisordersJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 77Issue #: 8Start Page: 927End Page: 927Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2020.1452Best OA location URL: https://repository.ubn.ru.nl//bitstream/handle/2066/226023/226023.pdfCitation Count: 183
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RESTRICTEDTitle: Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and EuropeansJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 77Issue #: 6Start Page: 746End Page: 746Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2020.0428Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2764340/jamaneurology_foo_2020_oi_200012.pdfCitation Count: 153
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RESTRICTEDTitle: Time for a New Image of Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 77Issue #: 11Start Page: 1345End Page: 1345Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2020.2412Citation Count: 29
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RESTRICTEDTitle: Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources PanelJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 78Issue #: 1Start Page: 102End Page: 102Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2020.3536Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573798Citation Count: 150
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RESTRICTEDTitle: Emerging Neuroimaging Biomarkers Across Disease Stage in Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 78Issue #: 10Start Page: 1262End Page: 1262Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2021.1312Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9017381Citation Count: 75
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RESTRICTEDTitle: Burden of Neurological Disorders Across the US From 1990-2017Journal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 78Issue #: 2Start Page: 165End Page: 165Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.1001/jamaneurol.2020.4152Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2772579/jamaneurology_feigin_2020_oi_200081_1612851425.16285.pdfCitation Count: 314
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RESTRICTEDTitle: Fovea and foveation in Parkinson's disease.Journal Name: Behavioral NeurosciencePublisher: American Psychological Association (APA)Vol: 127Issue #: 2Start Page: 139End Page: 150Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1037/a0031225Citation Count: 22
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RESTRICTEDTitle: Post-stroke Movement Disorders: The Clinical, Neuroanatomic, and Demographic Portrait of 284 Published CasesJournal Name: Journal of Stroke and Cerebrovascular DiseasesPublisher: Elsevier BVVol: 27Issue #: 9Start Page: 2388End Page: 2397Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.jstrokecerebrovasdis.2018.04.028Best OA location URL: https://zenodo.org/records/3873438/files/Proof_from_JSCVD-D-18-00257R1.pdfCitation Count: 65
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RESTRICTEDTitle: Meta-analysis of amantadine efficacy for improving preclinical research reliabilityJournal Name: Movement DisordersPublisher: WileyVol: 33Issue #: 10Start Page: 1555End Page: 1557Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27486Citation Count: 7
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RESTRICTEDTitle: Low Vitamin B12 and Parkinson DiseaseJournal Name: Mayo Clinic ProceedingsPublisher: Elsevier BVVol: 94Issue #: 5Start Page: 757End Page: 762Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.mayocp.2019.01.039Best OA location URL: http://www.mayoclinicproceedings.org/article/S0025619619301776/pdfCitation Count: 18
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OPENTitle: An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer’s DiseaseJournal Name: Journal of Alzheimer’s DiseasePublisher: SAGE PublicationsVol: 98Issue #: 3Start Page: 1053End Page: 1067Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jad-231075Citation Count: 2
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OPENTitle: The IkappaB Kinase Family Phosphorylates the Parkinson’s Disease Kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor SignalingJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 7Issue #: 6Start Page: e39132End Page: e39132Publication Date:Open Access(OA) Status: OPENLicense: cc0DOI - Digital Object Identifier: 10.1371/journal.pone.0039132Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039132&type=printableCitation Count: 205
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OPENTitle: Generation of human midbrain organoids from induced pluripotent stem cellsJournal Name: MNI Open ResearchPublisher: F1000 Research LtdVol: 3Issue #:Start Page: 1End Page: 1Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.12688/mniopenres.12816.1Best OA location URL: https://mniopenresearch.org/articles/3-1/v1/pdfCitation Count: 12
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OPENTitle: Decision making in frontotemporal dementia: neuropsychological and neuroimaging assessmentsJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 19Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2025.1632054Best OA location URL: https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1632054/pdfCitation Count: 0
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OPENTitle: Tackling a disease on a global scale, the Global Parkinson’s Genetics Program, GP2: A new generation of opportunitiesJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 112Issue #: 9Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.ajhg.2025.07.014Best OA location URL: https://www.cell.com/ajhg/pdf/S0002-9297(25)00284-8.pdfCitation Count: 0
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OPENTitle: Harmonization of CSF and imaging biomarkers in Alzheimer's disease: Need and practical applications for genetics studies and preclinical classificationJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 190Issue #:Start Page: 106373End Page: 106373Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nbd.2023.106373Best OA location URL: https://doi.org/10.1016/j.nbd.2023.106373Citation Count: 13
- Single-cell transcriptomics for immune profiling of cerebrospinal fluid in neurological diseases2025OPENTitle: Single-cell transcriptomics for immune profiling of cerebrospinal fluid in neurological diseasesJournal Name: Frontiers in ImmunologyPublisher: Frontiers Media SAVol: 16Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fimmu.2025.1599303Best OA location URL: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1599303/pdfCitation Count: 0
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OPENTitle: The neuro-toxin MPTP does not prevent reproduction in marmosetsJournal Name: MNI Open ResearchPublisher: F1000 Research LtdVol: 3Issue #:Start Page: 2End Page: 2Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.12688/mniopenres.12818.1Best OA location URL: https://mniopenresearch.org/articles/3-2/v1/pdfCitation Count: 0
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OPENTitle: An unusual presentation of Huntington’s disease-like syndrome in a patient with Xeroderma pigmentosum type F: Case report and review of the literatureJournal Name: Clinical Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 12Issue #:Start Page: 100340End Page: 100340Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.prdoa.2025.100340Best OA location URL: https://doi.org/10.1016/j.prdoa.2025.100340Citation Count: 0
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OPENTitle: a-synuclein PET Imaging: From Clinical Utility in Multiple System Atrophy to the Possible Diagnosis of Parkinson’s DiseaseJournal Name: CellsPublisher: MDPI AGVol: 14Issue #: 11Start Page: 834End Page: 834Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/cells14110834Best OA location URL: https://www.mdpi.com/2073-4409/14/11/834/pdf?version=1748956205Citation Count: 0
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OPENTitle: Increasing the use of mobile technology–derived endpoints in clinical trialsJournal Name: Clinical TrialsPublisher: SAGE PublicationsVol: 15Issue #: 3Start Page: 313End Page: 315Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1177/1740774518755393Best OA location URL: https://doi.org/10.1177/1740774518755393Citation Count: 23
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OPENTitle: Higher Frequency of Certain Cancers inLRRK2G2019S Mutation Carriers With Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 72Issue #: 1Start Page: 58End Page: 58Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2014.1973Best OA location URL: http://doi.org/10.1001/jamaneurol.2014.1973Citation Count: 91
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OPENTitle: Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body diseaseJournal Name: AutophagyPublisher: Informa UK LimitedVol: 14Issue #: 8Start Page: 1404End Page: 1418Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/15548627.2018.1461294Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15548627.2018.1461294?needAccess=trueCitation Count: 121
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OPENTitle: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/srep01393Best OA location URL: https://www.nature.com/articles/srep01393.pdfCitation Count: 150
- Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo2014OPENTitle: Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivoJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 137Issue #: 5Start Page: 1496End Page: 1513Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awu057Best OA location URL: https://academic.oup.com/brain/article-pdf/137/5/1496/11140606/awu057.pdfCitation Count: 220
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OPENTitle: GFAP mutations, age at onset, and clinical subtypes in Alexander diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 77Issue #: 13Start Page: 1287End Page: 1294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182309f72Best OA location URL: https://n.neurology.org/content/neurology/77/13/1287.full.pdfCitation Count: 230
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OPENTitle: Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 VectorsJournal Name: Molecular TherapyPublisher: Elsevier BVVol: 18Issue #: 8Start Page: 1490End Page: 1495Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/mt.2010.114Best OA location URL: http://www.cell.com/article/S1525001616310991/pdfCitation Count: 80
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OPENTitle: Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative diseaseJournal Name: Journal of Comparative NeurologyPublisher: WileyVol: 515Issue #: 3Start Page: 269End Page: 294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/cne.22040Best OA location URL: http://doi.org/10.1002/cne.22040Citation Count: 55
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OPENTitle: LRRK2 levels in immune cells are increased in Parkinson’s diseaseJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-017-0010-8Best OA location URL: https://doi.org/10.1038/s41531-017-0010-8Citation Count: 237
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OPENTitle: Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagyJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41467-017-01609-xBest OA location URL: https://doi.org/10.1038/s41467-017-01609-xCitation Count: 125
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OPENTitle: Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 104Issue #: 47Start Page: 18754End Page: 18759Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0704908104Best OA location URL: http://doi.org/10.1073/pnas.0704908104Citation Count: 416
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OPENTitle: Altered Pharyngeal Muscles in Parkinson DiseaseJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 71Issue #: 6Start Page: 520End Page: 530Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0b013e318258381bBest OA location URL: https://academic.oup.com/jnen/article-pdf/71/6/520/9562114/71-6-520.pdfCitation Count: 136
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OPENTitle: GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark miceJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-018-23795-4Best OA location URL: https://www.nature.com/articles/s41598-018-23795-4.pdfCitation Count: 39
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OPENTitle: Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimer’s disease pathologiesJournal Name: Journal of NeurochemistryPublisher: WileyVol: 109Issue #: 2Start Page: 623End Page: 630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2009.05996.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1471-4159.2009.05996.xCitation Count: 140
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OPENTitle: In vitro high affinity α‐synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain1Journal Name: Journal of NeurochemistryPublisher: WileyVol: 105Issue #: 4Start Page: 1428End Page: 1437Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2008.05245.xBest OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1471-4159.2008.05245.xCitation Count: 92
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OPENTitle: Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's diseaseJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 42Issue #: 9Start Page: 781End Page: 785Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ng.642Best OA location URL: http://hdl.handle.net/20.500.11820/b0e35720-bc0d-43af-818b-6597947a050fCitation Count: 754
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OPENTitle: Noninvasive optical inhibition with a red-shifted microbial rhodopsinJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 17Issue #: 8Start Page: 1123End Page: 1129Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nn.3752Best OA location URL: http://hdl.handle.net/1721.1/98648Citation Count: 542
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OPENTitle: Randomized Clinical Trial of 3 Types of Physical Exercise for Patients With Parkinson DiseaseJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 70Issue #: 2Start Page: 183End Page: 183Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2013.646Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4574905Citation Count: 386
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OPENTitle: Interocular Asymmetry of Foveal Thickness in Parkinson DiseaseJournal Name: Journal of OphthalmologyPublisher: WileyVol: 2012Issue #:Start Page: 1End Page: 6Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1155/2012/728457Best OA location URL: https://downloads.hindawi.com/journals/joph/2012/728457.pdfCitation Count: 74
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OPENTitle: Comparison of the ligand binding site of CYP2C8 with CYP26A1 and CYP26B1: a structural basis for the identification of new inhibitors of the retinoic acid hydroxylasesJournal Name: Journal of Enzyme Inhibition and Medicinal ChemistryPublisher: Informa UK LimitedVol: 31Issue #: sup2Start Page: 148End Page: 161Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1080/14756366.2016.1193734Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/14756366.2016.1193734?needAccess=trueCitation Count: 12