1701 - 1750 of 8808 Results
Title
Year
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OPENTitle: Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodentsJournal Name: Journal of Comparative NeurologyPublisher: WileyVol: 522Issue #: 11Start Page: 2465End Page: 2480Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/cne.23583Best OA location URL: http://doi.org/10.1002/cne.23583Citation Count: 127
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OPENTitle: Anatomy of graft-induced dyskinesias: Circuit remodeling in the parkinsonian striatumJournal Name: Basal GangliaPublisher: Elsevier BVVol: 2Issue #: 1Start Page: 15End Page: 30Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.baga.2012.01.002Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3375918Citation Count: 13
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OPENTitle: Parkinson's disease, cortical dysfunction, and alpha‐synucleinJournal Name: Movement DisordersPublisher: WileyVol: 26Issue #: 8Start Page: 1436End Page: 1442Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.23697Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3154995Citation Count: 23
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OPENTitle: A Role for Neuronal Alpha-Synuclein in Gastrointestinal ImmunityJournal Name: Journal of Innate ImmunityPublisher: S. Karger AGVol: 9Issue #: 5Start Page: 456End Page: 463Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000477990Best OA location URL: https://www.karger.com/Article/Pdf/477990Citation Count: 252
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OPENTitle: Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cellsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41598-017-10501-zBest OA location URL: https://www.nature.com/articles/s41598-017-10501-z.pdfCitation Count: 97
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OPENTitle: Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brainJournal Name: Journal of NeurochemistryPublisher: WileyVol: 135Issue #: 6Start Page: 1242End Page: 1256Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1111/jnc.13369Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.13369Citation Count: 66
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OPENTitle: MKK6 binds and regulates expression of Parkinson’s disease‐related protein LRRK2Journal Name: Journal of NeurochemistryPublisher: WileyVol: 112Issue #: 6Start Page: 1593End Page: 1604Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1471-4159.2010.06568.xBest OA location URL: http://doi.org/10.1111/j.1471-4159.2010.06568.xCitation Count: 100
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OPENTitle: Association of Parkinson Disease with Structural and Regulatory Variants in the HLA RegionJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 93Issue #: 5Start Page: 984End Page: 993Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.ajhg.2013.10.009Best OA location URL: http://www.cell.com/article/S0002929713004667/pdfCitation Count: 167
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OPENTitle: Lentiviral Overexpression of GRK6 Alleviates l -Dopa–Induced Dyskinesia in Experimental Parkinson’s DiseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 2Issue #: 28Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.3000664Best OA location URL: http://doi.org/10.1126/scitranslmed.3000664Citation Count: 135
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OPENTitle: Ser(P)‐1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 10Start Page: 1543End Page: 1550Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26686Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5053851Citation Count: 181
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OPENTitle: Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degenerationJournal Name: Experimental NeurologyPublisher: Elsevier BVVol: 228Issue #: 1Start Page: 118End Page: 125Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.12.018Citation Count: 75
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OPENTitle: Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosisJournal Name: Annals of NeurologyPublisher: WileyVol: 64Issue #: 1Start Page: 60End Page: 70Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.21425Best OA location URL: http://doi.org/10.1002/ana.21425Citation Count: 719
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OPENTitle: Dopamine D3 receptor selective ligands with varying intrinsic efficacies at adenylyl cyclase inhibition and mitogenic signaling pathwaysJournal Name: SynapsePublisher: WileyVol: 64Issue #: 3Start Page: 251End Page: 266Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/syn.20725Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3821045Citation Count: 21
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OPENTitle: Conditional transgenic mice expressing C-terminally truncated human α-synuclein (αSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neuronsJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1750-1326-4-34Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/1750-1326-4-34Citation Count: 90
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OPENTitle: Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patientsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep30793Best OA location URL: https://www.nature.com/articles/srep30793.pdfCitation Count: 34
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OPENTitle: A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusionsJournal Name: Molecular and Cellular NeurosciencePublisher: Elsevier BVVol: 46Issue #: 3Start Page: 597End Page: 606Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.mcn.2010.12.011Citation Count: 72
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OPENTitle: Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutationsJournal Name: Movement DisordersPublisher: WileyVol: 28Issue #: 14Start Page: 1966End Page: 1971Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25647Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3859844Citation Count: 136
- α-Synuclein Gene May Interact with Environmental Factors in Increasing Risk of Parkinson’s Disease2010OPENTitle: α-Synuclein Gene May Interact with Environmental Factors in Increasing Risk of Parkinson’s DiseaseJournal Name: NeuroepidemiologyPublisher: S. Karger AGVol: 35Issue #: 3Start Page: 191End Page: 195Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1159/000315157Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2945263Citation Count: 62
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OPENTitle: Abrogation of α-synuclein–mediated dopaminergic neurodegeneration in LRRK2-deficient ratsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 25Start Page: 9289End Page: 9294Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1403215111Best OA location URL: https://www.pnas.org/content/pnas/111/25/9289.full.pdfCitation Count: 206
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OPENTitle: Impact of dendritic spine preservation in medium spiny neurons on dopamine graft efficacy and the expression of dyskinesias in parkinsonian ratsJournal Name: European Journal of NeurosciencePublisher: WileyVol: 31Issue #: 3Start Page: 478End Page: 490Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1460-9568.2010.07077.xBest OA location URL: http://doi.org/10.1111/j.1460-9568.2010.07077.xCitation Count: 63
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OPENTitle: Brain biochemistry in autopsied patients with essential tremorJournal Name: Movement DisordersPublisher: WileyVol: 27Issue #: 1Start Page: 113End Page: 117Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.24004Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3261329Citation Count: 55
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OPENTitle: Genetic modification of the association of paraquat and Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 27Issue #: 13Start Page: 1652End Page: 1658Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25216Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3572192Citation Count: 90
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OPENTitle: Serotonin transporter inhibition attenuatesl‐DOPA‐induced dyskinesia without compromisingl‐DOPA efficacy in hemi‐parkinsonian ratsJournal Name: European Journal of NeurosciencePublisher: WileyVol: 36Issue #: 6Start Page: 2839End Page: 2848Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/j.1460-9568.2012.08202.xCitation Count: 72
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OPENTitle: SIRT2 as a Therapeutic Target for Age-Related DisordersJournal Name: Frontiers in PharmacologyPublisher: Frontiers Media SAVol: 3Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fphar.2012.00082Best OA location URL: https://www.frontiersin.org/articles/10.3389/fphar.2012.00082/pdfCitation Count: 132
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OPENTitle: ER proteostasis disturbances in Parkinson's disease: novel insightsJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2015.00039Best OA location URL: https://doi.org/10.3389/fnagi.2015.00039Citation Count: 31
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OPENTitle: Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of AgingJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 84Issue #: 14Start Page: 1433End Page: 1442Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0000000000001437Best OA location URL: https://n.neurology.org/content/neurology/84/14/1433.full.pdfCitation Count: 128
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OPENTitle: Ade novocompound targeting α-synuclein improves deficits in models of Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 139Issue #: 12Start Page: 3217End Page: 3236Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/aww238Best OA location URL: https://academic.oup.com/brain/article-pdf/139/12/3217/24173157/aww238.pdfCitation Count: 137
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OPENTitle: Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of AβviaexosomesJournal Name: The FASEB JournalPublisher: WileyVol: 33Issue #: 3Start Page: 3758End Page: 3771Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1096/fj.201801319rCitation Count: 41
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OPENTitle: Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2Journal Name: International Journal of Molecular SciencesPublisher: MDPI AGVol: 13Issue #: 8Start Page: 10022End Page: 10040Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/ijms130810022Best OA location URL: https://www.mdpi.com/1422-0067/13/8/10022/pdf?version=1403144658Citation Count: 25
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OPENTitle: Nucleus Basalis of Meynert Stimulation for Dementia: Theoretical and Technical ConsiderationsJournal Name: Frontiers in NeurosciencePublisher: Frontiers Media SAVol: 12Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnins.2018.00614Best OA location URL: https://doi.org/10.3389/fnins.2018.00614Citation Count: 33
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OPENTitle: Nicotinic Acetylcholine Receptor Density in Cognitively Intact Subjects at an Early Stage of Parkinson’s DiseaseJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 6Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2014.00213Best OA location URL: https://doi.org/10.3389/fnagi.2014.00213Citation Count: 26
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OPENTitle: Association of Parkinson disease age of onset with DRD2, DRD3 and GRIN2B polymorphismsJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 22Issue #:Start Page: 102End Page: 105Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2015.11.016Best OA location URL: http://doi.org/10.1016/j.parkreldis.2015.11.016Citation Count: 18
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OPENTitle: Parkin Mutations Reduce the Complexity of Neuronal Processes in iPSC-Derived Human NeuronsJournal Name: Stem CellsPublisher: Oxford University Press (OUP)Vol: 33Issue #: 1Start Page: 68End Page: 78Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/stem.1854Best OA location URL: https://academic.oup.com/stmcls/article-pdf/33/1/68/42014165/stmcls_33_1_68.pdfCitation Count: 101
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OPENTitle: Peripheral Biomarkers of Parkinson’s Disease Progression and Pioglitazone EffectsJournal Name: Journal of Parkinson's DiseasePublisher: SAGE PublicationsVol: 5Issue #: 4Start Page: 731End Page: 736Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.3233/jpd-150666Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5061495Citation Count: 29
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OPENTitle: Olfactory dysfunction in Parkinson's disease: Positive effect of cigarette smokingJournal Name: Movement DisordersPublisher: WileyVol: 30Issue #: 6Start Page: 859End Page: 862Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26126Best OA location URL: http://doi.org/10.1002/mds.26126Citation Count: 34
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OPENTitle: Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophyJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-015-0008-9Best OA location URL: https://escholarship.org/uc/item/4bm3c0n8Citation Count: 142
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OPENTitle: Genetic analysis of α‐synuclein 3′ untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodiesJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 13Issue #: 11Start Page: 1237End Page: 1250Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.jalz.2017.03.001Citation Count: 29
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OPENTitle: Therapeutic cloning in individual parkinsonian miceJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 14Issue #: 4Start Page: 379End Page: 381Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nm1732Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2786166Citation Count: 116
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OPENTitle: Computational analysis of the LRRK2 interactomeJournal Name: PeerJPublisher: PeerJVol: 3Issue #:Start Page: e778End Page: e778Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.7717/peerj.778Best OA location URL: https://doi.org/10.7717/peerj.778Citation Count: 56
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OPENTitle: Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGEJournal Name: BMC BioinformaticsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2105-7-475Best OA location URL: https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-475Citation Count: 38
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OPENTitle: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?Journal Name: Rambam Maimonides Medical JournalPublisher: Rambam Health CorporationVol: 1Issue #: 2Start Page: e0011End Page: e0011Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.5041/rmmj.10011Best OA location URL: https://doi.org/10.5041/rmmj.10011Citation Count: 8
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OPENTitle: Effect of Deep Brain Stimulation on Parkinson's Nonmotor Symptoms following Unilateral DBS: A Pilot StudyJournal Name: Parkinson's DiseasePublisher: WileyVol: 2011Issue #:Start Page: 1End Page: 4Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.4061/2011/507416Best OA location URL: https://downloads.hindawi.com/journals/pd/2011/507416.pdfCitation Count: 29
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OPENTitle: Discovery and characterization of a novel series of N -phenylsulfonyl-1 H -pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu 4 )Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4955388Citation Count: 5
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OPENTitle: The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2Journal Name: Biochemical JournalPublisher: Portland Press Ltd.Vol: 474Issue #: 9Start Page: 1547End Page: 1558Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1042/bcj20160909Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6178381Citation Count: 35
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OPENTitle: DJ-1 Interacts with and Regulates Paraoxonase-2, an Enzyme Critical for Neuronal Survival in Response to Oxidative StressJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 9Start Page: e106601End Page: e106601Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0106601Best OA location URL: https://escholarship.org/uc/item/6g52h4gcCitation Count: 46
- Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration2012OPENTitle: Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegenerationJournal Name: Journal of Clinical InvestigationPublisher: American Society for Clinical InvestigationVol: 122Issue #: 9Start Page: 3159End Page: 3169Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1172/jci64575Citation Count: 57
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OPENTitle: Select E2 enzymes differentially regulate parkin activation and mitophagyJournal Name: Journal of Cell SciencePublisher: The Company of BiologistsVol:Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1242/jcs.147520Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4132391Citation Count: 69
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OPENTitle: Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep40263Best OA location URL: https://www.nature.com/articles/srep40263.pdfCitation Count: 55
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OPENTitle: LRRK2 interactions with α-synuclein in Parkinson’s disease brains and in cell modelsJournal Name: Journal of Molecular MedicinePublisher: Springer Science and Business Media LLCVol: 91Issue #: 4Start Page: 513End Page: 522Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00109-012-0984-yBest OA location URL: https://link.springer.com/content/pdf/10.1007/s00109-012-0984-y.pdfCitation Count: 74
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OPENTitle: Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 115Issue #: 22Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1718946115Best OA location URL: https://www.pnas.org/content/pnas/115/22/E5164.full.pdfCitation Count: 109