… including the thymus and spleen, which are major immune system organs for B and T lymphocyte maturation and … has also been described in different cells of the immune system, including B lymphocytes. The presence of … to the neurodegenerative process and/or the secondary systemic manifestations of the disease. Anticipated Outcome: …

… that produces progressive degeneration of the dopamine system, we will perform a dose-finding and timing study … drug, venlafaxine, for the capacity to protect the dopamine system during the process of degeneration. Analyses will use … in a model of severe, sudden damage to the dopamine system. January 2014 …

… However, LRRK2 is abundantly expressed in the immune system, offering a unique opportunity to study the pathological connections between the immune and nervous systems. Objectives for Supplemental Investigation: We have … by which LRRK2 is induced by interferon-gamma (an immune system drug) in macrophages (immune cells). In tight …

… within her research is the application of remote monitoring systems in Parkinson’s patients to promote person-centered … and to generate input for clinical decision support systems. …

… within her research is the application of remote monitoring systems in individuals with Parkinson’s disease to promote … and to generate input for clinical decision support systems. …

… studying the relationships between the peripheral immune system and the central nervous system and utilizing these relationships to better …