… production techniques, vendor management and inventory systems. This is a hybrid-flex position that will require … internal needs Introduce and manage an easy-to-use ordering system for internal stakeholders to request materials, … Excellent project management skills, capable of handling multiple projects, coordinating with cross-functional teams …

… Objective/Rationale: Multiple evidence supports the notion that a malfunction of the ubiquitin-proteasome system and autophagy plays a crucial role in protein …

… humans and in research models support a role for the immune system in the progression of Parkinson's disease. Local … bring understanding to how the peripheral adaptive immune system (T cells) interacts with the brain resident immune system (microglia), and that this knowledge will permit us …

… handful of candidate enzymes in a lower organism worm based system. These gains will now be channeled into a rodent … In other words, hits from a high throughput screening system in worms will now be applied in a rational manner to … and dopamine neuron loss. The chosen factors will be systematically tested in rats to block dopamine …

… and fewer and fewer dopamine terminals survive, another system kicks in: the seratonin neurons. The serotonin … dopamine in a physiological manner. The seratonin system is known to be affected in PD, but the extent of … innervation in the synthesis and release of dopamine from systemically administered levodopa and in the development of …

… and cellular studies. This project will investigate multiple dose levels of NPT001 on disaggregation and … play a role in PD. This project investigated the effects of multiple dose levels of NPT001 on neuropathology and motor …