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Region-specific Effects of Pathology and Vocal Training
… We hypothesize that pathology in the cranial sensorimotor system specifically results in early vocalization deficits … specifically target pathology in the cranial sensorimotor system and should serve as an early therapeutic option in …
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Macrophage Precursors as Biomarker for LRRK2-associated Parkinson disease
… contribute to the development of Parkinson Disease, a multisystem disorder. Neuronal loss is a prerequisite to develop … disease and a crosstalk between the brain and the immune system has been postulated. Assuming that immune cells are … processes based on a constant crosstalk between the immune system and the brain. We expect that the assay will as well …
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Uncovering the Promise of c-Abl as a Therapeutic Target: Testing Available Treatments and Supporting New Therapies
March 15, 2017
… in the field and explain why we’re strategically funding multiple research projects around the same target to help … or read a blog post for more on c-Abl and nilotinib. Multiple Trials Give More Data to Draw and Compare … different sites with diverse study designs. The benefit of multiple trials is that researchers will be armed with more …
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mTORC1 as a Target for the Treatment of Levodopa-induced Dyskinesia
… the advantage of reducing potential side-effects exerted by systemic inhibition of mTORC1. In addition, the selective … Raptor in intact mice. We tested two protocols based on multiple (2 to 5) stereotaxic injections of increasing …
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The Michael J. Fox Foundation Launches The Edmond J. Safra Fellowship in Movement Disorders
December 2, 2014
… Disorders Center at the University of Pennsylvania Health System and president of the International Parkinson and … a year for two years. Fellowships will be granted to multiple centers in each round of funding. Interested …
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Parkinson’s Disease Economic Burden on Patients, Families and the Federal Government Is $52 Billion, Doubling Previous Estimates
June 13, 2019
… on patients, care partners, payers, employers, healthcare systems and government programs. For many years, the … Medicaid and Social Security.” To conduct this study, multiple data sources were used to fully understand and …