… alpha-synuclein and glucocerebrosidase in a range of cell systems including PD patient–derived cells. Furthermore, … drug discoverers through provision of a quantitative assay system which can been screened for new candidate drugs for …

… to find alternatives to the stimulation of the dopaminergic system through levodopa and dopamine agonists, as long-term … the glutamate receptor mGluR4, which bypasses the dopamine system, leads to functional improvement in pre-clinical …

… effectiveness as a PD treatment.   Study Design:  Using a system for growing bacteria, we will cultivate the L-dopa … viruses can trigger any systemic or local immune responses that could limit its …

… environment can affect the activity of the nervous system, and inflammation in the gut could contribute to the … individuals, with and without PD, collected as part of the Systemic Synuclein Sampling study (S4). Samples of colon …

… play in ambulation issues. Changes in the acetylcholine system have been implicated in Parkinson’s-associated … will focus their efforts on understanding the acetylcholine system in more detail, parsing out its effect on falls and …

… announced, too, that the drug gets into the central nervous system well and reduces levels of alpha-synuclein in blood … anti-alpha-synuclein antibody -- the body's natural immune system fighters -- is one way researchers aim to stop the …