… from 1974 to 2018 on 200+ pesticides. We will apply a systems biology approach with high-throughput data … “pesticide-wide association study” in PD followed by systems biology analysis of PD-related pesticides. Impact on …       This study will shed light on how biological systems operate and interact in response to pesticide …

… Study Rationale: Multiple candidate Parkinson’s disease (PD) biomarkers have … validated. Using a targeted mass spectrometry platform, a multiplexed assay (experimental set-up) will be developed to …

… degeneration of dopamine neurons in the central nervous system (CNS). It is now well established that PD lesions … to the biopsies of 10 control patients and 5 patients with multiple system atrophy (a parkinsonian syndrome which is a common …

… has been proposed that abnormalities in the enteric nervous system, a semi-independent network of nerves lining the … Project Description: We will examine the enteric nervous system in postmortem tissue samples from patients with PD … fluctuations), for modeling Parkinson’s in experimental systems (cells or animals), and for understanding the …

… circumstances is also crucial for building a support system that can help people living with Parkinson’s disease … they can also lead to new contacts and a broader support system. To learn more and start building your own support system, visit parkinsonsbuddynetwork.michaeljfox.org. Kat …