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Analysis of the Enteric Nervous System Using Routine Colonic Biopsies: A Biomarker of Neurodegeneration in Parkinson's Disease
… degeneration of dopamine neurons in the central nervous system (CNS). It is now well established that PD lesions … to the biopsies of 10 control patients and 5 patients with multiple system atrophy (a parkinsonian syndrome which is a common …
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Parkinson's Disease Biomarker Discovery and Verification Using Multiple Reaction Monitoring
… Study Rationale: Multiple candidate Parkinson’s disease (PD) biomarkers have … validated. Using a targeted mass spectrometry platform, a multiplexed assay (experimental set-up) will be developed to …
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Evaluation of the Enteric Nervous System in PD
… has been proposed that abnormalities in the enteric nervous system, a semi-independent network of nerves lining the … Project Description: We will examine the enteric nervous system in postmortem tissue samples from patients with PD … fluctuations), for modeling Parkinson’s in experimental systems (cells or animals), and for understanding the …
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The Power of Connections: Creating a Support System Online
June 1, 2021
… circumstances is also crucial for building a support system that can help people living with Parkinson’s disease … they can also lead to new contacts and a broader support system. To learn more and start building your own support system, visit parkinsonsbuddynetwork.michaeljfox.org. Kat …
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In Vivo Distribution of α-Synuclein In Multiple Tissues and Biofluids in Parkinson’s Disease
September 1, 2020
… Objective: The Systemic Synuclein Sampling Study (S4) measured α-synuclein in multiple tissues and biofluids within the same patients with …