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Arjun Balachandar, MD
… such as using machine learning to develop tools to detect sleep from deep brain activity in deep brain stimulation … undertreated facets of Parkinson’s disease such as gait and sleep disorders and using new neural recording technology …
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PPMI Dispatch: More Sites Recruiting While Scientists Uncover New Ways to Predict Parkinson’s
March 25, 2021
… data analysis. Brain Scan May Predict Parkinson’s after Sleep Disorder A dopamine activity scan may help predict Parkinson’s in a high-risk group with REM sleep behavior disorder or RBD (physically acting out dreams …
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What We Fund: $21 Million to Ease Symptoms, Profile Genes and Test for the “Parkinson’s Scent"
August 30, 2021
… a drug in pre-clinical models that may help people with PD sleep better . The drug targets a protein that plays a role … body’s biological clock. The team will also study if better sleep helps protect cells from other changes seen in PD such …
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Recruitment is on for PPMI's New Pre-Motor Cohort
June 5, 2013
… PD: reduced sense of smell (hyposmia); rapid eye movement sleep behavior disorder (RBD); and a mutation in the LRRK2 … smell survey RBD: Many people with Parkinson’s have trouble sleeping. One particular sleep disorder that is associated …
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What Might Early Parkinson’s Look Like?
March 18, 2015
… Institute at Weill Cornell Medical Center, said that REM sleep behavior disorder, characterized by a tendency to act out one’s dreams while asleep, is one of the strongest prediagnostic symptoms, along … Markers Initiative study is observing people with REM sleep behavior disorder and smell loss — among other …
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Alpha-synuclein Effects on Gut-brain Circuits and Pre-motor Symptoms in Parkinson’s Disease
… affecting this spread, resulting in early symptoms such as sleep disorders seen in humans before development of … that may occur before the movement problems, particularly sleep disorders. Given the reduced risk of PD in women prior … alpha-synuclein pathology to prevent disease spread. Our sleep and menopause studies will further identify …