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SUPPLEMENT: Rescreening of the MJFF Compound Library to Identify Molecules that Can be Used to Monitor Alpha-synuclein
… sections taken from the brains of people with PD and with multiple system atrophy (MSA) using the tritium-labeled versions of BF3620 …
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PET Tracer to Support Trials of Drugs Inhibiting Neuroinflammation via the NLRP3 Inflammasome
… diseases such as Alzheimer’s, motor neuron disease, and multiple system atrophy. Next Steps for Development: Once the PET tracer has …
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Is Parkinson’s Disease a Low-grade Inflammatory Bowel Disease?
… and 6 patients with progressive supranuclear palsy and multiple system atrophy. Each PD patient had a neurological (disease …
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Using the Chemical Modification of Alpha-synuclein to Define Disease State and Facilitate Patient Stratification in Parkinson’s Disease
… to discriminate between PD, Dementia with Lewy body (DLB), Multiple system atrophy (MSA) and healthy controls, which will allow us to …
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Maximizing the Sensitivity of Seed Amplification Assays Used to Detect Alpha-synuclein Aggregates
… but distinguishable protein aggregates involved in PD and multiple systems atrophy (MSA). Impact on Diagnosis/Treatment of Parkinson’s …
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Episode 10: Understanding Genetics, Pathology, and Progression in Parkinson's Disease and Atypical Parkinsonian Syndromes with Huw Morris
March 5, 2024
… Syndromes, such as progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and dementia …