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Blood Test for Stratifying People with Parkinson’s Disease based on Extracellular Vesicles Derived from Neurons
… stratify different synucleinopathies, including PD, LBD and multiple system atrophy (MSA). Study Design: NeuroDex has already …
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Clinical Development of the PET Tracer Candidate MODAG-009 for quantitative Detection of Alpha-synuclein Pathology in Parkinson’s Disease
… Study Rationale: In both Parkinson's disease and multiple system atrophy (MSA), the protein alpha-synuclein becomes altered, …
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Multimodal MRI Markers for Parkinson's Disease
… MRI technology but is unique in that it utilizes multiple MRI modalities to measure brain changes in PD, … subjects with a diagnosis of PD, 15 subjects with multiple system atrophy, and 20 healthy subjects for comparison. Relevance …
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Improving the generalizability and robustness of MRI-derived biomarkers of Parkinson's Disease through analytical and data variability evaluations
… is that dissimilar MRI-based measurements of brain atrophy provided by different software tools or measured in … the existing literature and we will re-analyse them using multiple different software tools and multiple different data sets. We will then aggregate the …
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Anle138b Clinical Phase 1 Studies: Food Effect, Safety and Tolerability as well as Pharmacokinetics in Parkinson´s Disease Patients
… finalize ongoing plans for disease modification studies in multiple system atrophy (MSA) and Parkinson’s. …
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The Michael J. Fox Foundation and Prothena Partner to Accelerate Discovery of Novel Biomarkers for Parkinson’s Disease
May 4, 2015
… look forward to reporting results from our ongoing Phase 1 multiple ascending dose study of PRX002 in patients with … disease, dementia with Lewy bodies, and multiple system atrophy, which collectively are termed synucleinopathies. …