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Luca Scorrano, MD, PhD
… cristae membranes tight, deficient in dominant optic atrophy and targeted during apoptosis; (ii) identified the …
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Ruolan Liu, MD, PhD, MS
… neurological disorders, such as myasthenia gravis and multiple sclerosis. She was awarded with a Career … interest is to explore the interaction between the nervous system and immune system influencing the development and pathogenesis of …
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Effect of NPT088 in Alpha-synuclein Overexpressing Models
… Grant: NeuroPhage technology simultaneously targets multiple misfolded proteins (e.g., alpha-synuclein, … to the early lead candidate, NPT001. NPT088 can be dosed systemically, which provides a significant advantage over … project, a single, dose-level study of NPT088 followed by a multiple dose-level study will be conducted in …
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Michael J. Fox Foundation Honors Virginia Man-Yee Lee, PhD, with Robert A. Pritzker Prize for Leadership in Parkinson's Research
November 12, 2018
… that misfolded proteins are transmitted through the nervous system, contributing to Parkinson's and other … and the relationship of Parkinson's to diseases such as multiple system atrophy and Alzheimer's. She also is a partner in MJFF's …
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Michael J. Fox Foundation and Tau Consortium Announce Partnership to Develop New Imaging Tools for Devastating Neurodegenerative Diseases
October 24, 2017
… diseases -- Parkinson's disease, Lewy body dementia, multiple system atrophy, progressive supranuclear palsy and frontotemporal …
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What We Fund: $13.7M to Studies toward Measuring Mobility Outcomes and Profiling Genes in Parkinson’s
June 23, 2023
… itself to alpha-synuclein in pre-clinical models of PD and Multiple System Atrophy (MSA). The aim is to detect alpha-synuclein presence …