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Memory and Thinking Changes in Parkinson’s Disease
… and problem solving (executive function) examples: juggling multiple ongoing projects, figuring out solutions such as … might find it more challenging to concentrate or manage multiple tasks at once. As with all Parkinson’s symptoms, …
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Pharmacological PHD Inhibition as a Potential PD Neuroprotectant Therapy
… the potential involvement of PHDs in neurodegeneration in a system that emulates the chronic and multifactoral nature of …
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How Does GBA1 Dysfunction Influence Parkinson's Disease?
… We hope to learn whether our model will provide a good system in which to study the effects of GBA1 gene defects on …
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Validating the Electrocardiogram as a Tool to Identify Pre-motor Parkinson's Disease
… when the pathology is restricted to the peripheral nervous system and/or lower brain stem and thereby enhance the …
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Effect of Novel Neuronal Nicotinic Receptor Compounds on Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease
… neuronal nicotinic receptors (NNRs) in the central nervous system for their ability to reduce L-dopa-induced …
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Phenotypic Characterization of BAC LRRK2 Transgenic Pre-clinical Models
… tests. The integrity of the nigrostriatal dopamine system will be assessed by examination of striatal dopamine …
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