…  We hypothesize that specific changes in the immune system play a role in the development and progression of PD … from individuals with varying forms of PD. We will then use multiple single-cell analytic techniques to catalog the …

… (San Diego). Over his career Dr. Pinkerton has worked in multiple areas including CNS, virology, diabetes, … for in-licensing efforts and competitive intelligence for multiple targets, in addition to developing IP strategies around multiple chemical series. In addition to numerous …

… innovative drug targets to address unmet needs in multiple disorders. His work has been published in leading … Research Excellence Award. Dr. Vasudevan also teaches multiple courses in pharmacology for undergraduate … and MSc students. Dr. Vasudevan is a reviewer for multiple journals and granting agencies, and he consults for …

… visualize alpha-synuclein in living human patients with multiple system atrophy (a related parkinsonism). AC Immune is now advancing …

… cohorts, i.e. patients with diabetes mellitus type 2 and multiple sclerosis. For both conditions, ghrelin serum … potential. In addition, it is known that ghrelin acts on systems that frequently are also affected in PD … sleep, etc.). Proof of an early disturbance in the ghrelin system (evolving) PD might therefore be of future diagnostic …

… Rationale:  There is growing indication that the immune system plays a role in the development and progression of … the genes responsible for the regulation of the immune system, particularly HLA and KIR. The central element of … In some cases, the same variants show association with multiple traits, whereas in other cases, the associations …