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Team Big B: How Honoring Brian Adam Turned 100 Miles into Impact
December 22, 2025
… of Big B. I watched Brian battle Parkinson’s disease and Multiple System Atrophy for years, and he faced the disease and the daily …
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Development of Nanobodies as Novel Tools to Characterize LRRK2 as a Potential Drug Target for Parkinson's Disease
… (accelerates chemical reactions) functions. Targeting the multiple enzymatic functions of LRRK2 represents a very … fragments derived from a special type of antibodies (immune system cells) present in camelids such as llamas. In recent …
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Therapeutic Development of Novel STING Inhibitors to Treat Parkinson's Disease Neuroinflammation
… We will also conduct IND-enabling toxicology studies in multiple preclinical models. Impact on Diagnosis/Treatment … toxicology studies, we will complete a full assessment of systemic and CNS metrics. We also plan to engage interested …
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Staff on the Move: Foundation’s Unique Role in Venture Philanthropy
October 7, 2013
… Venture Support.’ Karen Chen, PhD, from the Spinal Muscular Atrophy Foundation also will speak on the foundation role; …
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Screen for Novel Glucocerebrosidase-Interacting Parkinson's Genes
… characteristic Parkinson’s disease pathology in the nervous system, as well as for motor problems (such as difficulty … of when GBA leads to degeneration of neurons in the nervous system. We expect that our screen will identify novel genes … Parkinson’s disease. With this study we expect to identify multiple genes with previously unrecognized roles in …
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Global Efforts & Resources in Parkinson’s Research
… Disease The study, a collaborative effort between multiple nonprofit partner organizations and industry … Parkinson's Disease is Moving Towards a Biological Staging System Much like Alzeihmer's and Huntington's, Parkinson‘s disease is moving towards a biologic staging system, with a potentially transformational impact on …