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Developing Wiring Diagrams of the Brain-Body Connection
… the neural networks that control an example of each system. Hypothesis: Understanding the wiring diagrams that … we will study the celiac ganglion, which innervates multiple internal organs, including the esophagus, stomach, …
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Researchers Looking to Improve Diagnosis of Parkinson’s
April 4, 2016
… outside of the brain helped to inform the recently launched Systemic Synuclein Sampling Study (S4). S4 will evaluate alpha-synuclein in multiple locations (saliva, blood and spinal fluid, in …
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Almira (Ellie) Chabi, MD
… International. Dr. Chabi leads programs across multiple therapeutic areas including neurology, immunology, … within Ophthalmology as well as Neuroscience leading to multiple successful NDA filings. In addition to expertise … Program and has served as a board representative in multiple companies. …
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Michael J. Fox Foundation and Sanofi Launch Clinical Trial for Drug to Treat Parkinson’s-Related Cognitive Decline
January 21, 2013
… Parkinson's in different ways.” Researchers believe that multiple systems are at work in cognitive dysfunction in PD, including the dopaminergic system known for its role in the motor symptoms of the …
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Pre-clinical Development of a Parkinson's Disease Therapy Using a Glucagon-Like Peptide (GLP)-1 Receptor Agonist
… neurochemical, and histopathological deficits in multiple rodent models of PD. Exendin-4 has the potential to … A manuscript describing the effects of exendin-4 on multiple therapeutic endpoints, including neurobehavioral … in vivo, it has been shown to have robust efficacy in multiple rodent models of PD, and it is already an …
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Warren D. Hirst, PhD
… α-synuclein antibody, which is in Phase 2 trials, using multiple modalities, from antibodies and antisense … grant review committees, and as an ad-hoc reviewer for multiple journals including Neuron and PNAS. Warren has received multiple grants in addition to serving as a reviewer and …