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Modeling Parkinson’s Disease in Pre-clinical Models and Models Via Overexpression of Irregular-type and Mutant Alpha-synuclein
… disease is a serious brain condition that causes problems with movement and other body functions. Scientists … alpha-synuclein into each model brains will cause movement problems and changes in brain chemicals, similar to what …
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John A. Gruner, PhD
… of action analgesic agents; and actions of drugs on sleep and wake activity. He was a critical discovery team …
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Dealing with Parkinson's Disease Caregiver Stress and Burnout
September 21, 2015
… care can go a long way. Exercise regularly and get enough sleep. Regular exercise has been linked to decreased … effective. Studies suggest that exercise may also help you sleep better at night . Nancy Ryerson …
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Continuous Subcutaneous Administration of Levodopa/Carbidopa (ND0612) for the Treatment of Parkinson's Disease
… and activity of daily living, quality of life, quality of sleep and “on-off” periods during visit days. Oral levodopa … 0.4h and 1.4h with placebo). ND0612L improved quality of sleep by 30% compared to 1% in the placebo group, expressed by reduction in the Parkinson’s Disease Sleep Scale (PDSS). This supports the intended treatment …
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Playing to Win: The Fifth Annual Poker Tournament and Casino Night to Benefit The Michael J. Fox Foundation for Parkinson's Research
February 7, 2012
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Susan H. Fox, MB ChB, MRCP(UK), Ph
… disease mechanisms, particularly neuropsychiatric problems of PD; as well as phase II and phase III clinical …