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Validation of the 18kDa Translocator Protein as a Novel Immunomodulator to Slow Progression in Parkinson's Disease
… Study Rationale: The immune system in the brain has two distinct modes: mode one is … In Parkinson's disease (PD), we think that the immune system goes into the wrong mode; instead of going into mode … Fighting infection causes collateral damage so the immune system fails to protect nerve cells. We think that drugs …
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Parkinson’s Disease: More Than a Movement Disorder?
April 1, 2013
… explained, research indicates that Parkinson’s may involve multiple systems in the body beyond the central nervous system, and it may affect these systems before the motor …
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The Michael J. Fox Foundation’s strategies for accelerating translation of LRRK2 into therapies for Parkinson’s disease
August 10, 2020
… disease (PD)-associated protein LRRK2. MJFF has spearheaded multiple public/private pre-competitive collaborations that …
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Jessika Suescun, MD
… Since 2014, Dr. Suescun has co-developed and executed multiple observational and interventional clinical trials …
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Thomas Briston, PhD/MPharm
… Briston joined Eisai in 2015 and has since worked across multiple Parkinson’s disease drug discovery projects. He now …
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Erik M. Schwiebert, PhD
… discovery projects using bioassays in human cells. DBM has multiple preclinical hit-to-lead/lead compound programs …