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Massachusetts Passes Legislation to Establish a Parkinson’s Disease Research Registry
November 25, 2024
… This move empowers the Massachusetts Department of Public Health (MDPH) to build a population-based database that can track health and demographic information about the 21,000 people … understanding of links between Parkinson’s and environmental risk factors such as chemical exposure and military …
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$24-Million Public-Private Partnership Expands Investigation of Parkinson's Disease
January 30, 2018
… J. Fox Foundation (MJFF), the National Institutes of Health (NIH) and five life sciences companies today … T he Foundation for the National Institutes of Health will manage the project. The first phase of the … "The Michael J. Fox Foundation, the National Institutes of Health, industry partners and thousands of research …
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Delayed Start Assessment of Progranulin in a Progressive Rodent Model of Parkinson’s Disease
… work, both behavioral and neuropathological indices of CNS health were maintained in progranulin pretreated models when … the Parkinsonism inducing agent MPTP. Objectives for Supplemental Investigation: Here we propose to test the more … assess both behavioral and neuropathological indices of CNS health in pre-clinical models in which we will induce a …
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Allogeneic Bone marrow-derived Mesenchymal Stem Cells as a Disease-modifying Therapy for Idiopathic Parkinson’s Disease: Phase 2a Double-Blind, Randomized Controlled Trial
… that interact with the surrounding cells, restoring tissue health and allowing cells to regenerate. With these … of mesenchymal stem cells taken from the bone marrow of a healthy donor will significantly slow the progression of PD … stem cells can stop the disease process and thus restore health to the brain microenvironment. By ending the …
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Defining Mechanisms in Different Brain Cells that Drive Progression in Parkinson’s Disease
… — a non-neuronal type of helper cell that supports the health and activity of neurons — may play a significant role … neurons of oligodendrocytes and explore the health of these cells individually and how they interact …
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Longitudinal Endpoint Optimization to Provide an Assessment of Relevant Drugs in Parkinson’s Disease (LEOPARD-PD)
… Study Rationale: The Parkinson’s Disease-Health Index (PD-HI) is a novel, disease specific … clinical trials to track clinically meaningful changes in health in response to therapeutic intervention in … PD-HI to measure small but clinically relevant changes in health in response to therapeutic intervention. Next Steps …