The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Target Advancement Program, 2016Assessing the PINK1 Pathway in Parkinson
Study Rationale:
Rare mutations in the PINK1 gene cause familial (inherited) Parkinson's disease (PD). However, it is not known if PINK1 contributes to the development of idiopathic (no known cause) PD... -
Research Grant, 2016Investigation of LRRK2 as a Regulator of Dendritic Cell Function
Promising Outcomes of Original Grant:
Myeloid cells (white blood cells) of the immune system include monocytes, neutrophils and dendritic cells found in circulation, as well as microglia (immune system... -
Therapeutic Pipeline Program, 2016KH176 as a Novel Disease-modifying Therapeutic for Parkinson’s Disease
Study Rationale:
Mitochondrial dysfunction has a prominent role in the process of Parkinson’s disease (PD). Mutations in at least seven genes are known to underlie PD, most of them encode proteins that... -
Therapeutic Pipeline Program, 2016Long-term Cell Restorative Treatment for Parkinson’s Disease
Study Rationale:
Cell replacement therapies for Parkinson’s disease (PD) propose to replace the lost dopaminergic neurons in the brain. Transplanted fetal dopamine neurons have... -
Therapeutic Pipeline Program, 2016USP13 Regulation of Parkin Stability
Study Rationale:
Our data show that the enzyme USP13 is dramatically increased (two-fold) in sporadic Parkinson’s brains, and cell culture studies suggest that USP13 de-ubiquitinates... -
Target Advancement Program, 2016Targeting the Transcriptional Regulator of Autophagy LMX1B for Parkinson's Disease Therapeutic Development
Study Rationale:
LMX1B is a transcription factor that plays an essential role in the development of dopaminergic neurons. We have recently described a new role for LMX1B in dopaminergic neurons as a...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.