The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2021Development of Compounds that Destroy Alpha-Synuclein Aggregates for the Treatment of Parkinson’s Disease
Study Rationale:
Multiple lines of evidence indicate that alpha-synuclein forms aggregates similar to those adopted by infectious prion proteins, and that these toxic clusters are responsible for the... -
Biomarkers, 2021Use of Neuronal Exosomes to Predict Parkinson’s Disease
Study Rationale:
In Parkinson’s disease (PD), the build-up of alpha-synuclein inside nerve cells leads to formation of abnormal clumps and death of dopamine-producing cells and other neurons. By the... -
Environmental Risk Factors, 2021Exposure to Ambient Air Pollution and Risk of Parkinson’s Disease
Study Rationale:
Ambient (outdoor) air pollution can increase the risk of cardiovascular diseases and death. Some evidence links ambient air pollution to higher risk of Parkinson’s disease. But... -
Environmental Risk Factors, 2021Nationwide Geographic Cluster Analysis of Incident Parkinson’s Disease
Study Rationale:
The causes of Parkinson’s disease (PD) are mostly unknown, but non-genetic factors, such as environmental exposures during one’s lifetime, probably affect whether a person develops PD... -
Aligning Science Across Parkinson's, 2020Impaired Integration of Organelle Function in Parkinson’s Disease
Study Rationale:
Geneticists have made great progress in identifying gene mutations that either cause Parkinson’s or increase disease risk. The critical next step is to determine how some of these... -
Aligning Science Across Parkinson's, 2020Dissecting the Mechanisms Underlying Disease Progression
Study Rationale:
The progression of Parkinson’s disease is very variable, with some individuals having a rapid course and others having a longer and more benign course. We believe that by...
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Our funding programs support basic, translational and clinical research from academia and industry.