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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2022
    Self-reported perceptions and self-reported outcomes on motor and non-motor symptoms in the Parkinson's disease continuum: a systematic review of mixed methods

    Study Rationale: People are unique in the way they experience quality of life. Throughout the progression of Parkinson's disease, patients and their care partners have different perceptions of motor...

  • Spring 2022 RFP: Proof-of-Concept Testing of PD Therapeutics, 2022
    Identification and quantification of Parkinson’s Disease progression using digital measures from a wrist-worn wearable device - a retrospective study

    Study Rationale: The combination of digital measures and machine learning (ML) holds great promise for improving critical aspects of Parkinson’s disease (PD) care, practice and research. Earlier PD...

  • Spring 2022 RFP: Proof-of-Concept Testing of PD Therapeutics, 2022
    Project Title: Clinical Development of PDM608, a Potential Neuroprotective and Anti-inflammatory Long-acting Biologic for Parkinson’s Disease

    Study Rationale: Targeting neuroinflammation by increasing T regulatory cell numbers is a promising strategy for treating Parkinson’s disease. We propose a Phase 1 trial in non-PD volunteers for our...

  • Spring 2022 RFA: Target Advancement Program - Target Validation, 2022
    Validating BMPs as novel drug candidates for Parkinson’s disease

    Study Rationale: Neurotrophic factors are prime candidates for the development of disease-modifying therapies, based on their properties to restore and maintain the functional integrity of neurons...

  • Spring 2022 RFA: Target Advancement Program - Tool Generation, 2022
    Design and testing of a FRET sensor for Parkin activity

    Study Rationale: Parkin is a protein that is encoded by a gene which is frequently mutated in Parkinson’s disease. It is known to be involved in getting rid of damaged mitochondria in cells and this...

  • Spring 2022 RFA: Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Evaluating a Microbial Biomarker in Blood Samples for Parkinson’s Disease

    Study Rationale: Diagnosing Parkinson’s disease (PD) currently involves evaluation by movement disorder specialists and assessment based on physical examination and questionnaires. This approach is...

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