The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2003Adenosine A2A Receptors in a Pre-clinical Model of PD Dyskinesias
Gradual slowing of movement in Parkinson's disease (PD) is due to the steady decline in brain levels of dopamine, a chemical signal that facilitates normal movement. Our most effective medications for...
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Community Fast Track, 2003Morphology Specific Antibodies as Potential Therapeutics
Parkinson's Disease has been correlated with the over expression and misfolding of the protein a-synuclein. This protein is abundantly produced in nerve cells in the brain and is the major component...
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Community Fast Track, 2003Anti-inflammatory Effects of Nicotine in Parkinson’s Disease
Parkinson's disease (PD) is a progressive, debilitating movement disorder resulting from the death of the dopamine-synthesizing neurons and, consequently, dopamine deficiency in the basal ganglia, i.e...
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Community Fast Track, 2003Development of the Midbrain Dopaminergic Pathways
Parkinson's disease is a result of degeneration of the midbrain dopaminergic (DA) neurons. In the treatment of Parkinson's disease, replacing lost neurons is a promising therapy. However, the progress...
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Community Fast Track, 2003In vivo investigation of DJ-1 function in DJ-1 knockout mice
Two genetic mutations in the DJ-1 gene have been identified earlier this year that can cause early-onset Parkinson's disease. Since both mutations are believed to cause loss of function of the DJ-1...
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The Role of Inflammation in Parkinson's Disease, 2003The Role of TNF-Mediated Dopaminergic Neurotoxicity in Parkinson's Disease: Novel Anti-TNF Biologics as Biochemical Tools and New Therapeutic Agents
Loss of dopamine-producing neurons is a hallmark of Parkinson's disease and inflammation-driven oxidative stress is believed to play a significant role in this neurodegenerative process.
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Our funding programs support basic, translational and clinical research from academia and industry.