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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Access to Data and Biospecimens, 2014
    Defining Non-motor Phenotypes in Parkinson’s Disease and Novel Strategies for Diagnosis

    Objective/Rationale:
    Although Parkinson’s disease (PD) is diagnosed as a movement disorder, motor deficits are preceded by non-motor features including cognitive, cardiovascular, gastrointestinal...

  • Alpha-synuclein Pathology, 2014
    Contrasting Pathological Versus Normal Alpha-synuclein Assemblies

    Study Rationale:                   
    Parkinson’s disease (PD) is characterized by Lewy bodies composed of the protein alpha-synuclein in dopamine-producing nerve cells. The protein aggregates are also...

  • Research Grant, 2014
    Validation of the Movement Disorders Society’s Clinical Criteria of Parkinson’s Disease

    Study Rationale:
    Diagnosis of Parkinson’s disease (PD) and other causes of parkinsonism is not always an easy task for physicians. An accurate diagnosis, however, is an essential aspect of care for...

  • Research Grant, 2013
    Longitudinal Characterization of G2019S Models: Physiological and Behavioral Analyses of Dopamine and Glutamate Systems

    Objective/Rationale:
    It is likely in disease states that brain cells suffer long periods of dysfunction before they die. By studying the early effects of Parkinson’s disease (PD) gene mutations upon...

  • LRRK2 Cohort Consortium Resource Request, 2013
    Alpha-synuclein and Other Biomarkers in Biological Samples of LRRK2 Parkinson’s Disease

    Objective/Rationale:
    Cerebrospinal fluid (CSF) biomarkers of Alzheimer’s pathology have been investigated in Parkinson’s disease (PD), and abnormal CSF protein levels (tau and phosphorylated tau, beta...

  • Clinical Intervention Awards, 2007
    Serotonin and Sleep Disordered Breathing in Parkinson Disease

    Objective/Rationale:
    Sleep related problems are a major cause of impairment in Parkinson's disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing...

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