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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2013
    Structure-based Design of Pharmacological Activators of Parkin

    Objective/Rationale:             
    Mutations in the Parkin gene are responsible for a familial form of Parkinson’s disease (PD). The gene encodes a protein whose activity has been shown to protect...

  • Research Grant, 2013
    LRRK2 Role on Auto-antibody Production by Human B Cells

    Objective/Rationale:             
    B lymphocytes are cells of the immune system that have a dual function: they produce antibodies to fight disease-causing agents, and they participate in the...

  • RRIA (Rapid Response Innovation Awards), 2013
    Role of GSK-3beta in Parkinson’s Disease

    The protein GSK-3beta has not previously been linked to Parkinson’s disease (PD). Recently, we have studied pre-clinical models with high levels of GSK-3beta throughout the brain. At a younger age [up...

  • MJFF Research Grant, 2013
    Validation and Characterization of Exosomal Alpha-synuclein as a Diagnostic Marker for Parkinson’s Disease

    Parkinson’s disease (PD) is characterized by aggregation of the intracellular alpha-synuclein protein and subsequent neurodegeneration. Recent findings suggest that extracellular alpha-synuclein forms...

  • Research Grant, 2013
    Ubiquitous, Inexpensive Non-invasive Technologies for Objective Detection and Monitoring of Parkinson’s Symptoms

    Objective/Rationale:
    For doctors to diagnose and treat Parkinson’s, they need reliable tests. Unfortunately, testing the symptoms of Parkinson’s at a specialist’s office/clinic is expensive and time...

  • Research Grant, 2013
    Prion-like Dissemination of Synuclein Pathology: A Non-human Study

    Objective/Rationale:
    Parkinson’s disease (PD) is characterized by the loss of midbrain dopaminergic neurons and the presence of aggregates named Lewy bodies. This pathology is believed to drive the...

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