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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2021
    Understand Me for Life: An Intelligibility App for Parkinson's Disease

    Study Rationale:
    Approximately 90% of people with Parkinson’s develop speech and language problems over the course of the disease, and more than half of these speakers experience problems with...

  • Research Grant, 2021
    Hypoxia (Lowering Oxygen Levels) as a Novel Treatment for Parkinson’s Disease

    Study Rationale:
    Many anecdotes suggest that people with Parkinson’s disease (PD) can experience a marked improvement in symptoms when they travel to the mountains or during flights at high altitude...

  • Target Advancement Program, 2021
    Modulation of Epigenetic Regulator HDAC4 as a Parkinson’s Treatment

    Study Rationale:
    Scientists can take skin cells from people with Parkinson’s disease (PD), turn them into stem cells, and then engineer them into dopamine neurons, the cell type lost in PD. Our...

  • Therapeutic Pipeline Program, 2021
    Dietary Interventions to Slow and Improve Parkinson’s Symptoms by Restructuring the Gut Microbiome and Decreasing Inflammation

    Study Rationale:
    There is a link between the gut and the brain in Parkinson’s disease (PD), and gut bacteria may play an important role. Gut bacteria they affect the bowel mucus barrier, produce...

  • Priority Biology, 2021
    LRRK2 Regulation of Melanoma Progression

    Study Rationale:
    People with Parkinson's disease (PD) are more likely to develop melanoma, and people with melanoma are more likely to develop PD than the general population. Additionally, melanoma...

  • Therapeutic Pipeline Program, 2021
    RNA Targeting Small Molecules as Therapeutics for Parkinson's

    Study Rationale:    
    Abnormal clumping of the protein alpha-synuclein is a hallmark of Parkinson's disease (PD) and a likely cause of neurodegeneration and, ultimately, symptoms. One of the causes...

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